1998
Novel paracrine signaling mechanism in the ocular ciliary epithelium
Hirata K, Nathanson M, Sears M. Novel paracrine signaling mechanism in the ocular ciliary epithelium. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 8381-8386. PMID: 9653195, PMCID: PMC20984, DOI: 10.1073/pnas.95.14.8381.Peer-Reviewed Original ResearchConceptsNonpigmented cell layerCiliary epithelial bilayerAlpha1-adrenergic antagonist prazosinBeta-adrenergic antagonist propranololPigmented cell layerGap junction blocker octanolBeta-adrenergic agonist isoproterenolCell layerEpithelial bilayerEndogenous adenylyl cyclaseGap junctionsCell spreadOcular ciliary epitheliumAntagonist prazosinAqueous humor secretionAntagonist propranololCiliary bodyAgonist isoproterenolParacrine pathwaysAdrenergic stimulationNovel paracrineCytosolic Ca2Lucifer YellowCiliary epitheliumAdenylyl cyclase
1997
Intercellular Calcium Signaling in Liver
Nathanson M, Fallon M, Burgstahler A, Mennone A, Schlosser S, Gonzalez C, Sáez J. Intercellular Calcium Signaling in Liver. Series Of The Centro De Estudios Científicos 1997, 469-481. DOI: 10.1007/978-1-4899-1795-9_27.Peer-Reviewed Original ResearchGap junctionsGap junction expressionIntercellular calcium signalingDiverse cell functionsExcitable cell typesBile secretionIsolated cell systemImportant second messengerJunction expressionCytosolic Ca2Experimental modelHormonal stimulationCell functionPhysiological circumstancesCalcium signalingIntercellular signalingHepatocytesSecond messengerOrgan-level responsesPreliminary evidenceLiverCell typesCai2Inositol 1Signaling