Featured Publications
Cat Scratch Disease: 9 Years of Experience at a Pediatric Center
Amin O, Rostad CA, Gonzalez M, Rostad BS, Caltharp S, Quincer E, Betke BA, Gottdenker NL, Wilson JJ, Shane AL, Elmontser M, Camacho-Gonzalez A, Senior T, Smith O, Anderson EJ, Yildirim I. Cat Scratch Disease: 9 Years of Experience at a Pediatric Center. Open Forum Infectious Diseases 2022, 9: ofac426. PMID: 36072697, PMCID: PMC9439574, DOI: 10.1093/ofid/ofac426.Peer-Reviewed Original ResearchCat-scratch diseaseClinical featuresAtypical clinical manifestationsPediatric hospital systemMajority of casesPediatric centersAtypical presentationCanine exposureCat exposureMedian ageRegional lymphadenopathyClinical manifestationsHepatic microabscessesPhysical examinationScratch diseaseMedical recordsPolymerase chain reactionRisk factorsSchool-aged childrenRetrospective analysisCytopathological resultsPatient careLymphadenopathyRadiographic imagingHospital system
2019
Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Infections in Young Infants: A Latent Class Analysis.
Lalani K, Yildirim I, Phadke VK, Bednarczyk RA, Omer SB. Assessment and Validation of Syndromic Case Definitions for Respiratory Syncytial Virus Infections in Young Infants: A Latent Class Analysis. The Pediatric Infectious Disease Journal 2019, 38: 1177-1182. PMID: 31568250, DOI: 10.1097/inf.0000000000002468.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusSyndromic case definitionsCase definitionYoung infantsWorld Health OrganizationRSV infectionLatent class analysisPredictive valueLaboratory-confirmed RSV infectionRespiratory syncytial virus infectionSyncytial virus infectionAcute respiratory infectionsHigh positive predictive valueRoutine clinical careStandardized case definitionsHigh-resource settingsAppropriate case definitionsHigh-income settingsNegative predictive valueMonths of agePositive predictive valueRespiratory infectionsVaccine evaluationClinical featuresPediatric morbidityIncidence of invasive Haemophilus influenzae infections in children with sickle cell disease
Yee ME, Bakshi N, Graciaa SH, Lane PA, Jerris RC, Wang YF, Yildirim I. Incidence of invasive Haemophilus influenzae infections in children with sickle cell disease. Pediatric Blood & Cancer 2019, 66: e27642. PMID: 30724001, PMCID: PMC6472970, DOI: 10.1002/pbc.27642.Peer-Reviewed Original ResearchConceptsSickle cell diseaseComprehensive clinical databaseInfluenzae infectionAntibiotic prophylaxisInfluenzae diseaseInvasive infectionsCell diseaseInvasive Haemophilus influenzae infectionsPediatric tertiary care centerHaemophilus influenzae type bLarge pediatric tertiary care centerUniversal antibiotic prophylaxisSterile body fluid culturesTertiary care centerHaemophilus influenzae infectionsBody fluid culturesInfluenzae type bYears of ageDistribution of serotypesNonvaccine serotypesClinical featuresOverall incidenceCare centerFluid cultureIncidence rate
2018
2354. Performance of Novel Clinical Case Definitions for Respiratory Syncytial Virus Infections in Young Infants: A Latent Class Analysis
Lalani K, Yildirim I, Phadke V, Bednarczyk R, Omer S. 2354. Performance of Novel Clinical Case Definitions for Respiratory Syncytial Virus Infections in Young Infants: A Latent Class Analysis. Open Forum Infectious Diseases 2018, 5: s700-s701. PMCID: PMC6255342, DOI: 10.1093/ofid/ofy210.2007.Peer-Reviewed Original ResearchRespiratory syncytial virusLaboratory-confirmed RSV infectionAcute respiratory infectionsCase definitionNegative predictive valueWorld Health OrganizationRSV infectionNovel RSV therapeuticsRoutine clinical careLatent class analysisHigh-resource settingsAppropriate case definitionsMonths of ageRSV therapeuticsRespiratory infectionsClinical featuresPediatric morbiditySyncytial virusDisease burdenClinical careChild healthcarePredictive valueYoung infantsMajor causeHealth Organization