1979
Influence of Aminophylline and Cyclic AMP on Glycogen Metabolism in Fetal Rat Lung in Organ Culture
Maniscalco W, Wilson C, Gross I. Influence of Aminophylline and Cyclic AMP on Glycogen Metabolism in Fetal Rat Lung in Organ Culture. Pediatric Research 1979, 13: 1319-1322. PMID: 230447, DOI: 10.1203/00006450-197912000-00003.Peer-Reviewed Original ResearchConceptsFetal rat lungRat lungCyclic AMPFetal pulmonary surfactantInfluence of aminophyllineEffect of aminophyllineGlycogen synthase I activityOrgan cultureLung phospholipid synthesisGlycogen metabolismTotal phosphorylase activityDibutyryl cyclic AMPMonophosphate phosphodiesterase inhibitorSynthase I activityPhospholipid synthesisAminophyllinePhosphodiesterase inhibitorGlycogen contentLungGlycogen breakdownCyclic AMP treatmentAMP treatmentPulmonary surfactantAMPPhosphorylase activity
1978
Development of glycogen and phospholipid metabolism in fetal and newborn rat lung
Maniscalco W, Wilson C, Gross I, Gobran L, Rooney S, Warshaw J. Development of glycogen and phospholipid metabolism in fetal and newborn rat lung. Biochimica Et Biophysica Acta 1978, 530: 333-346. PMID: 100141, DOI: 10.1016/0005-2760(78)90153-4.Peer-Reviewed Original ResearchConceptsNewborn rat lungGlycogen phosphorylase activityFetal lungRat lungGlycogen concentrationFetal lung glycogenFirst postnatal dayPhosphorylase activityTotal glycogen synthaseTotal glycogen phosphorylase activityMajor metabolic substratesLung glycogenPhosphatidylcholine synthesisGlycogen synthase activityIncorporation of cholinePostnatal dayGlycogen depletionDay 19LungGestationDay 20Adult lungMammalian fetusGlycogen contentTotal phospholipids