2022
Epidemiology and outcomes of surgical site infections among pediatric liver transplant recipients
Banach DB, Lopez‐Verdugo F, Sanchez‐Garcia J, Tran A, Gomez‐Llerena A, Munoz‐Abraham A, Bertacco A, Valentino PL, Yoo P, Dembry L, Mulligan DC, Ekong UD, Emre SH, Rodriguez‐Davalos M. Epidemiology and outcomes of surgical site infections among pediatric liver transplant recipients. Transplant Infectious Disease 2022, 24: e13941. PMID: 35989545, DOI: 10.1111/tid.13941.Peer-Reviewed Original ResearchConceptsSurgical site infectionLiver transplant recipientsLiver transplantationBiliary complicationsGraft recipientsTransplant recipientsSite infectionRisk factorsOutcomes of SSIPediatric liver transplant recipientsLong-term graftPediatric liver transplantationRetrospective descriptive analysisPrimary endpointHospital daysPatient agePediatric populationPatient survivalSignificant causeComplicationsPatientsRecipientsOutcomesInfectionIncidenceClinical outcomes following dalbavancin administration in patients with barriers to outpatient parenteral antimicrobial therapy
Tuan J, Kayani J, Fisher A, Kotansky B, Dembry L, Datta R. Clinical outcomes following dalbavancin administration in patients with barriers to outpatient parenteral antimicrobial therapy. Antimicrobial Stewardship & Healthcare Epidemiology 2022, 2: e83. PMID: 36483361, PMCID: PMC9726471, DOI: 10.1017/ash.2022.229.Peer-Reviewed Original ResearchDalbavancin administrationOutpatient parenteral antimicrobial therapyDose of dalbavancinMedian antibiotic durationSoft tissue infectionsParenteral antimicrobial therapyAntibiotic durationDeveloped hepatotoxicityClinical cureSeptic arthritisClinical outcomesAntimicrobial therapyPatientsAdministrationDaysEndocarditisArthritisBacteremiaOsteomyelitisHepatotoxicityTherapyDalbavancinInfectionDose
2021
Surveillance of adverse drug events associated with tocilizumab in hospitalized veterans with coronavirus disease 2019 (COVID-19) to inform patient safety and pandemic preparedness
Datta R, Barrett A, Burk M, Salone C, Au A, Cunningham F, Fisher A, Dembry LM, Akgün KM. Surveillance of adverse drug events associated with tocilizumab in hospitalized veterans with coronavirus disease 2019 (COVID-19) to inform patient safety and pandemic preparedness. Infection Control And Hospital Epidemiology 2021, 43: 1488-1491. PMID: 33985598, PMCID: PMC8160489, DOI: 10.1017/ice.2021.227.Peer-Reviewed Original Research
2020
Education needed to improve antimicrobial use during end-of-life care of older adults with advanced cancer: A cross-sectional survey
Datta R, Topal J, McManus D, Sanft T, Dembry LM, Morrison LJ, Quagliarello V, Juthani-Mehta M. Education needed to improve antimicrobial use during end-of-life care of older adults with advanced cancer: A cross-sectional survey. Palliative Medicine 2020, 35: 236-241. PMID: 32928066, DOI: 10.1177/0269216320956811.Peer-Reviewed Original ResearchConceptsEscalation of careAdvance care planningLife careAdvanced cancerCross-sectional surveyIntravenous antimicrobialsOlder adultsAntimicrobial useCare planningSingle-center cross-sectional surveyEducational interventionAdvance care plansRole of antimicrobialsClinical deteriorationPercent of respondentsAdverse eventsOral antimicrobialsMedicine subspecialistsCare plansInpatient medicineCareCancerPatientsAdultsSubspecialistsAntimicrobial Stewardship Optimization in the Emergency Department: The Effect of Multiplex Respiratory Pathogen Testing and Targeted Educational Intervention
Durant TJS, Kubilay NZ, Reynolds J, Tarabar AF, Dembry LM, Peaper DR. Antimicrobial Stewardship Optimization in the Emergency Department: The Effect of Multiplex Respiratory Pathogen Testing and Targeted Educational Intervention. The Journal Of Applied Laboratory Medicine 2020, 5: 1172-1183. PMID: 32918445, DOI: 10.1093/jalm/jfaa130.Peer-Reviewed Original ResearchConceptsAntibiotic prescription ratesEmergency departmentPrescription ratesAntibiotic prescriptionsED visitsRespiratory pathogen testingRespiratory tract infectionsAdult emergency departmentAntimicrobial treatment decisionsProvider-patient interactionsDetection of influenzaTargeted educational interventionsAntimicrobial stewardship educationOseltamivir prescriptionsASP interventionsTract infectionsInfluenza seasonIntervention cohortTreatment decisionsPatient engagementPatientsResult availabilityCohortEducational interventionStewardship education
2019
Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures
Datta R, Wang T, Zhu M, Dembry LM, Han L, Allore H, Quagliarello V, Juthani-Mehta M. Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures. Infection Control And Hospital Epidemiology 2019, 40: 470-472. PMID: 30821230, PMCID: PMC6482377, DOI: 10.1017/ice.2019.22.Peer-Reviewed Original ResearchConceptsUrinary tract infectionIncidence rate ratiosAdvanced cancer patientsAsymptomatic bacteriuriaCancer patientsAntimicrobial therapySymptomatic urinary tract infectionPotential urinary tract infectionTract infectionsInappropriate therapyAntimicrobial daysComfort measuresBacteriuriaCandiduriaCFU/mLPatientsTherapyRate ratioMLInfection
2016
Epidemiology of Clostridium difficile infection in hospitalized oncology patients
Chang GY, Dembry LM, Banach DB. Epidemiology of Clostridium difficile infection in hospitalized oncology patients. American Journal Of Infection Control 2016, 44: 1421-1423. PMID: 27287733, DOI: 10.1016/j.ajic.2016.04.210.Peer-Reviewed Original ResearchConceptsClostridium difficile infectionBlood transfusionDifficile infectionHistory of CDIΒ-lactam/β-lactamase inhibitorsBroad-spectrum antibiotic useHospitalized oncology patientsRecent blood transfusionCDI historyCDI riskOlder patientsOncology inpatientsΒ-lactamase inhibitorsOncology patientsPrior receiptRisk factorsAntibiotic useMultivariate analysisTransfusionPatientsInfectionEpidemiologyInpatientsMetronidazoleCephalosporins
2014
Clinical and Molecular Epidemiology of Pretransplant Vancomycin-Resistant Enterococci (VRE) Colonization Among Patients Who Undergo Liver Transplantation.
Banach D, Peaper D, Emre S, Fortune B, Dembry L. Clinical and Molecular Epidemiology of Pretransplant Vancomycin-Resistant Enterococci (VRE) Colonization Among Patients Who Undergo Liver Transplantation. Transplantation 2014, 98: 769. DOI: 10.1097/00007890-201407151-02627.Peer-Reviewed Original Research
2010
SHEA Guideline for Management of Healthcare Workers Who Are Infected with Hepatitis B Virus, Hepatitis C Virus, and/or Human Immunodeficiency Virus
Henderson DK, Dembry L, Fishman NO, Grady C, Lundstrom T, Palmore TN, Sepkowitz KA, Weber DJ. SHEA Guideline for Management of Healthcare Workers Who Are Infected with Hepatitis B Virus, Hepatitis C Virus, and/or Human Immunodeficiency Virus. Infection Control And Hospital Epidemiology 2010, 31: 203-232. PMID: 20088696, DOI: 10.1086/650298.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHepatitis C virusHepatitis B virusHealthcare providersImmunodeficiency virusC virusB virusHealthcare workersAppropriate infection control proceduresBloodborne pathogen infectionsViral load levelsInfection control proceduresExposure of patientsPatient care activitiesTransfer of bloodType of procedureInfected providersSHEA guidelinesInfectious syndromesPatient transmissionHealthcare EpidemiologyPatientsVirusUnrelated virusesBlood
2006
Life-Threatening Sepsis Caused by Burkholderia cepacia From Contaminated Intravenous Flush Solutions Prepared by a Compounding Pharmacy in Another State
Held MR, Begier EM, Beardsley DS, Browne FA, Martinello RA, Baltimore RS, McDonald LC, Jensen B, Hadler JL, Dembry LM. Life-Threatening Sepsis Caused by Burkholderia cepacia From Contaminated Intravenous Flush Solutions Prepared by a Compounding Pharmacy in Another State. Pediatrics 2006, 118: e212-e215. PMID: 16785290, DOI: 10.1542/peds.2005-2617.Peer-Reviewed Original ResearchConceptsBlood culturesOutside health care facilityBurkholderia cepacia sepsisLife-threatening casesLife-threatening sepsisPatient's blood culturesHealth care facilitiesInfusate contaminationPulsed-field gel electrophoresisFlush solutionCare facilitiesSafe deliverySepsisCompounding pharmaciesBacterial isolatesBurkholderia cepaciaMedicationsPatientsInfusate
2005
Recommended Modifications and Applications of the Hospital Emergency Incident Command System for Hospital Emergency Management
Arnold JL, Dembry LM, Tsai MC, Dainiak N, Rodoplu Ü, Schonfeld DJ, Parwani V, Paturas J, Cannon C, Selig S. Recommended Modifications and Applications of the Hospital Emergency Incident Command System for Hospital Emergency Management. Prehospital And Disaster Medicine 2005, 20: 290-300. PMID: 16295165, DOI: 10.1017/s1049023x00002740.Peer-Reviewed Original ResearchConceptsHospital emergency managementHospital healthcare workersHealthcare workersHospital Emergency Incident Command SystemMental health needsHospital emergency responseHealth needsSevere acute respiratory syndrome (SARS) outbreakSignificant mental health needsTypes of patientsRespiratory syndrome outbreakMental health supportTokyo subway sarin attackInfectious patientsFurther experiencePatientsHealth supportResource-deficient settingsHealthcare systemUnit leadersSpecial proficiencyEmergency managementIncident Command SystemSarin attackEmergency
2004
Reasons physicians accepted or declined smallpox vaccine, February through April, 2003
Benin AL, Dembry L, Shapiro ED, Holmboe ES. Reasons physicians accepted or declined smallpox vaccine, February through April, 2003. Journal Of General Internal Medicine 2004, 19: 85-89. PMID: 14748865, PMCID: PMC1494683, DOI: 10.1111/j.1525-1497.2004.36005.x.Peer-Reviewed Original Research
1999
Management of a Sabiá Virus-Infected Patient in a US Hospital
Armstrong L, Dembry L, Rainey P, Russi M, Khan A, Fischer S, Edberg S, Ksiazek T, Rollin P, Peters CJ. Management of a Sabiá Virus-Infected Patient in a US Hospital. Infection Control And Hospital Epidemiology 1999, 20: 176-182. PMID: 10100543, DOI: 10.1086/501607.Peer-Reviewed Original ResearchConceptsIsolation precautionsUS hospitalsViral hemorrhagic fever patientsUniversity-affiliated medical centerVirus-infected patientsLocal hospital settingLaboratory-acquired infectionsPatient care settingsEnhanced precautionsNosocomial transmissionEarly diseaseFever patientsVirus antibodiesHealthcare workersSecondary casesVirus infectionMedical CenterHospital settingSecondary infectionLocal hospitalPatientsHospital staffAerosol spreadSabiá virusClinical specimens
1998
Molecular Analysis of Glycopeptide-ResistantEnterococcus faecium Isolates Collected from Michigan Hospitals over a 6-Year Period
Thal L, Donabedian S, Robinson-Dunn B, Chow J, Dembry L, Clewell D, Alshab D, Zervos M. Molecular Analysis of Glycopeptide-ResistantEnterococcus faecium Isolates Collected from Michigan Hospitals over a 6-Year Period. Journal Of Clinical Microbiology 1998, 36: 3303-3308. PMID: 9774583, PMCID: PMC105319, DOI: 10.1128/jcm.36.11.3303-3308.1998.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsBacterial Typing TechniquesChromosomes, BacterialCross InfectionDNA, BacterialDrug Resistance, MicrobialElectrophoresis, Gel, Pulsed-FieldEnterococcus faeciumGene Transfer TechniquesGenes, BacterialGram-Positive Bacterial InfectionsHumansMichiganMolecular EpidemiologyNucleic Acid HybridizationPlasmidsVancomycinConceptsExtended-care facilityPulsed-field gel electrophoresisEnterococcus faecium isolatesFaecium isolatesClonal disseminationVancomycin-resistant E. faeciumStrain typesE. faecium isolatesVancomycin-resistant E. faecium isolatesIntrahospital disseminationSpread of resistanceMichigan hospitalsMajority of isolatesPatientsHospitalClinical isolatesGentamicin resistanceVanA geneErythromycin resistanceE. faeciumVancomycin resistanceType M2VanB genesMolecular relatednessMost isolatesNosocomial Candida glabrata Colonization: an Epidemiologic Study
Vazquez J, Dembry L, Sanchez V, Vazquez M, Sobel J, Dmuchowski C, Zervos M. Nosocomial Candida glabrata Colonization: an Epidemiologic Study. Journal Of Clinical Microbiology 1998, 36: 421-426. PMID: 9466752, PMCID: PMC104553, DOI: 10.1128/jcm.36.2.421-426.1998.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBone Marrow TransplantationCandidaCandidiasisChildChild, PreschoolCross InfectionDNA, FungalEnvironmental MicrobiologyFemaleHandHealth PersonnelHospitalizationHospitals, UniversityHumansIntensive Care UnitsMaleMiddle AgedMolecular EpidemiologyPolymorphism, Restriction Fragment LengthProspective StudiesRisk FactorsConceptsNosocomial acquisitionC. glabrataMedical intensive care unitBone marrow transplant unitPrior antimicrobial useDuration of hospitalizationIntensive care unitMarrow transplant unitSignificant risk factorsImportant nosocomial pathogenStrain typesSame strain typeCare unitTransplant unitUniversity HospitalRisk factorsEpidemiologic studiesPatientsC. glabrata strainsEnvironmental surfacesHospital personnelNosocomial pathogenAntimicrobial useIdentical strainsHospital environmentNosocomial Bacterial Infections
Dembry L, Zervos M, Hierholzer W. Nosocomial Bacterial Infections. 1998, 501-528. DOI: 10.1007/978-1-4615-5327-4_26.Peer-Reviewed Original ResearchNosocomial infectionsWorld Health OrganizationCertain nosocomial infectionsNosocomial bacterial infectionsPrevious admissionsBacterial etiologyPrevalence studyHealth care institutionsBacterial infectionsInfectionPatientsAdmissionHealth OrganizationCare institutionsSignificant numberNosocomialEtiology
1996
Control of Endemic Glycopeptide-Resistant Enterococci
Dembry L, Uzokwe K, Zervos M. Control of Endemic Glycopeptide-Resistant Enterococci. Infection Control And Hospital Epidemiology 1996, 17: 286-292. DOI: 10.2307/30141928.Peer-Reviewed Original ResearchVancomycin-resistant EnterococcusRenal unitsEradication of carriageVRE stool colonizationCommunity teaching hospitalPatient carriageBarrier precautionsOral doxycyclineFurther patientsStool colonizationGlycopeptide-resistant enterococciCulture surveyTeaching hospitalPatientsStudy periodEnterococcus faeciumEnterococcus gallinarumEnterococcus faecalisCarriageRifampinDoxycyclineEnterococcusControl measuresDaysUseful measureControl of endemic glycopeptide-resistant enterococci.
Dembry LM, Uzokwe K, Zervos MJ. Control of endemic glycopeptide-resistant enterococci. Infection Control And Hospital Epidemiology 1996, 17: 286-92. PMID: 8727617, DOI: 10.1086/647297.Peer-Reviewed Original ResearchConceptsVancomycin-resistant EnterococcusRenal unitsEradication of carriageVRE stool colonizationCommunity teaching hospitalPatient carriageBarrier precautionsOral doxycyclineFurther patientsStool colonizationGlycopeptide-resistant enterococciCulture surveyTeaching hospitalPatientsStudy periodEnterococcus faeciumEnterococcus gallinarumCarriageRifampinDoxycyclineEnterococcusControl measuresDaysUseful measureHospital
1994
DNA Analysis in the Study of the Epidemiology of Nosocomial Candidiasis
Dembry L, Vazquez J, Zervos M. DNA Analysis in the Study of the Epidemiology of Nosocomial Candidiasis. Infection Control And Hospital Epidemiology 1994, 15: 48-54. DOI: 10.2307/30148385.Peer-Reviewed Original ResearchConceptsCandida infectionsCandida speciesIntensive supportive careLonger patient survivalCurrent therapeutic regimensDisseminated Candida infectionFemale genital tractSevere Candida infectionsCandida albicans fungemiaImportant nosocomial pathogenNosocomial candidiasisAggressive treatmentPostoperative patientsSupportive careCrude mortalityIntensive carePatient survivalTherapeutic regimensCancer patientsBlood culturesGenital tractGastrointestinal tractViral infectionPatientsNosocomial pathogen
1993
Nosocomial Acquisition of Candida albicans: An Epidemiologic Study
Vazquez J, Sanchez V, Dmuchowski C, Dembry L, Sobel J, Zervos M. Nosocomial Acquisition of Candida albicans: An Epidemiologic Study. The Journal Of Infectious Diseases 1993, 168: 195-201. PMID: 8515108, DOI: 10.1093/infdis/168.1.195.Peer-Reviewed Original ResearchConceptsNosocomial acquisitionMedical intensive care unitBone marrow transplant unitIntensive care unitMarrow transplant unitIndirect patient contactC. albicansPrior antibioticsCare unitProspective studyTransplant unitUniversity HospitalRisk factorsEpidemiologic studiesPatient contactPatientsEnvironmental surfacesHospital personnelCandida albicansIdentical strainsStrain typesAdmissionLength of timeRestriction enzyme analysisAlbicans