2020
Impact of cardiovascular comorbidities on inpatient mortality in patients hospitalized with neutropenic fever
Atallah-Yunes SA, Kadado AJ, Haddadin F, Sawalha K, Hernandez-Montfort J, Ali SS. Impact of cardiovascular comorbidities on inpatient mortality in patients hospitalized with neutropenic fever. Supportive Care In Cancer 2020, 29: 509-513. PMID: 32409990, DOI: 10.1007/s00520-020-05518-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultCardiovascular DiseasesCohort StudiesComorbidityFebrile NeutropeniaFemaleHospital MortalityHospitalizationHumansInpatientsMaleRetrospective StudiesConceptsCongestive heart failureNeutropenic feverCardiovascular comorbiditiesHospital mortalityHeart failureInpatient mortalityAtrial fibrillationRisk factorsCardiovascular risk factorsHigher inpatient mortalityRetrospective cohort studyTransient ischemic attackPeripheral vascular diseaseCoronary artery diseaseICD-10-CM codesSet of patientsIschemic attackCardiovascular morbidityCause mortalityCohort studyArtery diseasePrimary outcomeRisk stratificationCerebrovascular diseaseNIS database
2019
Age associated non-linear regulation of redox homeostasis in the anucleate platelet: Implications for CVD risk patients
Jain K, Tyagi T, Patell K, Xie Y, Kadado AJ, Lee SH, Yarovinsky T, Du J, Hwang J, Martin KA, Testani J, Ionescu CN, Hwa J. Age associated non-linear regulation of redox homeostasis in the anucleate platelet: Implications for CVD risk patients. EBioMedicine 2019, 44: 28-40. PMID: 31130473, PMCID: PMC6604369, DOI: 10.1016/j.ebiom.2019.05.022.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PhysiologicalAge FactorsAgedAged, 80 and overAgingAnimalsAntioxidantsApoptosisBiomarkersBlood PlateletsCardiovascular DiseasesComorbidityDisease Models, AnimalFemaleHomeostasisHumansMaleMiceMiddle AgedOxidation-ReductionOxidative StressPlatelet ActivationPlatelet AdhesivenessReactive Oxygen SpeciesRisk AssessmentRisk FactorsConceptsRisk patientsMouse studiesPlatelet phenotypeMajor adverse cardiovascular eventsHigh cardiovascular risk patientsAdaptive increaseAdverse cardiovascular eventsCentral pathophysiological roleCVD risk patientsCardiovascular risk patientsAggressive antiplatelet therapyEffect of comorbidityAge group 40Young healthy subjectsAntiplatelet therapyCardiovascular eventsYear age cohortAdvanced ageCVD patientsGroup 40Healthy subjectsPathophysiological roleElderly populationCardiovascular pathologyPatients