2021
The Other Side of Triage: When Access to Intensive Care Measures May Do More Harm than Good
Feder KJ, Zaidi D, Siegel MD. The Other Side of Triage: When Access to Intensive Care Measures May Do More Harm than Good. The American Journal Of Bioethics 2021, 21: 79-82. PMID: 34710018, DOI: 10.1080/15265161.2021.1980136.Peer-Reviewed Original Research
2020
Making Medical Treatment Decisions for Unrepresented Patients in the ICU. An Official American Thoracic Society/American Geriatrics Society Policy Statement
Pope TM, Bennett J, Carson SS, Cederquist L, Cohen AB, DeMartino ES, Godfrey DM, Goodman-Crews P, Kapp MB, Lo B, Magnus DC, Reinke LF, Shirley JL, Siegel MD, Stapleton RD, Sudore RL, Tarzian AJ, Thornton JD, Wicclair MR, Widera EW, White DB. Making Medical Treatment Decisions for Unrepresented Patients in the ICU. An Official American Thoracic Society/American Geriatrics Society Policy Statement. American Journal Of Respiratory And Critical Care Medicine 2020, 201: 1182-1192. PMID: 32412853, PMCID: PMC7233335, DOI: 10.1164/rccm.202003-0512st.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsUnrepresented patientsFair processProcedural due processMedical treatment decisionsPolicy statementsElder lawDue processHealth lawProcedural safeguardsState lawsUndue influenceLawCritical care settingAppropriate balanceAdvance directivesEthical goalsTreatment decisionsAppropriate medical careDiligent searchCapacity assessmentPatient advocacyInstitutionsPolicy recommendationsLess oversightCare settings
2015
Critical Care at the End of Life
Akgün KM, Kapo JM, Siegel MD. Critical Care at the End of Life. Seminars In Respiratory And Critical Care Medicine 2015, 36: 921-933. PMID: 26600274, DOI: 10.1055/s-0035-1565254.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsCommunicationCritical CareHumansIntensive Care UnitsPalliative CarePractice Guidelines as TopicTerminal CareConceptsPalliative care skillsPalliative care modelCare modelCare skillsBasic palliative care skillsComplex palliative care needsIntensive care unit admissionCare unit admissionPalliative care consultationPalliative care needsPalliative care domainsChronic life-limiting conditionsFamily-centered endLife-limiting conditionsPeer support groupsUnit admissionEnd of lifeICU patientsSymptom managementCare consultationsICU providersCritical careIndividual ICUsICUCare needs
2012
Using standardized family members to teach end-of-life skills to critical care trainees*
Akgün KM, Siegel MD. Using standardized family members to teach end-of-life skills to critical care trainees*. Critical Care Medicine 2012, 40: 1978-1980. PMID: 22610211, DOI: 10.1097/ccm.0b013e3182536cd1.Peer-Reviewed Original ResearchAdapting To the New Consensus Guidelines for Managing Hyperglycemia During Critical Illness: the Updated Yale Insulin Infusion Protocol
Shetty S, Inzucchi SE, Goldberg PA, Cooper D, Siegel MD, Honiden S. Adapting To the New Consensus Guidelines for Managing Hyperglycemia During Critical Illness: the Updated Yale Insulin Infusion Protocol. Endocrine Practice 2012, 18: 363-370. PMID: 22138078, DOI: 10.4158/ep11260.or.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood GlucoseCohort StudiesConnecticutCritical CareDiabetes MellitusDrug MonitoringFemaleHealth Plan ImplementationHumansHyperglycemiaHypoglycemiaHypoglycemic AgentsInfusions, IntravenousInsulin, Regular, HumanMaleMiddle AgedPractice Guidelines as TopicProspective StudiesTime FactorsConceptsYale Insulin Infusion ProtocolInsulin infusion protocolBlood glucose concentrationIntensive care unitBlood glucose valuesInsulin infusionInfusion protocolChronic Health Evaluation II scoreGlucose valuesMedical intensive care unitGlucose concentrationAdmission Acute PhysiologyUse of vasopressorsBlood glucose targetsContinuous venovenous hemodialysisIntravenous dextrose infusionBlood glucose controlBaseline blood glucose concentrationRecent national guidelinesNew consensus guidelinesInsulin infusion rateAcute PhysiologyIntravenous dextroseII scoreMedian durationWithin the black box
Siegel MD, Perez MT. Within the black box. Critical Care Medicine 2012, 40: 1339-1340. PMID: 22425829, DOI: 10.1097/ccm.0b013e3182451b76.Peer-Reviewed Original Research
2011
Success Stories: Use of Patient Vignettes to Assess the Ability of Physicians to Predict Extubation Success
Siner JM, Siegel MD. Success Stories: Use of Patient Vignettes to Assess the Ability of Physicians to Predict Extubation Success. Respiratory Care 2011, 56: 1050-1051. PMID: 21740729, DOI: 10.4187/respcare.01438.Commentaries, Editorials and LettersDiagnosis and Management of Life-Threatening Pulmonary Embolism
Marshall PS, Mathews KS, Siegel MD. Diagnosis and Management of Life-Threatening Pulmonary Embolism. Journal Of Intensive Care Medicine 2011, 26: 275-294. PMID: 21606060, DOI: 10.1177/0885066610392658.Peer-Reviewed Original ResearchConceptsMassive pulmonary embolusDiagnosis of PECatheter-based therapiesPulmonary emboliTomographic pulmonary angiographySurgical embolectomyThrombolytic therapyPoor outcomePulmonary angiographyLife-threatening pulmonary emboliLife-Threatening Pulmonary EmbolismLower extremity Doppler ultrasoundInferior vena cava filterComplicated hospital courseImproved pulmonary perfusionPulmonary artery vasodilatorsRecurrent pulmonary emboliRight ventricular dysfunctionUse of vasopressorsBrain natriuretic peptidePresence of hypotensionLife-threatening hemorrhageChoice of treatmentCatheter-based interventionsVena cava filters
2009
Routine daily vs on-demand chest radiographs in intensive care
Siegel MD, Rubinowitz AN. Routine daily vs on-demand chest radiographs in intensive care. The Lancet 2009, 374: 1656-1658. PMID: 19896185, DOI: 10.1016/s0140-6736(09)61632-9.Peer-Reviewed Original ResearchELEVATED SERUM ANGIOPOIETIN 2 LEVELS ARE ASSOCIATED WITH INCREASED MORTALITY IN SEPSIS
Siner JM, Bhandari V, Engle KM, Elias JA, Siegel MD. ELEVATED SERUM ANGIOPOIETIN 2 LEVELS ARE ASSOCIATED WITH INCREASED MORTALITY IN SEPSIS. Shock 2009, 31: 348-353. PMID: 18791490, DOI: 10.1097/shk.0b013e318188bd06.Peer-Reviewed Original ResearchConceptsAng-2 levelsIntensive care unitAng-2Tertiary care medical intensive care unitProspective observational cohort studySerum Ang-2 levelsSerum angiopoietin-2 levelsMedical intensive care unitSerum Ang-2Observational cohort studyAngiopoietin-2 levelsIL-6 levelsHospital mortalityHuman sepsisICU admissionSevere sepsisCohort studyEndothelial dysfunctionHospital dischargeICU patientsIllness scoresSeptic shockCare unitIL-6Increased Mortality