2014
Serum B‐type natriuretic peptide in the initial workup of patients with new onset ascites: A diagnostic accuracy study
Farias AQ, Silvestre OM, Garcia‐Tsao G, da Costa Seguro L, de Campos Mazo D, Bacal F, Andrade JL, Gonçalves LL, Strunz C, Ramos DS, Polli D, Pugliese V, Rodrigues AC, Furtado MS, Carrilho FJ, D'Albuquerque LA. Serum B‐type natriuretic peptide in the initial workup of patients with new onset ascites: A diagnostic accuracy study. Hepatology 2014, 59: 1043-1051. PMID: 23907731, DOI: 10.1002/hep.26643.Peer-Reviewed Original ResearchConceptsSerum B-type natriuretic peptideB-type natriuretic peptideSerum-ascites albumin gradientNew-onset ascitesDiagnosis of HFHeart failureCause of ascitesConsecutive patientsNatriuretic peptideTotal protein concentrationResult of HFHighest positive likelihood ratioLow negative likelihood ratioWorkup of patientsCross-sectional studyPg/mLPositive likelihood ratioDiagnostic accuracy studiesNegative likelihood ratioDiagnostic paracentesisPeritoneal diseaseInitial workupLikelihood ratioConstrictive pericarditisValidation cohort
2013
Serum B-type natriuretic peptide is more accurate than ascites analyses in the diagnosis of ascites related to heart failure
Farias A, Silvestre O, Bacal F, Garcia-Tsao G, Seguro L, Mazo D, Andrade J, Furtado M, Carrilho F, D'Albuquerque L. Serum B-type natriuretic peptide is more accurate than ascites analyses in the diagnosis of ascites related to heart failure. European Heart Journal 2013, 34: p4241. DOI: 10.1093/eurheartj/eht309.p4241.Peer-Reviewed Original ResearchSerum B-type natriuretic peptideB-type natriuretic peptideSerum-ascites albumin gradientDiagnosis of HFNew-onset ascitesHeart failureConsecutive patientsNatriuretic peptideAscites analysisAscitic fluidTotal protein concentrationHighest positive likelihood ratioCause of ascitesLow negative likelihood ratioWorkup of patientsCross-sectional studyDiagnosis of ascitesPg/mLPositive likelihood ratioNegative likelihood ratioDiagnostic paracentesisLikelihood ratioPeritoneal diseaseConstrictive pericarditisValidation cohort
2012
Spontaneous bacterial peritonitis
Garcia‐Tsao G. Spontaneous bacterial peritonitis. 2012, 745-750. DOI: 10.1002/9781118321386.ch100.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSpontaneous bacterial peritonitisBacterial peritonitisPoor liver synthetic functionShort-term antibiotic prophylaxisCompatible clinical pictureHospitalized cirrhotic patientsLiver synthetic functionPolymorphonuclear cell countAntibiotic prophylaxisDiagnostic paracentesisIntravenous antibioticsOral norfloxacinSecondary prophylaxisGastrointestinal bleedGastrointestinal hemorrhageLiver transplantationRenal dysfunctionAlbumin therapyCirrhotic patientsAcute infectionImportant complicationClinical pictureCommon infectionsActive infectionPatientsParacentesis
De Gottardi A, Yeo C, Garcia‐Tsao G. Paracentesis. 2012, 1158-1162. DOI: 10.1002/9781118321386.ch154.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsDiagnostic paracentesisTherapeutic paracentesisAscitic fluidNew-onset ascitesAdministration of albuminSpontaneous bacterial peritonitisSite of paracentesisFormal contraindicationBowel perforationAbdominal ultrasoundBacterial peritonitisMajor complicationsSpecific etiologyAbdominal cavityParacentesisAscitesCell countBlood culture bottlesPatient consentSingle procedureFrequent technical problemsLeakage of fluidTherapeutic purposesPatientsMedical proceduresAscites
Garcia‐Tsao G. Ascites. 2012, 103-106. DOI: 10.1002/9781118321386.ch17.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsRight heart failurePeritoneal malignancyHeart failureHepatic sinusoidal pressureLow-protein ascitesNew-onset ascitesSpontaneous bacterial peritonitisEtiology of ascitesRoutine laboratory testsRisk of infectionAccumulation of fluidDiagnostic paracentesisBacterial peritonitisCareful historyPhysical examinationCirrhotic ascitesLiver architecturePeritoneal cavityHepatic sinusoidsAscitesPeritoneal lymphaticsCell countCirrhosisProtein levelsSinusoidal pressure
2011
Ascites
Garcia‐Tsao G. Ascites. 2011, 210-233. DOI: 10.1002/9781444341294.ch10.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsHepatorenal syndromeBacterial infectionsBaseline renal dysfunctionPeripheral arterial vasodilatationAcute kidney injurySecond-line treatmentMainstay of treatmentSpontaneous bacterial peritonitisSympathetic nervous systemEffective blood volumeSpontaneous bacterial infectionsCommon bacterial infectionsSigns of infectionLong-term safetyDiagnostic paracentesisIntravenous albuminPrerenal typeSinusoidal hypertensionAldosterone systemArterial vasodilatationKidney injuryLiver transplantationRefractory ascitesRenal dysfunctionSodium restriction
1992
SPONTANEOUS BACTERIAL PERITONITIS
Garcia-Tsao G. SPONTANEOUS BACTERIAL PERITONITIS. Gastroenterology Clinics Of North America 1992, 21: 257-275. PMID: 1568776, DOI: 10.1016/s0889-8553(21)00617-8.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsLiver diseaseLow ascitic fluid protein concentrationIntravenous broad-spectrum antibioticsAscitic fluid protein concentrationEpisode of SBPInfection of ascitesAdvanced liver diseaseThird of patientsBroad-spectrum antibioticsLong-term survivalFluid protein concentrationHepatic reticuloendothelial systemDiagnostic paracentesisSPONTANEOUS BACTERIALAbdominal painProphylactic antibioticsAcute episodeCirrhotic patientsGram-negative enteric bacteriaPeripheral destructionPMN countCompatible symptomsEarly therapyCirrhotic ascitesInfectious source