1990
Demonstration of naturalistic methods for cocaine smoking by human volunteers
Foltin R, Fischman M, Nestadt G, Stromberger H, Cornell E, Pearlson G. Demonstration of naturalistic methods for cocaine smoking by human volunteers. Drug And Alcohol Dependence 1990, 26: 145-154. PMID: 2242715, DOI: 10.1016/0376-8716(90)90121-t.Peer-Reviewed Original ResearchConceptsVenous blood levelsClinical research unitBlood level curvesFirst doseSubsequent dosesBlood pressureDosing sessionsBlood levelsAcute toleranceCocaine smokingHeart rateDose sessionAscending limbBaseline levelsCardiovascular activityHuman volunteersSubjective effectsTransient increaseResearch volunteersDosesMale research volunteersCocaineVolunteersSubjectsLimb
1988
Late-Onset Schizophrenia Studying Clinical Validity
V.Jeste D, Harris M, Pearlson G, Rabins P, Lesser I, Miller B, Coles C, Yassa R. Late-Onset Schizophrenia Studying Clinical Validity. Psychiatric Clinics Of North America 1988, 11: 1-13. PMID: 3380754, DOI: 10.1016/s0193-953x(18)30513-6.Peer-Reviewed Original ResearchConceptsLate-onset schizophreniaSchizophrenic patientsYoung schizophrenic patientsClinical characteristicsChronic courseAge 45Onset schizophreniaParanoid typeClinical validityAuditory hallucinationsLow dosesBizarre delusionsSchizophreniaPatientsRelevant literatureNeurolepticsIllnessDosesHallucinations
1982
Intracortical kainic acid induces an assymmetrical behavioral response in the rat
Kubos K, Pearlson G, Robinson R. Intracortical kainic acid induces an assymmetrical behavioral response in the rat. Brain Research 1982, 239: 303-309. PMID: 7093686, DOI: 10.1016/0006-8993(82)90857-5.Peer-Reviewed Original ResearchConceptsKainic acidCortical noradrenergic terminalsDay postoperative periodRight frontal cortexNoradrenergic terminalsPostoperative periodRight hemisphere lesionsSpontaneous hyperactivityFrontal cortexIdentical injectionsHemisphere lesionsNanomolar dosesLeft hemisphereHyperactivityRatsNeural asymmetriesInjectionBehavioral responsesPrevious studiesLesionsCortexDosesWeeks