2013
The influence of combined cognitive plus social-cognitive training on amygdala response during face emotion recognition in schizophrenia
Hooker C, Bruce L, Fisher M, Verosky S, Miyakawa A, D'Esposito M, Vinogradov S. The influence of combined cognitive plus social-cognitive training on amygdala response during face emotion recognition in schizophrenia. Psychiatry Research 2013, 213: 99-107. PMID: 23746615, PMCID: PMC6999046, DOI: 10.1016/j.pscychresns.2013.04.001.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAmygdalaCognitive Behavioral TherapyEmotionsFacial ExpressionFemaleFunctional LateralityFunctional NeuroimagingHumansMagnetic Resonance ImagingMaleMiddle AgedPrefrontal CortexPutamenSchizophreniaSchizophrenic PsychologySocial BehaviorSocial PerceptionTherapy, Computer-AssistedTreatment OutcomeVideo GamesConceptsSocial cognition trainingSocial cognitive trainingAuditory-based cognitive trainingNeural activity increasesEmotion recognitionBehavioral improvementFunctional magnetic resonance imaging (fMRI) taskSocial cognition skillsSocial cognitive deficitsCognitive remediation studiesFace emotion recognitionFacial emotion recognitionRight medial prefrontal cortexComputer-based interventionsComputer gamesMedial prefrontal cortexEmotion perceptionCognitive trainingSocial cognitionAmygdala responseFMRI resultsSchizophrenia participantsBehavioral performanceBehavioral gainsNeural mechanisms
2012
Neural activity during emotion recognition after combined cognitive plus social cognitive training in schizophrenia
Hooker C, Bruce L, Fisher M, Verosky S, Miyakawa A, Vinogradov S. Neural activity during emotion recognition after combined cognitive plus social cognitive training in schizophrenia. Schizophrenia Research 2012, 139: 53-59. PMID: 22695257, PMCID: PMC4346150, DOI: 10.1016/j.schres.2012.05.009.Peer-Reviewed Original ResearchConceptsSocial cognition trainingAuditory-based cognitive trainingSocial cognitive trainingCognitive remediation trainingEmotion recognitionCognitive trainingCognition trainingRemediation trainingSocial cognitionEmotion processingNeural mechanismsBehavioral improvementComputer gamesSocial cognition skillsSocial cognitive deficitsFacial emotion recognitionIntervention-related improvementsStandard behavioral assessmentsCognition skillsPost-intervention increaseFMRI taskNegative emotionsGeneral cognitionRemediation interventionsFMRI results
2011
Theory of Mind Skills Are Related to Gray Matter Volume in the Ventromedial Prefrontal Cortex in Schizophrenia
Hooker C, Bruce L, Lincoln S, Fisher M, Vinogradov S. Theory of Mind Skills Are Related to Gray Matter Volume in the Ventromedial Prefrontal Cortex in Schizophrenia. Biological Psychiatry 2011, 70: 1169-1178. PMID: 21917239, PMCID: PMC3432316, DOI: 10.1016/j.biopsych.2011.07.027.Peer-Reviewed Original ResearchConceptsVentromedial prefrontal cortexGray matter volumeToM processingToM skillsSchizophrenia participantsMind skillsGlobal cognitionPrefrontal cortexHealthy participantsWorse ToM performanceGeneral cognitive deficitsStandardized neuropsychological measuresPoor social functioningMatter volumeToM performanceNeural basisNeuropsychological measuresVmPFC functionVoxel-based morphometrySocial functioningCognitive deficitsSocial outcomesBetween-group analysisBehavioral assessmentToMSocial anhedonia is associated with neural abnormalities during face emotion processing
Germine L, Garrido L, Bruce L, Hooker C. Social anhedonia is associated with neural abnormalities during face emotion processing. NeuroImage 2011, 58: 935-945. PMID: 21763435, DOI: 10.1016/j.neuroimage.2011.06.059.Peer-Reviewed Original ResearchConceptsFace emotion processingFunctional magnetic resonance imagingSocial anhedoniaEmotion processingEmotion discriminationNeural mechanismsSocial affiliationRostral medial prefrontal cortexLess neural activityRight superior temporal gyrusFace emotion recognitionEmotion recognition deficitsGroup × condition interactionEmotion processing regionsSuperior temporal gyrusPoor social outcomesMedial prefrontal cortexSocial cognitionRecognition deficitsEmotion recognitionNeural basisIndividual differencesSocial motivationProcessing regionsInterpersonal interactions