2016
Mitochondria controlled by UCP2 determine hypoxia-induced synaptic remodeling in the cortex and hippocampus
Varela L, Schwartz ML, Horvath TL. Mitochondria controlled by UCP2 determine hypoxia-induced synaptic remodeling in the cortex and hippocampus. Neurobiology Of Disease 2016, 90: 68-74. PMID: 26777666, DOI: 10.1016/j.nbd.2016.01.004.Peer-Reviewed Original ResearchConceptsHippocampal neuronsMitochondria-endoplasmic reticulum interactionUCP2-KO miceEarly postnatal exposureLoss of synapsesOxygen tensionHigher brain regionsAdaptive mitochondrial responsesProtein 2 expressionHypothalamic circuitsPostnatal exposureKO miceSynaptic remodelingSystemic metabolismSynaptic inputsBrain cellsMetabolic controlNeuronal mitochondriaBrain regionsAdaptive responseNeuronsHippocampusMitochondrial dynamicsMetabolic challengesCortex
2007
Astroglial Cells in Development, Regeneration, and Repair
Vaccarino FM, Fagel DM, Ganat Y, Maragnoli ME, Ment LR, Ohkubo Y, Schwartz ML, Silbereis J, Smith KM. Astroglial Cells in Development, Regeneration, and Repair. The Neuroscientist 2007, 13: 173-185. PMID: 17404377, DOI: 10.1177/1073858406298336.Peer-Reviewed Original Research In PressConceptsFibroblast growth factor receptorAstroglial cellsGenetic fate mappingCell divisionLineage studiesGrowth factor receptorPostnatal CNSEmbryonic CNSMain cellular componentsFate mappingNeuronal differentiationCellular componentsCell typesInjury-induced increaseFactor receptorNeurogenic nichePerinatal injuryCerebral cortexYoung miceCellsOligodendrocytesNeuronsDifferent rolesCNSNiche
1990
Development and Plasticity of the Primate Cerebral Cortex
Schwartz M, Goldman-Rakic P. Development and Plasticity of the Primate Cerebral Cortex. Clinics In Perinatology 1990, 17: 83-102. PMID: 2318019, DOI: 10.1016/s0095-5108(18)30591-8.Peer-Reviewed Original ResearchConceptsPrefrontal cortexSensory areasCorticocortical connectivitySensory regionsPrimate cerebral cortexSensory cortical regionsMonkey prefrontal cortexCallosal neuronsCerebral cortexSynaptic contactsPostnatal periodAssociation areasVisual cortexCortical regionsPrenatal periodCortexNonsensory regionsAdultlike patternNonhuman primatesConnectional organizationDendritic surfaceMonthsEarly appearanceEnvironmental stimulationStimulation