2013
Distinct associations of insula and cingulate volume with the cognitive and affective dimensions of alexithymia
Goerlich-Dobre K, Bruce L, Martens S, Aleman A, Hooker C. Distinct associations of insula and cingulate volume with the cognitive and affective dimensions of alexithymia. Neuropsychologia 2013, 53: 284-292. PMID: 24334109, DOI: 10.1016/j.neuropsychologia.2013.12.006.Peer-Reviewed Original ResearchConceptsBermond-Vorst Alexithymia QuestionnaireAffective alexithymia dimensionAlexithymia dimensionsLarger gray matter volumeGray matter volumeVoxel-based morphometryAffective dimensionsMatter volumeSpecific neural basisSubjective emotional experienceLower emotional reactivityDistinct structural correlatesRight posterior insulaToronto Alexithymia ScaleCognitive controlNeural correlatesNeural basisEmotional reactivityEmotional experienceAffect dysregulationAlexithymia QuestionnaireCognitive dimensionsAlexithymia ScalePosterior insulaTAS-20
2011
Theory of Mind Skills Are Related to Gray Matter Volume in the Ventromedial Prefrontal Cortex in Schizophrenia
Hooker C, Bruce L, Lincoln S, Fisher M, Vinogradov S. Theory of Mind Skills Are Related to Gray Matter Volume in the Ventromedial Prefrontal Cortex in Schizophrenia. Biological Psychiatry 2011, 70: 1169-1178. PMID: 21917239, PMCID: PMC3432316, DOI: 10.1016/j.biopsych.2011.07.027.Peer-Reviewed Original ResearchConceptsVentromedial prefrontal cortexGray matter volumeToM processingToM skillsSchizophrenia participantsMind skillsGlobal cognitionPrefrontal cortexHealthy participantsWorse ToM performanceGeneral cognitive deficitsStandardized neuropsychological measuresPoor social functioningMatter volumeToM performanceNeural basisNeuropsychological measuresVmPFC functionVoxel-based morphometrySocial functioningCognitive deficitsSocial outcomesBetween-group analysisBehavioral assessmentToM