2009
Hypoxic Injury during Neonatal Development in Murine Brain: Correlation between In Vivo DTI Findings and Behavioral Assessment
Chahboune H, Ment LR, Stewart WB, Rothman DL, Vaccarino FM, Hyder F, Schwartz ML. Hypoxic Injury during Neonatal Development in Murine Brain: Correlation between In Vivo DTI Findings and Behavioral Assessment. Cerebral Cortex 2009, 19: 2891-2901. PMID: 19380380, PMCID: PMC2774398, DOI: 10.1093/cercor/bhp068.Peer-Reviewed Original ResearchConceptsChronic sublethal hypoxiaLow birth weight preterm infantsBirth weight preterm infantsHypoxia-induced modificationNeonatal rodent modelPreterm birth resultsWeight preterm infantsSignificant neurodevelopmental disabilitiesOpen field taskGreater locomotor activityPreterm infantsPreterm birthNeurodevelopmental consequencesBirth resultsHypoxic injurySomatosensory cortexCaudate putamenCallosal connectivityCorpus callosumBehavioral deficitsNeurodevelopmental disabilitiesRodent modelsNeonatal developmentDTI findingsSublethal hypoxia
1998
Association of chronic sublethal hypoxia with ventriculomegaly in the developing rat brain
Ment L, Schwartz M, Makuch R, Stewart W. Association of chronic sublethal hypoxia with ventriculomegaly in the developing rat brain. Brain Research 1998, 111: 197-203. PMID: 9838111, DOI: 10.1016/s0165-3806(98)00139-4.Peer-Reviewed Original ResearchConceptsChronic sublethal hypoxiaSublethal hypoxiaBronchopulmonary dysplasiaAnimal modelsExperimental rat pupsSystemic blood pressureSubcortical white matterCorpus callosum sizePostnatal day 3Third groupNeurodevelopmental handicapPreterm infantsProlonged hypoxemiaBlood pressureCerebral ventriculomegalyExperimental time pointsChronic hypoxiaControl ratsCortical volumeRat pupsCallosum sizeNewborn ratsRat brainBody weightDay 3