Theory of Mind Skills Are Related to Gray Matter Volume in the Ventromedial Prefrontal Cortex in Schizophrenia
Hooker C, Bruce L, Lincoln S, Fisher M, Vinogradov S. Theory of Mind Skills Are Related to Gray Matter Volume in the Ventromedial Prefrontal Cortex in Schizophrenia. Biological Psychiatry 2011, 70: 1169-1178. PMID: 21917239, PMCID: PMC3432316, DOI: 10.1016/j.biopsych.2011.07.027.Peer-Reviewed Original ResearchConceptsVentromedial prefrontal cortexGray matter volumeToM processingToM skillsSchizophrenia participantsMind skillsGlobal cognitionPrefrontal cortexHealthy participantsWorse ToM performanceGeneral cognitive deficitsStandardized neuropsychological measuresPoor social functioningMatter volumeToM performanceNeural basisNeuropsychological measuresVmPFC functionVoxel-based morphometrySocial functioningCognitive deficitsSocial outcomesBetween-group analysisBehavioral assessmentToM