Prior antiplatelet therapy and haematoma expansion after primary intracerebral haemorrhage: an individual patient-level analysis of CLEAR III, MISTIE III and VISTA-ICH
Murthy S, Roh DJ, Chatterjee A, McBee N, Parikh NS, Merkler AE, Navi BB, Falcone GJ, Sheth KN, Awad I, Hanley D, Kamel H, Ziai WC. Prior antiplatelet therapy and haematoma expansion after primary intracerebral haemorrhage: an individual patient-level analysis of CLEAR III, MISTIE III and VISTA-ICH. Journal Of Neurology Neurosurgery & Psychiatry 2020, 92: 364-369. PMID: 33106367, PMCID: PMC8071838, DOI: 10.1136/jnnp-2020-323458.Peer-Reviewed Original ResearchPrior antiplatelet therapyAntiplatelet therapyLobar intracerebral hemorrhageIntracerebral hemorrhagePrimary intracerebral hemorrhageHaematoma expansionHaematoma volumeHaematoma locationCause mortalityIII trialsStudy cohortMajor disabilitySecondary analysisIndividual patient-level analysisPhase III trialsLarge heterogeneous cohortIndividual patient dataPatient-level analysisMISTIE IIISecondary outcomesDeep hemorrhagesPrimary outcomeICH locationMRS distributionFunctional outcome