2003
82 The cholesterol-7α hydroxylase promoter factor (CPF) up-regulates the human multidrug resistance-associated protein 3 (MRP3) and is induced by bile salts in HEPG2 cells
Chen W, Denson L, Bohan A, Cai S, Wang L, Soroka C, Boyer J. 82 The cholesterol-7α hydroxylase promoter factor (CPF) up-regulates the human multidrug resistance-associated protein 3 (MRP3) and is induced by bile salts in HEPG2 cells. Hepatology 2003, 38: 195. DOI: 10.1016/s0270-9139(03)80125-8.Peer-Reviewed Original Research
2001
Cellular localization and up‐regulation of multidrug resistance–associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver
Soroka C, Lee J, Azzaroli F, Boyer J. Cellular localization and up‐regulation of multidrug resistance–associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver. Hepatology 2001, 33: 783-791. PMID: 11283840, DOI: 10.1053/jhep.2001.23501.Peer-Reviewed Original ResearchConceptsObstructive cholestasisMultidrug resistance-associated protein 3Bile duct-ligated animalsMultidrug resistanceToxic bile acidsModel of cholestasisDuct-ligated animalsExpression of MRP3Intensity of stainingHepatocytes of liverWestern blot analysisBile ductHepatic expressionCentral veinCholestasisMRP3 expressionNormal liverBile acidsPericentral regionsIndirect immunofluorescenceProtein 3Days postligationMRP3Mrp2 proteinLiver