Efficiency of immunohistochemical p16 expression and HPV typing in cervical squamous intraepithelial lesion grading and review of the p16 literature
Yıldız I, Usubütün A, Fırat P, Ayhan A, Küçükali T. Efficiency of immunohistochemical p16 expression and HPV typing in cervical squamous intraepithelial lesion grading and review of the p16 literature. Pathology - Research And Practice 2007, 203: 445-449. PMID: 17543474, DOI: 10.1016/j.prp.2007.03.010.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkers, TumorCervix UteriCyclin-Dependent Kinase Inhibitor p16FemaleHumansImmunohistochemistryNeoplasms, Squamous CellPapillomaviridaePapillomavirus InfectionsPredictive Value of TestsReproducibility of ResultsSensitivity and SpecificitySeverity of Illness IndexUterine Cervical DysplasiaUterine Cervical NeoplasmsConceptsLSIL casesHSIL casesCervical epithelial dysplasiaFull-thickness stainingHR-HPV positivityImmunohistochemical p16 expressionCervical cancer precursorsHPV-positive casesHR-HPV typesFull thicknessExpression of p16LSIL groupRare stainingHR-HPVHPV infectionP16 positivityHPV typesHPV typingLesion gradingCancer precursorsCervix epitheliumEpithelial dysplasiaImmunohistochemical panelInfection positivityPositivity rate