1983
The Prognostic Importance of Clinical and Histologic Features in Asymptomatic and Symptomatic Primary Biliary Cirrhosis
Roll J, Boyer J, Barry D, Klatskin G. The Prognostic Importance of Clinical and Histologic Features in Asymptomatic and Symptomatic Primary Biliary Cirrhosis. New England Journal Of Medicine 1983, 308: 1-7. PMID: 6847917, DOI: 10.1056/nejm198301063080101.Peer-Reviewed Original ResearchConceptsPrimary biliary cirrhosisBiliary cirrhosisPoor prognosisSymptomatic primary biliary cirrhosisOnset of diseaseAsymptomatic patientsAsymptomatic diseaseClinical featuresHistologic featuresHistologic stagePrediction of riskPrognostic importanceSerum bilirubinHepatic fibrosisHistologic findingsPortal areasProlonged survivalMultivariate analysisPatientsControl populationPrognosisWeight lossElevated levelsLife expectancySurvival data
1974
Hepatic Injury from Chronic Hypervitaminosis a Resulting in Portal Hypertension and Ascites
Russell R, Boyer J, Bagheri S, Hruban Z. Hepatic Injury from Chronic Hypervitaminosis a Resulting in Portal Hypertension and Ascites. New England Journal Of Medicine 1974, 291: 435-440. PMID: 4843409, DOI: 10.1056/nejm197408292910903.Peer-Reviewed Original ResearchMeSH KeywordsAscitesBasement MembraneBiopsy, NeedleChemical and Drug Induced Liver InjuryCollagenFemaleHepatic VeinsHistocytochemistryHumansHypertension, PortalLipid MetabolismLiverLiver CirculationLiver CirrhosisMaleMicroscopy, ElectronMicroscopy, FluorescenceMiddle AgedSclerosisTime FactorsVitamin AConceptsPortal hypertensionHepatic blood flowChronic hypervitaminosis ALiver biopsy materialLipid storage cellsChronic hypervitaminosisFocal congestionVein sclerosisHepatic injuryPerisinusoidal fibrosisHypervitaminosis AChronic ingestionHepatic functionClinical signsHistologic examinationBlood flowUnusual lesionFrozen sectionsIto cellsPerisinusoidal spaceCirrhosisHypertensionAscitesVitaminLike material