Skip to Main Content

INFORMATION FOR

    Jon Morrow, PhD, MD

    Raymond Yesner Professor of Pathology
    DownloadHi-Res Photo

    Are You a Patient?

    View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.

    View Doctor Profile

    Additional Titles

    Professor, MCD Biology

    About

    Titles

    Raymond Yesner Professor of Pathology

    Professor, MCD Biology

    Appointments

    Other Departments & Organizations

    Education & Training

    MD
    Yale University (1976)
    PhD
    Indiana University School of Medicine (1974)
    Resident
    Yale-New Haven Hospital
    Fellow
    Yale University School of Medicine

    Research

    Overview

    Our research focuses on understanding the structure and function of the spectrin-ankyrin-actin cytoskeleton and the mechanisms by which it mediates membrane receptor and adhesion-complex organization; signal transduction; and vesicle trafficking from the ER to the plasma membrane. Our recent studies implicate a major and unexpected role for the spectrin skeleton in the pathways of vesicle trafficking and membrane assembly. In parallel studies we are seeking to understand the molecular basis of diseases arising from aberrant cytoskeletal function. Studies are carried out both in vitro utilizing functional and biophysical assays; in cell culture using genetically modified systems; and in transgenic animals. Areas of special interest include organization of the plasma membrane in erythrocytes; vesicle trafficking and the establishment of polarity in epithelial cells; and the control of receptor organization at the synapse.

    Medical Research Interests

    Autopsy; Computer-Assisted Instruction; Medical Informatics; Pathology; Spectrin; Telepathology

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Jon Morrow's published research.

    Publications

    2024

    2022

    2003

    2002

    2001

    Clinical Care

    Overview

    Jon S. Morrow, MD, PhD, is the Raymond Yesner Professor of Pathology, Professor of Molecular and Cellular Biology, the chair of Pathology and the Chief of Pathology at Yale New Haven Hospital. He has led Pathology for nearly 30 years. An internationally recognized physician-scientist, Dr. Morrow’s research has pioneered studies on the structure, function and genetics of complex cell membrane scaffolds. These studies were among the first to reveal the molecular basis of several hereditary disorders of blood cells, diseases most commonly afflicting young children, as well as the molecular basis of movement disorders such as hereditary ataxia. This work is reported in over 200 original research publications and reviews.

    Under his leadership, the Pathology Department has grown to one of the nation’s foremost pathology programs, offering subspecialized expertise in all major areas of practice. Dr. Morrow personally co-authored the development of the first comprehensive anatomic pathology information system (CoPath®), now the most widely used anatomic lab information system across the Country. Building on that early initiative, the department was among the first to establish a dedicated informatics and computational pathology unit, and now leads the country in its information systems, which ensure optimal patient safety and laboratory efficiency. Other firsts for the Department under Dr. Morrow’s leadership include the introduction to Connecticut of computer-assisted cytologic screening and the incorporation of genetic sequencing technology, which is used for cancer diagnosis and tissue evaluation. Recent innovations include the development of new technologies that allow the identification of cancer patients who will optimally respond to emerging immunotherapies.

    Clinical Specialties

    Pathology; Anatomic Pathology; Hematopathology; Autopsy Pathology; Molecular & Genomic Pathology

    Board Certifications

    • Anatomic Pathology

      Certification Organization
      AB of Pathology
      Original Certification Date
      1980

    Yale Medicine News

    Get In Touch

    Contacts

    Academic Office Number
    Lab Number
    Office Fax Number
    Clinic Fax Number

    Locations

    • Patient Care Locations

      Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.