1994
Expression and characterization of a functional rat liver Na+ bile acid cotransport system in COS-7 cells
Boyer J, Ng O, Ananthanarayanan M, Hofmann A, Schteingart C, Hagenbuch B, Stieger B, Meier P. Expression and characterization of a functional rat liver Na+ bile acid cotransport system in COS-7 cells. American Journal Of Physiology 1994, 266: g382-g387. PMID: 8166278, DOI: 10.1152/ajpgi.1994.266.3.g382.Peer-Reviewed Original ResearchConceptsCOS-7 cellsCotransport systemBile acid transporterUrsodeoxycholic acidTaurochenodeoxycholic acidAcid cotransport systemTauroursodeoxycholic acidBile acidsRat hepatocytesAbsence of sodiumChenodeoxycholic acidCOS cellsEmpty plasmidPMAMneo vectorCholic acidBile acid cotransporterMicroM bilirubinRat liverEvidence of expressionCell linesAcid transportersPosttranslational factorsProgressive uptakeCotransporterAcid cotransporter
1993
Phylogenic and ontogenic expression of hepatocellular bile acid transport.
Boyer J, Hagenbuch B, Ananthanarayanan M, Suchy F, Stieger B, Meier P. Phylogenic and ontogenic expression of hepatocellular bile acid transport. Proceedings Of The National Academy Of Sciences Of The United States Of America 1993, 90: 435-438. PMID: 8421672, PMCID: PMC45677, DOI: 10.1073/pnas.90.2.435.Peer-Reviewed Original ResearchConceptsAcid transportMammalian speciesFull-length cDNA probeDependent bile acid transportMammalian fetal developmentAcid cotransport systemVertebrate evolutionBile acid transportOntogenic expressionLower vertebratesNonmammalian speciesPrior functional studiesHepatoma cell lineNorthern analysisAcid transportersDedifferentiated hepatocytesCDNA probeTransport systemAcid cotransporterFunctional studiesXenopus oocytesSmall skateSpeciesMRNACell lines