2023
Characterization of childhood trauma, hippocampal mediation and Cannabis use in a large dataset of psychosis and non-psychosis individuals
Del Re E, Yassin W, Zeng V, Keedy S, Alliey-Rodriguez N, Ivleva E, Hill S, Rychagov N, McDowell J, Bishop J, Mesholam-Gately R, Merola G, Lizano P, Gershon E, Pearlson G, Sweeney J, Clementz B, Tamminga C, Keshavan M. Characterization of childhood trauma, hippocampal mediation and Cannabis use in a large dataset of psychosis and non-psychosis individuals. Schizophrenia Research 2023, 255: 102-109. PMID: 36989667, DOI: 10.1016/j.schres.2023.03.029.Peer-Reviewed Original ResearchConceptsChildhood Trauma QuestionnaireChildhood traumaPsychosis onsetBipolar disorder type 1Rich brain regionsAbuse/dependenceHigh childhood traumaSevere childhood traumaPolygenic risk scoresRisk scoreClinical interviewersSchizoaffective disorderMulticenter sampleSurvival analysisCA exposureYounger ageBrain regionsType 1Psychosis riskLower ageCeiling effectsHippocampusTrauma QuestionnaireSZ-polygenic risk scoreGenetic risk
2021
Anterior-posterior axis of hippocampal subfields across psychoses: A B-SNIP study
del Re E, Zeng V, Alliey-Rodriguez N, Lizano P, Bolo N, Lutz O, Pearlson G, Sweeney J, Clementz B, Gershon E, Tamminga C, Keshavan M. Anterior-posterior axis of hippocampal subfields across psychoses: A B-SNIP study. Biomarkers In Neuropsychiatry 2021, 5: 100037. DOI: 10.1016/j.bionps.2021.100037.Peer-Reviewed Original ResearchVolumetric abnormalitiesPsychosis probandsBipolar type 1Granule cell layerT MRI scansB-SNIP studyB-SNIPDentate gyrusBipolar-Schizophrenia NetworkHealthy controlsClinical dataHippocampal subfieldsDSM categoriesMRI scansSchizoaffective disorderHippocampusType 1Schizophrenia NetworkAbnormalitiesUnaffected relativesAnterior-posterior axisSchizophreniaPsychosisProbandsConclusions Differences
1994
Depression Induced Cognitive Impairment
Rabins P, Pearlson G. Depression Induced Cognitive Impairment. 1994, 667-679. DOI: 10.1007/978-1-4615-6805-6_41.Peer-Reviewed Original ResearchAffective disordersCognitive impairmentAffective syndromeOrganic affective syndromeInduced Cognitive ImpairmentCognitive-affective disordersPoor cognitive performanceTerm pseudodementiaDementia syndromesClinical stateDelirious maniaSet of symptomsCognitive symptomsCognitive disordersAffective symptomsType 2Type 1SyndromeSymptomsDisordersCognitive performanceDepressionPseudodementiaImpairmentPrimary condition