2010
Predictors of Multidrug- and Extensively Drug-Resistant Tuberculosis in a High HIV Prevalence Community
Andrews JR, Shah NS, Weissman D, Moll AP, Friedland G, Gandhi NR. Predictors of Multidrug- and Extensively Drug-Resistant Tuberculosis in a High HIV Prevalence Community. PLOS ONE 2010, 5: e15735. PMID: 21209951, PMCID: PMC3012092, DOI: 10.1371/journal.pone.0015735.Peer-Reviewed Original ResearchConceptsDrug-resistant tuberculosisTB treatment failureXDR-TBHIV prevalence settingsRisk factorsTreatment failureOdds ratioMDR/XDR-TBOnly significant risk factorRetrospective case-control studyDrug resistanceMDR-TB patientsSignificant risk factorsStrong risk factorMultivariate logistic regressionTB drug resistanceCase-control studyHigh HIV prevalence communitiesDemographic risk factorsDrug susceptibility testing methodsHIV prevalence communitiesTB settingsClinical deteriorationMDR-TBTB treatment
1998
Public Health Implications of Antiretroviral Therapy and HIV Drug Resistance
Wainberg M, Friedland G. Public Health Implications of Antiretroviral Therapy and HIV Drug Resistance. JAMA 1998, 279: 1977-1983. PMID: 9643862, DOI: 10.1001/jama.279.24.1977.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusDrug-resistant variantsDrug-resistant virusesHIV drug resistanceAntiviral therapyPublic health implicationsDrug resistanceGenital secretionsHealth implicationsPublic health importanceAntiretroviral therapyViral burdenAntiretroviral agentsPatient adherenceTreatment failureViral loadImmunodeficiency virusResistant virusesSustained reductionHealth importanceTherapyVirusChild routeBloodSecretion