2024
Translational Research of the Acute Effects of Negative Emotions on Vascular Endothelial Health: Findings From a Randomized Controlled Study
Shimbo D, Cohen M, McGoldrick M, Ensari I, Diaz K, Fu J, Duran A, Zhao S, Suls J, Burg M, Chaplin W. Translational Research of the Acute Effects of Negative Emotions on Vascular Endothelial Health: Findings From a Randomized Controlled Study. Journal Of The American Heart Association 2024, 13: e032698. PMID: 38690710, PMCID: PMC11179860, DOI: 10.1161/jaha.123.032698.Peer-Reviewed Original ResearchConceptsEndothelial cell-derived microparticlesEndothelium-dependent vasodilationCell-derived microparticlesEndothelial progenitor cellsGroup x time interactionEndothelial cell healthCirculating bone marrow-derived endothelial progenitor cellsIncreased risk of cardiovascular disease eventsIndex scoreEndothelial healthProgenitor cellsImpaired endothelium-dependent vasodilationRisk of cardiovascular disease eventsAcute effectsTime interactionBone marrow-derived endothelial progenitor cellsMarrow-derived endothelial progenitor cellsRecall taskStatistically significant group x time interactionsSignificant group x time interactionRandomized controlled studyCardiovascular disease eventsVascular endothelial healthRandomized controlled experimental studyNegative emotions
2015
Ambulatory Medical Follow-Up in the Year After Surgery and Subsequent Survival in a National Cohort of Veterans Health Administration Surgical Patients
Schonberger RB, Dai F, Brandt C, Burg MM. Ambulatory Medical Follow-Up in the Year After Surgery and Subsequent Survival in a National Cohort of Veterans Health Administration Surgical Patients. Journal Of Cardiothoracic And Vascular Anesthesia 2015, 30: 671-679. PMID: 27021176, PMCID: PMC5499041, DOI: 10.1053/j.jvca.2015.12.019.Peer-Reviewed Original ResearchConceptsFirst postoperative yearPostoperative yearNational cohortPostsurgical yearSurgical patientsLong-term postoperative survivalVeterans Health Administration facilitiesFirst postsurgical yearRetrospective cohort studyPostoperative year 1Day of surgeryAmbulatory medical careHazard of deathPostoperative year 2Medical Follow-UpYear 2US veterans' hospitalsYear 1Cause mortalityPostoperative survivalCohort studyPatient subgroupsCare coordinationFollow-upUS veterans
2014
Confluence of Depression and Acute Psychological Stress Among Patients With Stable Coronary Heart Disease: Effects on Myocardial Perfusion
Burg MM, Meadows J, Shimbo D, Davidson KW, Schwartz JE, Soufer R. Confluence of Depression and Acute Psychological Stress Among Patients With Stable Coronary Heart Disease: Effects on Myocardial Perfusion. Journal Of The American Heart Association 2014, 3: e000898. PMID: 25359402, PMCID: PMC4338683, DOI: 10.1161/jaha.114.000898.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedChi-Square DistributionChronic DiseaseConnecticutCoronary CirculationCoronary DiseaseDepressionFemaleHemodynamicsHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisMyocardial Perfusion ImagingOdds RatioPredictive Value of TestsPsychiatric Status Rating ScalesRecurrenceRisk FactorsSeverity of Illness IndexStress, PsychologicalTomography, Emission-Computed, Single-PhotonConceptsAcute psychological stressMyocardial perfusionPsychological stressDepressed rangeNormal rangeAcute coronary syndrome (ACS) recurrenceSelective serotonin reuptake inhibitor medicationsStable coronary heart diseaseCoronary heart disease patientsSerotonin reuptake inhibitor medicationsImpaired myocardial perfusionTomography myocardial perfusionCoronary heart diseaseMortality risk factorsOptimal medical careHigh normal rangeReuptake inhibitor medicationsHeart disease patientsBeck Depression InventorySingle photon emissionACS recurrenceCHD prognosisInhibitor medicationVascular mechanismsMeasures of depression
2013
The association of cardiac vagal control and executive functioning – Findings from the MIDUS study
Kimhy D, Crowley O, McKinley P, Burg M, Lachman M, Tun P, Ryff C, Seeman T, Sloan R. The association of cardiac vagal control and executive functioning – Findings from the MIDUS study. Journal Of Psychiatric Research 2013, 47: 628-635. PMID: 23434176, PMCID: PMC3594003, DOI: 10.1016/j.jpsychires.2013.01.018.Peer-Reviewed Original Research
2012
Endothelial cell activation, reduced endothelial cell reparative capacity, and impaired endothelial-dependent vasodilation after anger provocation
Shimbo D, Rosenberg LB, Chaplin W, Zhao S, Goldensohn ER, Cholankeril M, Fu J, Hong SB, Jelic S, Burg MM. Endothelial cell activation, reduced endothelial cell reparative capacity, and impaired endothelial-dependent vasodilation after anger provocation. International Journal Of Cardiology 2012, 167: 1064-1065. PMID: 23157814, PMCID: PMC3582854, DOI: 10.1016/j.ijcard.2012.10.069.Peer-Reviewed Original Research
2011
Depressive symptom dimensions and cardiac prognosis following myocardial infarction: results from the ENRICHD clinical trial
Bekke-Hansen S, Trockel M, Burg M, Taylor C. Depressive symptom dimensions and cardiac prognosis following myocardial infarction: results from the ENRICHD clinical trial. Psychological Medicine 2011, 42: 51-60. PMID: 21682949, DOI: 10.1017/s0033291711001000.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesCognitive Behavioral TherapyComorbidityDepressive DisorderFemaleHumansMaleMiddle AgedMyocardial InfarctionPrincipal Component AnalysisPrognosisProportional Hazards ModelsPsychiatric Status Rating ScalesRecurrenceRisk FactorsSeverity of Illness IndexSocial IsolationSocial SupportTime FactorsConceptsDepressive symptom dimensionsMyocardial infarctionSomatic depressive symptomsDepressive symptomsCardiovascular mortalityCardiac prognosisClinical trialsSubsequent mortalitySymptom dimensionsCoronary Heart Disease (ENRICHD) clinical trialRecurrent non-fatal myocardial infarctionBeck Depression Inventory itemsNon-fatal myocardial infarctionBonferroni correctionEarly cardiac morbidityAcute myocardial infarctionSomatic symptom severityCardiac morbidityCardiovascular morbidityCause mortalityInitial infarctionCox regressionEnhancing RecoveryPsychosocial interventionsSignificant associationAutonomic Contribution to Endothelin-1 Increase during Laboratory Anger-Recall Stress in Patients with Coronary Artery Disease
Burg MM, Soufer A, Lampert R, Collins D, Soufer R. Autonomic Contribution to Endothelin-1 Increase during Laboratory Anger-Recall Stress in Patients with Coronary Artery Disease. Molecular Medicine 2011, 17: 495-501. PMID: 21267513, PMCID: PMC3105151, DOI: 10.2119/molmed.2010.00083.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseEndothelin-1Parasympathetic activityArtery diseaseAutonomic contributionsChronic stable coronary artery diseaseStable coronary artery diseaseCholinergic antiinflammatory pathwayLaboratory stressCoronary plaque ruptureEndothelin-1 increaseSignificant odds ratioEndothelial cell functionCardiac eventsEndothelial dysfunctionIndwelling catheterAutonomic factorsSympathetic activityAntiinflammatory pathwayAutonomic influencesAutonomic toneOdds ratioPlaque ruptureParasympathetic withdrawalHemodynamic monitor
2010
Tendency to Angry Rumination Predicts Stress-Provoked Endothelin-1 Increase in Patients With Coronary Artery Disease
Fernandez AB, Soufer R, Collins D, Soufer A, Ranjbaran H, Burg MM. Tendency to Angry Rumination Predicts Stress-Provoked Endothelin-1 Increase in Patients With Coronary Artery Disease. Psychosomatic Medicine 2010, 72: 348-353. PMID: 20368479, PMCID: PMC2872076, DOI: 10.1097/psy.0b013e3181d71982.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseET-1 increaseET-1Chronic stable coronary heart diseaseStable coronary heart diseaseMultivariate logistic regression modelET-1 elevationAcute coronary syndromeHistory of diabetesRate-pressure productCoronary artery diseaseEndothelin-1 increaseLogistic regression modelsCoronary syndromeArtery diseaseBeta blockersPotential confoundersPressure productHeart diseasePlaque ruptureBlood samplesPatientsAngry ruminationNitric oxideStress protocol
2001
Depression in chronic medical illness: The case of coronary heart disease
Burg M, Abrams D. Depression in chronic medical illness: The case of coronary heart disease. Journal Of Clinical Psychology 2001, 57: 1323-1337. PMID: 11590618, DOI: 10.1002/jclp.1100.Peer-Reviewed Original ResearchConceptsCoronary diseasePoor long-term psychosocial outcomesLong-term psychosocial outcomesChronic medical illnessCoronary heart diseasePost-MI patientsPrevious cardiac historyCAD severityCardiac historyMedical illnessMyocardial infarctionHeart diseaseReporting symptomsMinor depressionMajor depressionCase reviewPsychosocial outcomesPatientsDepressionDiseaseImportant predictorMorbidityInfarctionIllnessSymptomsDay-to-day reproducibility of mental stress-induced abnormal left ventricular function response in patients with coronary artery disease and its relationship to autonomic activation
Jain D, Joska T, Lee F, Burg M, Lampert R, Zaret B. Day-to-day reproducibility of mental stress-induced abnormal left ventricular function response in patients with coronary artery disease and its relationship to autonomic activation. Journal Of Nuclear Cardiology 2001, 8: 347-355. PMID: 11391305, DOI: 10.1067/mnc.2001.113517.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseSystolic blood pressureLV ejection fractionLV dysfunctionRate-pressure productBlood pressureAnger recallMS taskHeart rate variabilityAutonomic activationLVEF responseArtery diseaseMental stressSympathetic activationHeart rateSymptomatic coronary artery diseaseRate variabilityAbnormal LVEF responseVentricular function responseChronic stable anginaExercise-induced ischemiaLeft ventricular dysfunctionAdverse prognostic signLF/HFCardiac medications
1998
Effects of Mental Stress on Left Ventricular and Peripheral Vascular Performance in Patients With Coronary Artery Disease
Jain D, Shaker M, Burg M, Wackers F, Soufer R, Zaret B. Effects of Mental Stress on Left Ventricular and Peripheral Vascular Performance in Patients With Coronary Artery Disease. Journal Of The American College Of Cardiology 1998, 31: 1314-1322. PMID: 9581726, DOI: 10.1016/s0735-1097(98)00092-8.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionPeripheral vascular resistanceCoronary artery diseaseRate-pressure productStress-induced fallSystolic blood pressureArtery diseaseBlood pressureCardiac outputHeart rateMental stressGroup IHemodynamic variablesAnger recallGroup IIMental stressorsEnd-systolic ventricular elastanceMental stress-induced changesSemisupine bicycle exerciseGroup II patientsComparable increaseDiastolic blood pressureVentricular ejection fractionExercise-induced changesVascular resistance
1995
Prognostic Implications of Mental Stress-Induced Silent Loft Ventricular Dysfunction in Patients With Stable Angina Pectoris
Jain D, Burg M, Soufer R, Zaret B. Prognostic Implications of Mental Stress-Induced Silent Loft Ventricular Dysfunction in Patients With Stable Angina Pectoris. The American Journal Of Cardiology 1995, 76: 31-35. PMID: 7793399, DOI: 10.1016/s0002-9149(99)80796-6.Peer-Reviewed Original ResearchConceptsStable angina pectorisTransient LV dysfunctionAdverse cardiac eventsCardiac eventsLV dysfunctionAngina pectorisMental stressAbnormal cardiovascular reactivityHigher cardiac eventsCohort of patientsCoronary artery diseaseGroup of patientsVentricular function monitoringMental arithmeticVentricular dysfunctionAdverse eventsBaseline characteristicsBeta blockersContinuous ambulatoryArtery diseaseRisk stratificationPrognostic implicationsStress perfusionFunction monitoringHeart rate
1993
Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease
Burg M, Jain D, Soufer R, Kerns R, Zaret B. Role of behavioral and psychological factors in mental stress-induced silent left ventricular dysfunction in coronary artery disease. Journal Of The American College Of Cardiology 1993, 22: 440-448. PMID: 8335813, DOI: 10.1016/0735-1097(93)90048-6.Peer-Reviewed Original ResearchConceptsSilent left ventricular dysfunctionLeft ventricular dysfunctionCoronary artery diseaseVentricular dysfunctionArtery diseaseBlood pressureChronic stable coronary artery diseaseStable coronary artery diseaseStress thallium-201 imagingMental stressGroup I patientsSilent myocardial ischemiaThallium-201 imagingAbsence of symptomsSerial radionuclide ventriculographyStructured interviewsNonischemic groupEjection fractionI patientsPsychological factorsVentricular indexRadionuclide ventriculographyClinical indicesMyocardial ischemiaReversible defects
1989
Cynical Mistrust and the search for self-worth
Fontana A, Kerns R, Blatt S, Rosenberg R, Burg M, Colonese K. Cynical Mistrust and the search for self-worth. Journal Of Psychosomatic Research 1989, 33: 449-456. PMID: 2795517, DOI: 10.1016/0022-3999(89)90006-8.Peer-Reviewed Original Research
1987
Psychological correlates of hostility among patients undergoing coronary angiography
Blumenthal J, Barefoot J, Burg M, Williams R. Psychological correlates of hostility among patients undergoing coronary angiography. Psychology And Psychotherapy Theory Research And Practice 1987, 60: 349-355. PMID: 3426973, DOI: 10.1111/j.2044-8341.1987.tb02754.x.Peer-Reviewed Original ResearchConceptsState-Trait Personality InventoryPerceived Social Support ScaleMinnesota Multiphasic Personality InventoryHo scalePersonality InventoryIneffective coping stylesSelf-Rating InventoryCook-Medley Hostility ScaleSelf-report questionnairesPattern of correlationsSocial Support ScaleHopkins Symptom Check ListCoronary heart diseasePsychological correlatesMultiphasic Personality InventoryCoping stylesPsychological dimensionsSymptom Check ListPsychosocial correlatesSocial maladjustmentBehavioral dimensionsPsychometric instrumentsSupport ScaleHostility ScaleCoronary angiographySocial support, type A behavior, and coronary artery disease.
Blumenthal J, Burg M, Barefoot J, Williams R, Haney T, Zimet G. Social support, type A behavior, and coronary artery disease. Psychosomatic Medicine 1987, 49: 331-340. PMID: 3615762, DOI: 10.1097/00006842-198707000-00002.Peer-Reviewed Original ResearchConceptsPerceived Social Support ScaleCoronary artery disease severitySocial supportLong-term health consequencesDiagnostic coronary angiographyCoronary artery diseaseType A structured interviewStructured interviewsSevere CADArtery diseaseCoronary angiographySignificant CADType A behavior patternA behavior patternDisease severityHealth consequencesSocial Support ScaleType BsPsychometric testsSupport ScaleSocial support interactionsLow levelsHigh levelsPatientsAngiography