2024
Global and Regional Cardiovascular Mortality Attributable to Nonoptimal Temperatures Over Time
Hundessa S, Huang W, Zhao Q, Wu Y, Wen B, Alahmad B, Armstrong B, Gasparrini A, Sera F, Tong S, Madureira J, Kyselý J, Schwartz J, Vicedo-Cabrera A, Hales S, Johnson A, Li S, Guo Y, Jaakkola J, Ryti N, Urban A, Tobias A, Royé D, Lavigne E, Ragettli M, Åström C, Raz R, Pascal M, Kan H, Goodman P, Zeka A, Hashizume M, Diaz M, Seposo X, Nunes B, Kim H, Lee W, Íñiguez C, Guo Y, Pan S, Zanobetti A, Dang T, Van Dung, Schneider A, Entezari A, Analitis A, Forsberg B, Ameling C, Houthuijs D, Indermitte E, Mayvaneh F, Acquaotta F, de'Donato F, Carrasco-Escobar G, Orru H, Katsouyanni K, de Sousa Zanotti Stagliorio Coelho M, Ortega N, Scovronick N, Michelozzi P, Correa P, Saldiva P, Abrutzky R, Osorio S, Colistro V, Huber V, Honda Y, Kim Y, Bell M, Xu R, Yang Z, Roradeh H, Arellano E, Rao S, Chua P, da Silva S, da Silva S, De la Cruz Valencia C. Global and Regional Cardiovascular Mortality Attributable to Nonoptimal Temperatures Over Time. Journal Of The American College Of Cardiology 2024, 83: 2276-2287. PMID: 38839202, DOI: 10.1016/j.jacc.2024.03.425.Peer-Reviewed Original ResearchConceptsCardiovascular deathCardiovascular mortalityExcess mortality ratesCardiovascular mortality riskMultivariate meta-regression modelTemperature-mortality associationsMeta-regression modelsTemperature-related deathsMortality burdenMortality riskEffect estimatesHeat-related deathsSub-Saharan AfricaMortality attributesTemporal trendsCold-related deathsMortality rateGlobal assessmentSub-SaharanInvestigated spatiotemporal trendsDeath ratioMortalityBurdenComprehensive global assessmentDeath
2023
Air Pollution and Acute Kidney Injury in the U.S. Medicare Population: A Longitudinal Cohort Study
Lee W, Wu X, Heo S, Kim J, Fong K, Son J, Sabath M, Trisovic A, Braun D, Park J, Kim Y, Lee J, Schwartz J, Kim H, Dominici F, Al-Aly Z, Bell M. Air Pollution and Acute Kidney Injury in the U.S. Medicare Population: A Longitudinal Cohort Study. Environmental Health Perspectives 2023, 131: 047008. PMID: 37036790, PMCID: PMC10084931, DOI: 10.1289/ehp10729.Peer-Reviewed Original ResearchConceptsAcute kidney injuryFirst hospital admissionLongitudinal cohort studyHospital admissionKidney injuryCohort studyHazard ratioPopulation-based longitudinal cohort studyU.S. Medicare populationYears of ageAir pollution exposureNationwide Medicare dataPublic health policyCurrent National Ambient Air Quality StandardHealth care expendituresKidney functionDisease burdenMedicare populationMedicare dataLong-term exposureAdmissionPollution exposureHealth policyCare expendituresEffect estimatesEffects of heat waves on cardiovascular and respiratory mortality in Rio de Janeiro, Brazil
Silveira I, Cortes T, Bell M, Junger W. Effects of heat waves on cardiovascular and respiratory mortality in Rio de Janeiro, Brazil. PLOS ONE 2023, 18: e0283899. PMID: 37000782, PMCID: PMC10065291, DOI: 10.1371/journal.pone.0283899.Peer-Reviewed Original ResearchConceptsRespiratory mortalityOdds ratioDistributed lag non-linear modelCardiovascular mortalityIndividual-level exposuresHeat wave intensityCase-crossover studyConditional logistic regressionMunicipal Health DepartmentHeat wavesEffects of heat wavesHealth impacts of heat wavesHealth departmentsHealth resourcesDeath dataOlder peopleLow-incomeEffect estimatesOlder womenDefinition of heat wavesLogistic regressionEpidemiological evidenceMorbidity outcomesHeat wave daysHealth impacts
2017
Effects of ambient PM1 air pollution on daily emergency hospital visits in China: an epidemiological study
Chen G, Li S, Zhang Y, Zhang W, Li D, Wei X, He Y, Bell ML, Williams G, Marks GB, Jalaludin B, Abramson MJ, Guo Y. Effects of ambient PM1 air pollution on daily emergency hospital visits in China: an epidemiological study. The Lancet Planetary Health 2017, 1: e221-e229. PMID: 29851607, DOI: 10.1016/s2542-5196(17)30100-6.Peer-Reviewed Original ResearchConceptsEmergency hospital visitsDaily emergency hospital visitsHospital visitsEpidemiological studiesHealth effectsAmbient PMMean daily numberTime series Poisson regressionAmbient air pollutionCause-effect associationPoisson regressionVisitsLarge hospitalsEffect estimatesHigher RRStatistical significanceLag 0Daily numberHospitalMean daily concentrationsDaily countsAir pollutionDaily PMDaily concentrationsSevere ambient air pollution
2015
Air pollution and mortality in São Paulo, Brazil: Effects of multiple pollutants and analysis of susceptible populations
Bravo MA, Son J, de Freitas CU, Gouveia N, Bell ML. Air pollution and mortality in São Paulo, Brazil: Effects of multiple pollutants and analysis of susceptible populations. Journal Of Exposure Science & Environmental Epidemiology 2015, 26: 150-161. PMID: 25586330, DOI: 10.1038/jes.2014.90.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAir PollutantsAir PollutionBrazilCarbon MonoxideCardiovascular DiseasesCase-Control StudiesDeath CertificatesEnvironmental MonitoringFemaleHumansLogistic ModelsMaleMiddle AgedNitrogen DioxideOzoneParticle SizeParticulate MatterRespiratory Tract DiseasesRisk FactorsSex DistributionSocioeconomic FactorsSulfur DioxideConceptsTime of deathSocioeconomic statusTime-stratified case-crossover analysisCase-crossover analysisResidential socioeconomic statusEducation groupHospital deathCardiovascular mortalityNon-accidental mortalityRespiratory mortalityMortality riskHigh education groupEvidence of differencesSignificant associationMortalityEffect estimatesDeathMortality effectsSusceptible populationHealth impactsAmbient monitorsIndividual-level health dataAir pollutionHealth dataAerodynamic diameter
2012
Relationship between birth weight and exposure to airborne fine particulate potassium and titanium during gestation
Bell ML, Belanger K, Ebisu K, Gent JF, Leaderer BP. Relationship between birth weight and exposure to airborne fine particulate potassium and titanium during gestation. Environmental Research 2012, 117: 83-89. PMID: 22705336, PMCID: PMC3418490, DOI: 10.1016/j.envres.2012.05.004.Peer-Reviewed Original ResearchConceptsLow birth weightBirth weightAdverse pregnancy outcomesPregnancy outcomesTerm infantsAirborne fine particulate matterStudy populationIQR increaseMothers' exposureAfrican American mothersFirst birthInfantsEffect estimatesConfidence intervalsWhite mothersPregnancyHealth impactsRiskExposureFine particulate matterMothersMost studiesGestationWeightAssessment of the health impacts of particulate matter characteristics.
Bell ML. Assessment of the health impacts of particulate matter characteristics. Research Report 2012, 5-38. PMID: 22393584.Peer-Reviewed Original ResearchConceptsHealth effect estimatesCardiovascular hospital admissionsHospital admissionEffect estimatesMortality effect estimatesHealth effectsCause of hospitalizationAir pollution-related health effectsInterquartile range increasePollution-related health effectsRespiratory hospital admissionsAdverse health effectsHealth effects dataCardiovascular hospitalizationRespiratory hospitalizationsCardiovascular admissionsHigh prevalenceHospitalizationAerodynamic diameterAdmissionCommunity-level variablesObserved associationsSocioeconomic statusHealth impactsPM toxicity
2009
Adverse Health Effects of Particulate Air Pollution
Bell ML, Ebisu K, Peng RD, Dominici F. Adverse Health Effects of Particulate Air Pollution. Epidemiology 2009, 20: 682-686. PMID: 19535984, PMCID: PMC3164531, DOI: 10.1097/ede.0b013e3181aba749.Peer-Reviewed Original ResearchConceptsCardiovascular hospitalizationAC prevalenceEffect estimatesAdverse health effectsParticulate air pollutionHealth effect estimatesRespiratory hospitalizationsMorbidity differsHospitalizationShort-term effectsPrevalenceHealth effectsDay associationsMortalityPM effectsAssociationParticulate matter
2008
Seasonal and Regional Short-term Effects of Fine Particles on Hospital Admissions in 202 US Counties, 1999–2005
Bell ML, Ebisu K, Peng RD, Walker J, Samet JM, Zeger SL, Dominici F. Seasonal and Regional Short-term Effects of Fine Particles on Hospital Admissions in 202 US Counties, 1999–2005. American Journal Of Epidemiology 2008, 168: 1301-1310. PMID: 18854492, PMCID: PMC2732959, DOI: 10.1093/aje/kwn252.Peer-Reviewed Original ResearchMeSH KeywordsAgedAir PollutantsAir PollutionAlgorithmsCardiovascular DiseasesData Interpretation, StatisticalDatabases, FactualEnvironmental MonitoringEpidemiological MonitoringHospitalizationHumansMedicareParticle SizeParticulate MatterPatient AdmissionRespiratory Tract DiseasesRetrospective StudiesSeasonsTime FactorsUnited StatesEffect Modification by Community Characteristics on the Short-term Effects of Ozone Exposure and Mortality in 98 US Communities
Bell ML, Dominici F. Effect Modification by Community Characteristics on the Short-term Effects of Ozone Exposure and Mortality in 98 US Communities. American Journal Of Epidemiology 2008, 167: 986-997. PMID: 18303005, PMCID: PMC2430754, DOI: 10.1093/aje/kwm396.Peer-Reviewed Original ResearchConceptsBlack/African American populationsHigher effect estimatesHigh health burdenEffect modificationHealth burdenUS urban communitiesMortality riskAfrican American populationShort-term exposureHealth statusShort-term effectsCommunity-level characteristicsNational MorbidityMortalityUS communitiesEffect estimatesExposureOzone exposureCommunity-specific characteristicsUS CensusRiskMorbidityUrban communitiesPopulationPrevalence
2007
Potential Confounding of Particulate Matter on the Short-Term Association between Ozone and Mortality in Multisite Time-Series Studies
Bell ML, Kim JY, Dominici F. Potential Confounding of Particulate Matter on the Short-Term Association between Ozone and Mortality in Multisite Time-Series Studies. Environmental Health Perspectives 2007, 115: 1591-1595. PMID: 18007990, PMCID: PMC2072830, DOI: 10.1289/ehp.10108.Peer-Reviewed Original ResearchConceptsPotential confoundingShort-term effectsMultisite time-series studyShort-term associationsMortality associationLikely confoundersU.S. urban communitiesShort-term exposureStudy daysTime-series studyMortalityStudy periodEffect estimatesConfoundersFurther investigationAssociationAmbient exposureMortality relationshipConfoundingDaysAerodynamic diameterExposureCovariatesDaily PM concentrationsUrban communitiesAmbient Air Pollution and Low Birth Weight in Connecticut and Massachusetts
Bell ML, Ebisu K, Belanger K. Ambient Air Pollution and Low Birth Weight in Connecticut and Massachusetts. Environmental Health Perspectives 2007, 115: 1118-1124. PMID: 17637932, PMCID: PMC1913584, DOI: 10.1289/ehp.9759.Peer-Reviewed Original ResearchConceptsLow birth weightBirth weightThird trimesterType of deliveryAmbient air pollutionGestational exposureMaternal exposureFirst trimesterGestational lengthPrenatal careMother's residenceInterquartile increaseTobacco useTrimesterEffect estimatesMarital statusMother's raceWhite mothersChild sexBirth orderBlack mothersContinuous variablesAir pollutionExposureMothers
2005
A Meta-Analysis of Time-Series Studies of Ozone and Mortality With Comparison to the National Morbidity, Mortality, and Air Pollution Study
Bell ML, Dominici F, Samet JM. A Meta-Analysis of Time-Series Studies of Ozone and Mortality With Comparison to the National Morbidity, Mortality, and Air Pollution Study. Epidemiology 2005, 16: 436-445. PMID: 15951661, PMCID: PMC3581312, DOI: 10.1097/01.ede.0000165817.40152.85.Peer-Reviewed Original ResearchConceptsTime-series studyShort-term associationsPublication biasNational MorbidityCause-specific mortalityLag 0Meta-analysis resultsPossible publication biasCity-specific estimatesPooled effectRespiratory mortalityMeta-AnalysisTotal mortalityAge groupsMortalityEffect estimatesMorbidityPositive associationNMMAPSInconclusive resultsAir pollution studiesAssociationOzone exposureEvidenceStrong evidence
2004
Ozone and Short-term Mortality in 95 US Urban Communities, 1987-2000
Bell ML, McDermott A, Zeger SL, Samet JM, Dominici F. Ozone and Short-term Mortality in 95 US Urban Communities, 1987-2000. JAMA 2004, 292: 2372-2378. PMID: 15547165, PMCID: PMC3546819, DOI: 10.1001/jama.292.19.2372.Peer-Reviewed Original ResearchConceptsUS urban communitiesRespiratory mortalityShort-term exposureNumerous time series studiesShort-term mortalitySingle-day exposureLarge US communitiesAdverse health effectsTotal US populationHospital admissionRespiratory illnessTime-varying confoundersMAIN OUTCOMEUS populationSignificant associationTime-series studyMortalityNational MorbidityUS communitiesEffect estimatesHealth effectsPrevious weekUrban communitiesDaily mortalityPublic health