2023
An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model
Charkoftaki G, Aalizadeh R, Santos-Neto A, Tan W, Davidson E, Nikolopoulou V, Wang Y, Thompson B, Furnary T, Chen Y, Wunder E, Coppi A, Schulz W, Iwasaki A, Pierce R, Cruz C, Desir G, Kaminski N, Farhadian S, Veselkov K, Datta R, Campbell M, Thomaidis N, Ko A, Thompson D, Vasiliou V. An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model. Human Genomics 2023, 17: 80. PMID: 37641126, PMCID: PMC10463861, DOI: 10.1186/s40246-023-00521-4.Peer-Reviewed Original ResearchConceptsCOVID-19 patientsDisease severityViral outbreaksFuture viral outbreaksLength of hospitalizationIntensive care unitWorse disease prognosisLife-threatening illnessEffective medical interventionsCOVID-19Clinical decision treeGlucuronic acid metabolitesNew potential biomarkersHospitalization lengthCare unitComorbidity dataSerotonin levelsDisease progressionHealthy controlsPatient outcomesDisease prognosisPatient transferPatientsHealthcare resourcesPotential biomarkers
2015
Serum Renalase Levels Correlate with Disease Activity in Lupus Nephritis
Qi C, Wang L, Zhang M, Shao X, Chang X, Fan Z, Cao Q, Mou S, Wang Q, Yan Y, Desir G, Ni Z. Serum Renalase Levels Correlate with Disease Activity in Lupus Nephritis. PLOS ONE 2015, 10: e0139627. PMID: 26431044, PMCID: PMC4592194, DOI: 10.1371/journal.pone.0139627.Peer-Reviewed Original ResearchConceptsSerum renalase levelsActive lupus nephritisLupus nephritisDisease activityProliferative lupus nephritisRenalase levelsLN patientsSystemic lupus erythematosusStandard therapyDisease progressionHealthy controlsActive LN patientsInactive lupus nephritisProliferative LN patientsSLEDAI-2KSLE disease activityUrine protein excretionKidneys of patientsCross-sectional studyExpression of renalaseCytokine-like proteinLupus erythematosusSerious complicationsProtein excretionSerum renalase