2024
Household air pollution and risk of pulmonary tuberculosis in HIV-Infected adults
Katoto P, Bihehe D, Brand A, Mushi R, Kusinza A, Alwood B, van Zyl-Smit R, Tamuzi J, Sam-Agudu N, Yotebieng M, Metcalfe J, Theron G, Godri Pollitt K, Lesosky M, Vanoirbeek J, Mortimer K, Nawrot T, Nemery B, Nachega J. Household air pollution and risk of pulmonary tuberculosis in HIV-Infected adults. Environmental Health 2024, 23: 6. PMID: 38233832, PMCID: PMC10792790, DOI: 10.1186/s12940-023-01044-0.Peer-Reviewed Original ResearchConceptsRisk of pulmonary tuberculosisPulmonary tuberculosisHousehold air pollutionHIV infectionTB-HIV coinfectionHIV-infected adultsAssociated with increased riskCase-control studyMultivariate logistic regressionHAP exposureDose-dependentlyPersonal CO exposuresPersonal carbon monoxidePTB riskLowest quintileCo-exposureHighest quintileBackgroundIn low-Logistic regressionRandom sub-sampleEffective interventionsHIVTuberculosisAir pollutionEastern Democratic Republic of CongoAssessment of wood smoke induced pulmonary toxicity in normal- and chronic bronchitis-like bronchial and alveolar lung mucosa models at air–liquid interface
Upadhyay S, Rahman M, Rinaldi S, Koelmel J, Lin E, Mahesh P, Beckers J, Johanson G, Pollitt K, Palmberg L, Irmler M, Ganguly K. Assessment of wood smoke induced pulmonary toxicity in normal- and chronic bronchitis-like bronchial and alveolar lung mucosa models at air–liquid interface. Respiratory Research 2024, 25: 49. PMID: 38245732, PMCID: PMC10799428, DOI: 10.1186/s12931-024-02686-5.Peer-Reviewed Original ResearchConceptsWood smokeBiomass fuel burningHuman primary bronchial epithelial cellsSecretion levels of proinflammatory cytokinesLevels of proinflammatory cytokinesPrimary bronchial epithelial cellsTumor necrosis factor-aAir-liquid interfacePrimary ciliary dyskinesiaHousehold air pollutionHighest increased riskBackgroundChronic obstructive pulmonary diseaseBronchial epithelial cellsChronic respiratory disordersPassive samplingToxicological end pointsAssociated with COPDExposed to WSObstructive pulmonary diseaseTobacco smoke exposureAir pollutionWS exposureExposure induced changesPulmonary toxicityAcute phase response
2022
Personal air pollutant exposure monitoring in South African children in the VHEMBE birth cohort
DeLay K, Lin EZ, Koelmel JP, Bornman R, Obida M, Chevrier J, Godri Pollitt KJ. Personal air pollutant exposure monitoring in South African children in the VHEMBE birth cohort. Environment International 2022, 170: 107524. PMID: 36260950, PMCID: PMC9982749, DOI: 10.1016/j.envint.2022.107524.Peer-Reviewed Original ResearchConceptsBirth cohortMalaria controlEnvironment (MACE) birth cohortVenda Health ExaminationEnvironmental exposuresBurden of diseaseIndoor residual sprayingSouth African childrenHousehold air pollutionMiddle-income countriesHealth examinationNon-invasive methodAfrican childrenPersonal exposure assessmentResidual sprayingExposure levelsPersonal exposureExposure assessmentExposure monitoringRural regionsChildrenHigh exposureEnvironmental contaminantsCohortExposure