2018
Neurocognitive correlates of treatment response in children with Tourette's Disorder
Chang SW, McGuire JF, Walkup JT, Woods DW, Scahill L, Wilhelm S, Peterson AL, Dziura J, Piacentini J. Neurocognitive correlates of treatment response in children with Tourette's Disorder. Psychiatry Research 2018, 261: 464-472. PMID: 29407718, PMCID: PMC5809184, DOI: 10.1016/j.psychres.2017.12.066.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderBehavior therapyNeurocognitive functioningCo-occurring attention-deficit hyperactivity disorderPerformance speedTourette's disorderBrief neurocognitive batteryDeficit hyperactivity disorderBehavior therapy groupSmall negative associationNeurocognitive predictorsNeurocognitive correlatesCognitive functioningNeurocognitive batteryHabit learningPositive treatment responseHyperactivity disorderMotor inhibitionGroup differencesNeurocognitive statusFunctioningGreater baselineMemoryYouthNegative association
2017
Moderators and predictors of response to behavior therapy for tics in Tourette syndrome
Sukhodolsky DG, Woods DW, Piacentini J, Wilhelm S, Peterson AL, Katsovich L, Dziura J, Walkup JT, Scahill L. Moderators and predictors of response to behavior therapy for tics in Tourette syndrome. Neurology 2017, 88: 1029-1036. PMID: 28202705, PMCID: PMC5384839, DOI: 10.1212/wnl.0000000000003710.Peer-Reviewed Original ResearchConceptsPredictors of responseChronic tic disorderTic reductionTic disordersPsychiatric disordersYale Global Tic Severity Scale-Total Tic ScoreTic severityTourette syndromeClinical Global Impressions-Improvement scoreCo-occurring psychiatric disordersAnxiety disordersSubgroup of patientsTotal tic scoreMain outcome measuresPredictors of outcomeBehavior therapyComprehensive Behavioral InterventionAttention-deficit/hyperactivity disorderPremonitory urge severityReduction of ticsCo-occurring attention-deficit/hyperactivity disorderGreater tic severityTIC characteristicsTic improvementClinical characteristics
2013
Detecting a clinically meaningful change in tic severity in Tourette syndrome: A comparison of three methods
Jeon S, Walkup JT, Woods DW, Peterson A, Piacentini J, Wilhelm S, Katsovich L, McGuire JF, Dziura J, Scahill L. Detecting a clinically meaningful change in tic severity in Tourette syndrome: A comparison of three methods. Contemporary Clinical Trials 2013, 36: 414-420. PMID: 24001701, PMCID: PMC3999642, DOI: 10.1016/j.cct.2013.08.012.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBehavior TherapyChildHumansMaleMiddle AgedSeverity of Illness IndexTicsTourette SyndromeTreatment OutcomeYoung AdultConceptsOdds ratioTourette syndromeYGTSS total tic scoreChronic tic disorderPositive treatment responsePositive responseTic scoreTic disordersTreatment responseTic severityTreatment assignmentBehavioral treatmentSignal detection analysisBehavioral interventionsSyndromeCGICategorical measuresTrialsMeaningful changeSeverityPercent reductionOptimal sensitivityDimensional measuresResponse
2012
Randomized Trial of Behavior Therapy for Adults With Tourette Syndrome
Wilhelm S, Peterson AL, Piacentini J, Woods DW, Deckersbach T, Sukhodolsky DG, Chang S, Liu H, Dziura J, Walkup JT, Scahill L. Randomized Trial of Behavior Therapy for Adults With Tourette Syndrome. JAMA Psychiatry 2012, 69: 795-803. PMID: 22868933, PMCID: PMC3772729, DOI: 10.1001/archgenpsychiatry.2011.1528.Peer-Reviewed Original ResearchConceptsClinical Global Impressions-Improvement scaleYale Global Tic Severity ScaleComprehensive Behavioral InterventionTic Severity ScaleTourette syndromeBehavior therapySeverity ScaleBehavioral interventionsOutpatient research clinicTotal tic scoreLeast moderate severityChronic tic disorderGreater mean decreaseMonthly booster sessionsAdult patientsSupportive treatmentModerate severityTic scoreTic disordersPositive respondersResearch clinicBooster sessionsMean decreasePosttreatment evaluationPatients
2010
Behavior Therapy for Children With Tourette Disorder: A Randomized Controlled Trial
Piacentini J, Woods DW, Scahill L, Wilhelm S, Peterson AL, Chang S, Ginsburg GS, Deckersbach T, Dziura J, Levi-Pearl S, Walkup JT. Behavior Therapy for Children With Tourette Disorder: A Randomized Controlled Trial. JAMA 2010, 303: 1929-1937. PMID: 20483969, PMCID: PMC2993317, DOI: 10.1001/jama.2010.607.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBehavior TherapyChildFemaleHumansMaleSeverity of Illness IndexTourette SyndromeTreatment OutcomeConceptsComprehensive Behavioral InterventionClinical Global Impressions-Improvement scaleYale Global Tic Severity ScaleChronic tic disorderTic Severity ScaleBehavioral interventionsSupportive therapyTic disordersSeverity ScaleTourette's disorderBehavior therapyFirst-line treatmentControlled TrialsSevere ticsAntipsychotic medicationNeurologic conditionsPrimary diagnosisTic severityTreatment sessionsControl groupTherapySymptom severityAdverse effectsTreatment gainsMore children