1979
Influence of Aminophylline and Cyclic AMP on Glycogen Metabolism in Fetal Rat Lung in Organ Culture
Maniscalco W, Wilson C, Gross I. Influence of Aminophylline and Cyclic AMP on Glycogen Metabolism in Fetal Rat Lung in Organ Culture. Pediatric Research 1979, 13: 1319-1322. PMID: 230447, DOI: 10.1203/00006450-197912000-00003.Peer-Reviewed Original ResearchConceptsFetal rat lungRat lungCyclic AMPFetal pulmonary surfactantInfluence of aminophyllineEffect of aminophyllineGlycogen synthase I activityOrgan cultureLung phospholipid synthesisGlycogen metabolismTotal phosphorylase activityDibutyryl cyclic AMPMonophosphate phosphodiesterase inhibitorSynthase I activityPhospholipid synthesisAminophyllinePhosphodiesterase inhibitorGlycogen contentLungGlycogen breakdownCyclic AMP treatmentAMP treatmentPulmonary surfactantAMPPhosphorylase activity
1977
AMINOPHYLLINE STIMULATES PHOSPHOLIPID SYNTHESIS BY FETAL RAT LUNG IN ORGAN CULTURE
Gross I, Rooney S, Warshaw J. AMINOPHYLLINE STIMULATES PHOSPHOLIPID SYNTHESIS BY FETAL RAT LUNG IN ORGAN CULTURE. Pediatric Research 1977, 11: 571-571. DOI: 10.1203/00006450-197704000-01210.Peer-Reviewed Original ResearchFetal rat lungRat lungInfluence of aminophyllineAdministration of aminophyllineOrgan cultureLung phospholipid synthesisCyclic AMPAminophylline effectsDays lungsDibutyryl cyclic AMPNonspecific stimulationLES stimulationIncorporation of cholineMM aminophyllineFetal rabbitsPhospholipid synthesisAminophyllineProtein/hourLungDay fetusesSignificant increaseF12 mediumSph synthesisStimulationExposure
1976
The influence of postnatal nutritional deprivation on the phospholipid content of developing rat lung
Gross I, Ilic I, Wilson C, Rooney S. The influence of postnatal nutritional deprivation on the phospholipid content of developing rat lung. Biochimica Et Biophysica Acta 1976, 441: 412-422. PMID: 9987, DOI: 10.1016/0005-2760(76)90238-1.Peer-Reviewed Original ResearchConceptsLung cell numberLung lavage phospholipidPostnatal nutritional deprivationTotal phospholipidsStandard rat chowLung protein contentPhosphatidylcholine contentRole of nutritionLung phospholipid synthesisFat-fed animalsLung surfactant productionLavage phospholipidsGlucose-fed groupRat chowLung lavageLung tissueDietary regimensMicrosomal fatty acid elongationRat lungLung proteinFasted animalsProtein dietLungNutritional deprivationAcetyl-CoA carboxylase