2022
Dietary adaptation for weight loss maintenance at Yale (DAWLY): Protocol and predictions for a randomized controlled trial
Fang X, Davis X, Flack KD, Duncan C, Li F, White M, Grilo C, Small DM. Dietary adaptation for weight loss maintenance at Yale (DAWLY): Protocol and predictions for a randomized controlled trial. Frontiers In Nutrition 2022, 9: 940064. PMID: 35967820, PMCID: PMC9369668, DOI: 10.3389/fnut.2022.940064.Peer-Reviewed Original ResearchWeight loss maintenanceHigh-fat dietWeight loss treatmentLoss maintenanceWeight lossLoss treatmentStandard behavioral weight loss treatmentShort-term weight lossBehavioral weight loss interventionBehavioral weight loss treatmentGut-brain pathwaysPlacebo-controlled trialGut-brain axisVagal afferent pathwaysGut-brain signalingDietary fat intakeOverweight/obesityWeight loss interventionPrecision medicine approachEnergy-dense foodsLoss interventionFat intakeAfferent pathwaysHabitual intakeMetabolic health
2021
Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder
Grilo CM, Kerrigan SG, Lydecker JA, White MA. Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder. Obesity 2021, 29: 2026-2034. PMID: 34582624, PMCID: PMC8612949, DOI: 10.1002/oby.23278.Peer-Reviewed Original ResearchConceptsBehavioral weight loss treatmentWeight loss treatmentLatinx patientsPhysical activity changesBWL treatmentReduced depressionCommunity mental health centerWeight lossPA changePlacebo-controlled trialAddition of orlistatMental health centersActivity changesPrognostic significanceMedication conditionHealth centersLoss treatmentPatientsObesitySecondary analysisClinical settingBed statusBaselineTreatmentDepression
2014
Treatment of binge eating disorder in racially and ethnically diverse obese patients in primary care: Randomized placebo-controlled clinical trial of self-help and medication
Grilo CM, Masheb RM, White MA, Gueorguieva R, Barnes RD, Walsh BT, McKenzie KC, Genao I, Garcia R. Treatment of binge eating disorder in racially and ethnically diverse obese patients in primary care: Randomized placebo-controlled clinical trial of self-help and medication. Behaviour Research And Therapy 2014, 58: 1-9. PMID: 24857821, PMCID: PMC4074556, DOI: 10.1016/j.brat.2014.04.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAnti-Obesity AgentsBinge-Eating DisorderBlack or African AmericanBody WeightCognitive Behavioral TherapyCombined Modality TherapyCyclobutanesDouble-Blind MethodFemaleHispanic or LatinoHumansMaleMiddle AgedObesityPrimary Health CareSelf CareTime FactorsTreatment OutcomeWhite PeopleYoung AdultConceptsSelf-help cognitive behavioral therapyDiverse obese patientsAnti-obesity medicationsObese patientsModerate clinical outcomePercent weight lossTime interaction effectsWeight lossClinical outcomesPrimary careRandomized placebo-controlled clinical trialSecond placebo-controlled trialPlacebo-controlled clinical trialAcute weight lossPlacebo-controlled trialDouble-blind fashionDiscontinuation of medicationPrimary care settingWeight loss maintenanceSpecialist treatment centresTreatment of bingeDiverse patient groupsSelf-help CBTBinge-eating frequencyDemographic factors
2013
Bupropion for overweight women with binge-eating disorder: a randomized, double-blind, placebo-controlled trial.
White MA, Grilo CM. Bupropion for overweight women with binge-eating disorder: a randomized, double-blind, placebo-controlled trial. The Journal Of Clinical Psychiatry 2013, 74: 400-6. PMID: 23656848, PMCID: PMC4021866, DOI: 10.4088/jcp.12m08071.Peer-Reviewed Original ResearchConceptsBinge-eating disorderPlacebo-controlled trialObese womenOutcome measuresWeight lossDSM-IV-TR research criteriaTreatment of BEDInappropriate weight compensatory behaviorsRandomized placebo-controlled trialShort-term weight lossFood cravingsPercent BMI lossSecondary outcome measuresPrimary outcome measureShort-term efficacyTerm weight lossBinge-eating frequencySignificant time effectStand-alone treatmentLong-term trialsBMI lossPlacebo groupLifestyle interventionOverweight womenRandomized participantsOrlistat with behavioral weight loss for obesity with versus without binge eating disorder: Randomized placebo-controlled trial at a community mental health center serving educationally and economically disadvantaged Latino/as
Grilo CM, White MA. Orlistat with behavioral weight loss for obesity with versus without binge eating disorder: Randomized placebo-controlled trial at a community mental health center serving educationally and economically disadvantaged Latino/as. Behaviour Research And Therapy 2013, 51: 167-175. PMID: 23376451, PMCID: PMC3666334, DOI: 10.1016/j.brat.2013.01.002.Peer-Reviewed Original ResearchConceptsCommunity mental health centerMental health centersPlacebo-controlled trialBehavioral weight lossAddition of orlistatHealth centersRandomized placebo-controlled trialTreatment studiesWeight lossComplex patient groupNon-BED groupObesity Treatment StudyNegative prognostic indicatorHigh rateModerate treatment outcomeRemission rateObese patientsPlacebo medicationDiabetes preventionMixed-model analysisPatient groupObesity treatmentPrognostic indicatorTreatment outcomesEfficacy trials
2010
Negative weight-based attitudes in treatment-seeking obese monolingual Hispanic patients with and without binge eating disorder
Puhl RM, White MA, Paris M, Anez LM, Silva MA, Grilo CM. Negative weight-based attitudes in treatment-seeking obese monolingual Hispanic patients with and without binge eating disorder. Comprehensive Psychiatry 2010, 52: 737-743. PMID: 21193178, PMCID: PMC3131447, DOI: 10.1016/j.comppsych.2010.11.006.Peer-Reviewed Original ResearchConceptsDisorder psychopathologyNegative attitudesSample of EnglishPsychological functioningBody imageMonolingual SpanishCommunity mental health centerLatina groupsMental health centersPsychopathologyResearch cliniciansSemistructured interviewsBingeObese LatinosAttitudesRandomized placebo-controlled trialPlacebo-controlled trialLatino adultsParticipantsHispanic patientsConsecutive seriesDisordersObese personsHealth centersFunctioning