2022
Derivation and validation of a predictive model for chronic stress in patients with cardiovascular disease
Malik AO, Jones PG, Mena-Hurtado C, Burg MM, Shishehbor MH, Hejjaji V, Tran A, Spertus JA, Smolderen KG. Derivation and validation of a predictive model for chronic stress in patients with cardiovascular disease. PLOS ONE 2022, 17: e0275729. PMID: 36256655, PMCID: PMC9578618, DOI: 10.1371/journal.pone.0275729.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiovascular DiseasesCohort StudiesFemaleHumansMaleMiddle AgedMyocardial InfarctionPeripheral Arterial DiseaseRegistriesRisk FactorsConceptsPeripheral artery diseaseCardiovascular diseaseChronic stressWorse outcomesSymptomatic peripheral artery diseaseMyocardial Infarction RegistryLogistic regression modelsPAD patientsProspective registryCurrent smokingArtery diseaseClinical factorsDerivation cohortValidation cohortC-statisticFemale sexPerceived Stress ScalePatientsEconomic burdenMedical careInstrument scoresSocioeconomic statusPotential targetDiseasePSS-4 scoresThe Yale Roadmap for Health Psychology and Integrated Cardiovascular Care
Gaffey AE, Harris KM, Mena-Hurtado C, Sinha R, Jacoby DL, Smolderen KG. The Yale Roadmap for Health Psychology and Integrated Cardiovascular Care. Health Psychology 2022, 41: 779-791. PMID: 35201804, DOI: 10.1037/hea0001152.Peer-Reviewed Original ResearchMeSH KeywordsBehavioral MedicineCardiovascular DiseasesChronic DiseaseDelivery of Health CareHumansMental HealthMultimorbidityPsychologyConceptsCardiovascular careCardiovascular diseaseHealth care systemRisk factorsBehavioural risk factor managementTraditional atherosclerotic risk factorsWagner's Chronic Care ModelCare systemAtherosclerotic risk factorsRisk factor managementChronic Care ModelCause of morbidityMental health burdenBehavioral risk factorsChronic cardiovascular diseaseHigh-intensity careAdverse health outcomesMental health disordersHealth psychologyEvidence-based approachComplex multimorbidityRisk patientsCardiovascular populationFactor managementChronic diseasesA Narrative Review of the Association Between Depression and Heart Disease Among Women: Prevalence, Mechanisms of Action, and Treatment
Rome D, Sales A, Leeds R, Usseglio J, Cornelius T, Monk C, Smolderen KG, Moise N. A Narrative Review of the Association Between Depression and Heart Disease Among Women: Prevalence, Mechanisms of Action, and Treatment. Current Atherosclerosis Reports 2022, 24: 709-720. PMID: 35751731, PMCID: PMC9398966, DOI: 10.1007/s11883-022-01048-0.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesCoronary DiseaseDepressionFemaleHumansMalePrevalenceRisk FactorsSex FactorsConceptsCoronary heart diseaseCardiovascular diseaseMechanism of actionHeart diseaseNarrative reviewManagement of depressionPrevalence of depressionRecent FindingsWomenCardiovascular outcomesAutonomic factorsDepression treatmentComorbid depressionTreatment inertiaGreater prevalenceTherapeutic targetPrevalenceStrong associationWomenDepressionDiseaseGreater mortalityTreatment effectsAssociationMenTreatment
2021
Relation of Cardiovascular Risk Factors to Mortality and Cardiovascular Events in Hospitalized Patients With Coronavirus Disease 2019 (from the Yale COVID-19 Cardiovascular Registry)
Pareek M, Singh A, Vadlamani L, Eder M, Pacor J, Park J, Ghazizadeh Z, Heard A, Cruz-Solbes AS, Nikooie R, Gier C, Ahmed ZV, Freeman JV, Meadows J, Smolderen KGE, Lampert R, Velazquez EJ, Ahmad T, Desai NR. Relation of Cardiovascular Risk Factors to Mortality and Cardiovascular Events in Hospitalized Patients With Coronavirus Disease 2019 (from the Yale COVID-19 Cardiovascular Registry). The American Journal Of Cardiology 2021, 146: 99-106. PMID: 33539857, PMCID: PMC7849530, DOI: 10.1016/j.amjcard.2021.01.029.Peer-Reviewed Original ResearchConceptsCardiovascular risk factorsCoronavirus disease 2019Risk factorsHigher troponin TCardiovascular diseaseCardiovascular eventsHospitalized patientsLaboratory findingsMental statusDisease 2019Multivariable binary logistic regression analysisTroponin TMajor adverse cardiovascular eventsPre-existing cardiovascular diseaseHigher C-reactive proteinCOVID-19 positive patientsPredictors of MACEPrevious ventricular arrhythmiaUse of P2YAdverse cardiovascular eventsProspective cohort studyTertiary care centerC-reactive proteinBinary logistic regression analysisPoor prognostic marker
2020
Association of Health Status Scores With Cardiovascular and Limb Outcomes in Patients With Symptomatic Peripheral Artery Disease: Insights From the EUCLID (Examining Use of Ticagrelor in Symptomatic Peripheral Artery Disease) Trial
Rymer JA, Mulder H, Smolderen KG, Hiatt WR, Conte MS, Berger JS, Norgren L, Mahaffey KW, Baumgartner I, Fowkes FG, Katona BG, Rockhold F, Jones WS, Patel MR. Association of Health Status Scores With Cardiovascular and Limb Outcomes in Patients With Symptomatic Peripheral Artery Disease: Insights From the EUCLID (Examining Use of Ticagrelor in Symptomatic Peripheral Artery Disease) Trial. Journal Of The American Heart Association 2020, 9: e016573. PMID: 32924754, PMCID: PMC7792388, DOI: 10.1161/jaha.120.016573.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesDouble-Blind MethodFemaleHealth Status IndicatorsHumansLower ExtremityMaleMiddle AgedOutcome Assessment, Health CarePeripheral Arterial DiseasePlatelet Aggregation InhibitorsQuality of LifeSurveys and QuestionnairesSymptom AssessmentTicagrelorVascular Surgical ProceduresVisual Analog ScaleConceptsMajor adverse cardiovascular eventsMajor adverse limb eventsAdverse cardiovascular eventsAdverse limb eventsLower extremity revascularizationPeripheral artery diseaseCardiovascular eventsHealth status instrumentsLimb eventsEUCLID trialVAS scoresArtery diseaseEQ-5DQuestionnaire scoresSubsequent major adverse cardiovascular eventsLow ankle-brachial indexSymptomatic peripheral artery diseaseLower extremity revascularization proceduresBaseline EQ-5DAnkle-brachial indexHealth status scoresEQ-5D scoresHealth status measurementHealth status changesSubsequent end points
2013
Cardiovascular Health
Rumsfeld JS, Alexander KP, Goff DC, Graham MM, Ho PM, Masoudi FA, Moser DK, Roger VL, Slaughter MS, Smolderen KG, Spertus JA, Sullivan MD, Treat-Jacobson D, Zerwic JJ. Cardiovascular Health. Circulation 2013, 127: 2233-2249. PMID: 23648778, DOI: 10.1161/cir.0b013e3182949a2e.Peer-Reviewed Original ResearchAmerican Heart AssociationCardiovascular DiseasesHealth StatusHealth SurveysHumansQuality of LifeUnited States
2010
Letter by Smolderen and Pelle Regarding Article, “Efficacy and Safety of Varenicline for Smoking Cessation in Patients With Cardiovascular Disease: A Randomized Trial”
Smolderen KG, Pelle AJ. Letter by Smolderen and Pelle Regarding Article, “Efficacy and Safety of Varenicline for Smoking Cessation in Patients With Cardiovascular Disease: A Randomized Trial”. Circulation 2010, 122: e445; author reply e446. PMID: 20805437, DOI: 10.1161/circulationaha.110.942086.Peer-Reviewed Original ResearchType D personality mediates the relationship between remembered parenting and perceived health.
van den Broek KC, Smolderen KG, Pedersen SS, Denollet J. Type D personality mediates the relationship between remembered parenting and perceived health. Journal Of The Academy Of Consultation-Liaison Psychiatry 2010, 51: 216-24. PMID: 20484719, DOI: 10.1176/appi.psy.51.3.216.Peer-Reviewed Original ResearchConceptsType D personalityD personalityHealth outcomesShort Form Health SurveyRemembered parentingGeneral Dutch populationBeck Depression InventoryAdverse childhood experiencesAdverse outcomesHospital AnxietyCardiovascular diseaseHealth SurveyDepression ScaleDepression InventoryDutch populationRemembered RelationshipOutcomesChildhood experiencesType DParent scaleAssociationHealth
2009
Preoperative Cardiac Risk Index Predicts Long-term Mortality and Health Status
Hoeks SE, Reimer W, van Gestel YR, Smolderen KG, Verhagen H, van Domburg RT, van Urk H, Poldermans D. Preoperative Cardiac Risk Index Predicts Long-term Mortality and Health Status. The American Journal Of Medicine 2009, 122: 559-565. PMID: 19376487, DOI: 10.1016/j.amjmed.2008.10.041.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiovascular DiseasesCerebrovascular DisordersConfidence IntervalsData CollectionDiabetes Mellitus, Type 1FemaleFollow-Up StudiesHealth StatusHealth SurveysHumansMaleMiddle AgedNetherlandsOdds RatioPerioperative CarePeripheral Vascular DiseasesPredictive Value of TestsPreoperative CarePrognosisRegression AnalysisRenal InsufficiencyRisk AdjustmentRisk AssessmentRisk FactorsSurveys and QuestionnairesSurvival AnalysisVascular Surgical ProceduresConceptsPeripheral Artery QuestionnaireImpaired health statusPeripheral arterial disease patientsArterial disease patientsInsulin-dependent diabetesLate mortalityPrognostic factorsHealth statusVascular surgeryRenal insufficiencyCerebrovascular diseaseDisease patientsDisease-specific Peripheral Artery QuestionnaireLong-term health statusPAQ summary scorePerioperative cardiac riskCardiac risk factorsCardiac Risk IndexLong-term mortalityPeripheral arterial diseaseImportant prognostic factorIndependent prognostic factorIschemic heart diseaseMultivariable regression analysisRisk index score