2022
Evidence-Based Clinical Practice Guidelines for Laser-Assisted Drug Delivery
Labadie JG, Ibrahim SA, Worley B, Kang BY, Rakita U, Rigali S, Arndt KA, Bernstein E, Brauer JA, Chandra S, Didwania A, DiGiorgio C, Donelan M, Dover JS, Galadari H, Geronemus RG, Goldman MP, Haedersdal M, Hruza G, Ibrahimi OA, Kauvar A, Kelly KM, Krakowski AC, Miest R, Orringer JS, Ozog DM, Ross EV, Shumaker PR, Sobanko JF, Suozzi K, Taylor MB, Teng JMC, Uebelhoer NS, Waibel J, Wanner M, Ratchev I, Christensen RE, Poon E, Miller CH, Alam M. Evidence-Based Clinical Practice Guidelines for Laser-Assisted Drug Delivery. JAMA Dermatology 2022, 158: 1193-1201. PMID: 35976634, DOI: 10.1001/jamadermatol.2022.3234.Peer-Reviewed Original ResearchConceptsLaser-assisted drug deliveryEvidence-based clinical practice guidelinesFractional laser-assisted drug deliveryClinical practice guidelinesPractice guidelinesSystematic reviewCutaneous squamous cell carcinomaCochrane Central RegisterExpert panelSquamous cell carcinomaDelphi consensus approachImpaired wound healingFitzpatrick skin typeEvidence-based guidanceAntibiotic prophylaxisAntifungal prophylaxisAntiviral prophylaxisDermal analgesiaCentral RegisterControlled TrialsActinic keratosisCell carcinomaActinic cheilitisMultidisciplinary panelInclusion criteriaFactors affecting outcomes of second intent healing of nasal defects after Mohs micrographic surgery
Kim DN, Kibbi N, Christensen SR, Leffell DJ, Suozzi KC. Factors affecting outcomes of second intent healing of nasal defects after Mohs micrographic surgery. Archives Of Dermatological Research 2022, 315: 67-73. PMID: 35112163, DOI: 10.1007/s00403-021-02306-y.Peer-Reviewed Original ResearchConceptsMohs micrographic surgeryMicrographic surgeryNasal defectsPost-operative followSingle surgical centerManchester Scar ScaleSignificant functional deficitsAverage defect sizeMMS stagesChart reviewNasal lesionsRetrospective studyFunctional deficitsSurgical centersNasal tumorsNasal siteRetrospective analysisScar outcomeBetter outcomesScar ScaleTumor typesMultivariate analysisDefect sizeTissue laxityNasal tip
2021
Clinical factors impacting clear margins of primary melanoma in situ with conventional excision in a retrospective cohort
Olamiju B, Suozzi KC, Leffell DJ, Christensen SR. Clinical factors impacting clear margins of primary melanoma in situ with conventional excision in a retrospective cohort. Journal Of The American Academy Of Dermatology 2021, 86: 966-967. PMID: 33848603, DOI: 10.1016/j.jaad.2021.03.114.Peer-Reviewed Original ResearchA Histopathologic Scoring System for Perineural Invasion Correlates With Adverse Outcomes in Patients With Cutaneous Squamous Cell Carcinoma.
Totonchy MB, McNiff JM, Suozzi KC, Leffell DJ, Christensen SR. A Histopathologic Scoring System for Perineural Invasion Correlates With Adverse Outcomes in Patients With Cutaneous Squamous Cell Carcinoma. Dermatologic Surgery 2021, 47: 445-451. PMID: 33795563, DOI: 10.1097/dss.0000000000002923.Peer-Reviewed Original ResearchConceptsCutaneous squamous cell carcinomaPerineural invasionSquamous cell carcinomaAdverse outcomesNerve diameterHistopathologic featuresPNI scoreCell carcinomaExtratumoral perineural invasionRetrospective cohort studyCurrent staging systemHistopathologic scoring systemTumor-related deathNumber of nervesLogistic regression analysisMedian followNerve involvementCohort studyLocal recurrenceSurgical excisionStaging systemRisk factorsMedian numberHistopathologic slidesNerve structures
2020
Predicting outcomes following second intent healing of periocular surgical defects
Kibbi N, Khan Y, Leffell DJ, Christensen SR, Suozzi KC. Predicting outcomes following second intent healing of periocular surgical defects. Archives Of Dermatological Research 2020, 313: 483-489. PMID: 32833078, DOI: 10.1007/s00403-020-02122-w.Peer-Reviewed Original ResearchConceptsMohs micrographic surgeryMedial canthusSingle academic surgical centerAcademic surgical centerConclusionsThis retrospective studyMedial canthal lesionAverage defect diameterMethodsRetrospective analysisTumor characteristicsPeriocular tumorsRetrospective studyPoor outcomePeriocular lesionsSurgical centersMicrographic surgeryWorse outcomesAnatomic locationAimThe purposeScar outcomeLarge lesionsUpper eyelidEyelid marginLid marginSurgical defectsLower eyelidCutaneous Photoprotection: A Review of the Current Status and Evolving Strategies.
Suozzi K, Turban J, Girardi M. Cutaneous Photoprotection: A Review of the Current Status and Evolving Strategies. The Yale Journal Of Biology And Medicine 2020, 93: 55-67. PMID: 32226337, PMCID: PMC7087054.Peer-Reviewed Original ResearchMeSH KeywordsEnvironmental ExposureHumansPhotobiologySkin NeoplasmsSun Protection FactorSunscreening AgentsUltraviolet RaysConceptsCutaneous squamous cell carcinomaBasal cell carcinomaCell carcinomaRisk factorsMajor environmental risk factorSquamous cell carcinomaAdditional risk factorsEnvironmental risk factorsDevelopment of melanomaUltraviolet radiation exposureLifestyle modificationTopical therapyImmune statusCutaneous carcinogenesisImmune factorsCell malignant transformationDrug Administration regulationsInsufficient evidenceMultifactorial mechanismsSkin cancerMalignant transformationFavorable aestheticsTumor developmentClonal expansionRadiation exposure