2011
Spread of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa
Moodley P, Shah NS, Tayob N, Connolly C, Zetola N, Gandhi N, Friedland G, Sturm AW. Spread of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa. PLOS ONE 2011, 6: e17513. PMID: 21655324, PMCID: PMC3104985, DOI: 10.1371/journal.pone.0017513.Peer-Reviewed Original ResearchConceptsMDR-TB casesDrug-resistant tuberculosisXDR-TB casesXDR-TBDrug susceptibility test resultsExtensively Drug-Resistant TuberculosisMDR tuberculosis casesMDR-TB patientsXDR-TB patientsCulture-confirmed casesProvincial referral hospitalCross-sectional studyKwaZulu-Natal ProvinceSource of infectionTB casesNumber of hospitalsReferral hospitalSputum cultureTuberculosis casesScotland hospitalsPatientsHealthcare districtsHospitalClinical diagnosisLaboratory database
2009
HIV Coinfection in Multidrug- and Extensively Drug-Resistant Tuberculosis Results in High Early Mortality
Gandhi NR, Shah NS, Andrews JR, Vella V, Moll AP, Scott M, Weissman D, Marra C, Lalloo UG, Friedland GH. HIV Coinfection in Multidrug- and Extensively Drug-Resistant Tuberculosis Results in High Early Mortality. American Journal Of Respiratory And Critical Care Medicine 2009, 181: 80-86. PMID: 19833824, DOI: 10.1164/rccm.200907-0989oc.Peer-Reviewed Original ResearchConceptsXDR-TB casesHIV coinfection rateXDR-TB patientsOne-year mortalityTB casesXDR-TBTB patientsMDR-TBSputum collectionDrug-resistant tuberculosis epidemicHigh HIV prevalence regionsDrug susceptibility test resultsYear of diagnosisRetrospective observational studyHigh early mortalityAvailable medical recordsMajority of deathsHIV coinfectionAntiretroviral therapyHIV statusEarly mortalityMedical recordsTuberculosis resultsEarly initiationObservational study