1983
The Prognostic Importance of Clinical and Histologic Features in Asymptomatic and Symptomatic Primary Biliary Cirrhosis
Roll J, Boyer J, Barry D, Klatskin G. The Prognostic Importance of Clinical and Histologic Features in Asymptomatic and Symptomatic Primary Biliary Cirrhosis. New England Journal Of Medicine 1983, 308: 1-7. PMID: 6847917, DOI: 10.1056/nejm198301063080101.Peer-Reviewed Original ResearchConceptsPrimary biliary cirrhosisBiliary cirrhosisPoor prognosisSymptomatic primary biliary cirrhosisOnset of diseaseAsymptomatic patientsAsymptomatic diseaseClinical featuresHistologic featuresHistologic stagePrediction of riskPrognostic importanceSerum bilirubinHepatic fibrosisHistologic findingsPortal areasProlonged survivalMultivariate analysisPatientsControl populationPrognosisWeight lossElevated levelsLife expectancySurvival data
1981
Prognostic indicators of hepatic injury following jejunoileal bypass performed for refractory obesity: A prospective study
Haines N, Baker A, Boyer J, Glagov S, Schneir H, Jaspan J, Ferguson D. Prognostic indicators of hepatic injury following jejunoileal bypass performed for refractory obesity: A prospective study. Hepatology 1981, 1: 161-167. PMID: 7286895, DOI: 10.1002/hep.1840010212.Peer-Reviewed Original ResearchConceptsJejunoileal bypassInactive cirrhosisWeight lossHepatic injuryLiver biopsyPericentral fibrosisClinical liver failureOral nutritional supplementationAlcoholic liver diseaseSerum aspartate aminotransferaseGreater weight lossRapid weight lossCryptogenic cirrhosisRefractory obesityAsymptomatic patientsOlder patientsLiver failureLiver injuryLiver diseaseParenteral alimentationFatty infiltrationHistologic evidenceProspective studyPrognostic indicatorClinical evaluation