2021
Significant Liver Injury During Hospitalization for COVID-19 Is Not Associated With Liver Insufficiency or Death
Chew M, Tang Z, Radcliffe C, Caruana D, Doilicho N, Ciarleglio MM, Deng Y, Garcia-Tsao G. Significant Liver Injury During Hospitalization for COVID-19 Is Not Associated With Liver Insufficiency or Death. Clinical Gastroenterology And Hepatology 2021, 19: 2182-2191.e7. PMID: 34004326, PMCID: PMC8123528, DOI: 10.1016/j.cgh.2021.05.022.Peer-Reviewed Original ResearchConceptsSignificant liver injuryLiver injuryLiver insufficiencyCOVID-19High-sensitivity C-reactive protein valuesC-reactive protein valuesDrug-induced liver injuryHepatocellular liver injuryInternational normalized ratioMultivariate logistic regressionHyperinflammatory stateTocilizumab useVasopressor useConcomitant medicationsConsecutive patientsIndependent predictorsLiver failureBilirubin levelsD-dimerTest abnormalitiesNormalized ratioAlanine aminotransferaseHospitalizationPatientsInjury
2014
Serum B‐type natriuretic peptide in the initial workup of patients with new onset ascites: A diagnostic accuracy study
Farias AQ, Silvestre OM, Garcia‐Tsao G, da Costa Seguro L, de Campos Mazo D, Bacal F, Andrade JL, Gonçalves LL, Strunz C, Ramos DS, Polli D, Pugliese V, Rodrigues AC, Furtado MS, Carrilho FJ, D'Albuquerque LA. Serum B‐type natriuretic peptide in the initial workup of patients with new onset ascites: A diagnostic accuracy study. Hepatology 2014, 59: 1043-1051. PMID: 23907731, DOI: 10.1002/hep.26643.Peer-Reviewed Original ResearchConceptsSerum B-type natriuretic peptideB-type natriuretic peptideSerum-ascites albumin gradientNew-onset ascitesDiagnosis of HFHeart failureCause of ascitesConsecutive patientsNatriuretic peptideTotal protein concentrationResult of HFHighest positive likelihood ratioLow negative likelihood ratioWorkup of patientsCross-sectional studyPg/mLPositive likelihood ratioDiagnostic accuracy studiesNegative likelihood ratioDiagnostic paracentesisPeritoneal diseaseInitial workupLikelihood ratioConstrictive pericarditisValidation cohort
2013
Serum B-type natriuretic peptide is more accurate than ascites analyses in the diagnosis of ascites related to heart failure
Farias A, Silvestre O, Bacal F, Garcia-Tsao G, Seguro L, Mazo D, Andrade J, Furtado M, Carrilho F, D'Albuquerque L. Serum B-type natriuretic peptide is more accurate than ascites analyses in the diagnosis of ascites related to heart failure. European Heart Journal 2013, 34: p4241. DOI: 10.1093/eurheartj/eht309.p4241.Peer-Reviewed Original ResearchSerum B-type natriuretic peptideB-type natriuretic peptideSerum-ascites albumin gradientDiagnosis of HFNew-onset ascitesHeart failureConsecutive patientsNatriuretic peptideAscites analysisAscitic fluidTotal protein concentrationHighest positive likelihood ratioCause of ascitesLow negative likelihood ratioWorkup of patientsCross-sectional studyDiagnosis of ascitesPg/mLPositive likelihood ratioNegative likelihood ratioDiagnostic paracentesisLikelihood ratioPeritoneal diseaseConstrictive pericarditisValidation cohort
2009
Use of Over-the-Counter Analgesics Is Not Associated With Acute Decompensation in Patients With Cirrhosis
Khalid SK, Lane J, Navarro V, Garcia–Tsao G. Use of Over-the-Counter Analgesics Is Not Associated With Acute Decompensation in Patients With Cirrhosis. Clinical Gastroenterology And Hepatology 2009, 7: 994-999. PMID: 19394441, PMCID: PMC3777825, DOI: 10.1016/j.cgh.2009.04.015.Peer-Reviewed Original ResearchMeSH KeywordsAcetaminophenAdultAgedAged, 80 and overAlcohol DrinkingAnalgesics, Non-NarcoticAnti-Inflammatory Agents, Non-SteroidalCase-Control StudiesContraindicationsFemaleHospitalizationHumansLiverLiver CirrhosisMaleMiddle AgedNonprescription DrugsPainProspective StudiesSurveys and QuestionnairesYoung AdultConceptsNonsteroidal anti-inflammatory drugsAcute hepatic decompensationAnti-inflammatory drugsCirrhotic patientsAlcohol ingestionCounter analgesicsHepatic decompensationAlcoholic cirrhosisNonsteroidal anti-inflammatory drug useAnti-inflammatory drug useDecompensation of cirrhosisConsecutive cirrhotic patientsTertiary care hospitalEffect of analgesicsCase-control studyRecent alcohol ingestionRecent alcohol useAcetaminophen useLiver clinicNoncirrhotic controlsNoncirrhotic patientsAcute decompensationFurther decompensationCare hospitalConsecutive patients
1985
The diagnosis of bacterial peritonitis: Comparison of pH, lactate concentration and leukocyte count
Garcia‐Tsao G, Conn H, Lerner E. The diagnosis of bacterial peritonitis: Comparison of pH, lactate concentration and leukocyte count. Hepatology 1985, 5: 91-96. PMID: 3967868, DOI: 10.1002/hep.1840050119.Peer-Reviewed Original ResearchConceptsPolymorphonuclear cell countAscitic fluid lactateBacterial peritonitisAscitic fluidPeritoneal metastasisAscitic fluid polymorphonuclear cell countLactate gradientLactate concentrationAscitic fluid glucoseDiagnostic cutoff levelUninfected ascitesCirrhotic patientsLiver involvementTuberculous peritonitisConsecutive patientsPMN countArterial lactateLeukocyte countArterial bloodCutoff levelCell countFluid glucosePeritonitisPatientsDiagnostic accuracy