2022
Implementation opportunities for scaling up methadone maintenance treatment in Kyrgyzstan: Methadone dosage and retention on treatment over two years
Ivasiy R, Madden LM, Farnum SO, Shumskaya N, de Leon S, Bromberg DJ, Kurmanalieva A, Duishenaliev A, Tokubaev R, Altice FL. Implementation opportunities for scaling up methadone maintenance treatment in Kyrgyzstan: Methadone dosage and retention on treatment over two years. Drug And Alcohol Dependence Reports 2022, 4: 100075. PMID: 36267100, PMCID: PMC9581459, DOI: 10.1016/j.dadr.2022.100075.Peer-Reviewed Original ResearchMethadone maintenance treatmentDosage levelsMaintenance treatmentCox multivariate regression modelMethadone dosage levelsProspective observational databaseNational treatment guidelinesProportion of patientsHigher dosage levelsOptimal dosageMMT retentionMMT patientsMethadone dosageTreatment guidelinesHIV statusMultivariate regression modelHigh doseSurvival analysisTreatment dropoutClinical settingCost-effective strategySignificant predictorsMonthsHIVObservational database
2019
The accuracy of baseline viral load for predicting the efficacy of elbasvir/grazoprevir in participants with hepatitis C virus genotype 1a infection: An integrated analysis
Serfaty L, Jacobson I, Rockstroh J, Altice FL, Hwang P, Barr E, Robertson M, Haber B. The accuracy of baseline viral load for predicting the efficacy of elbasvir/grazoprevir in participants with hepatitis C virus genotype 1a infection: An integrated analysis. Journal Of Viral Hepatitis 2019, 26: 329-336. PMID: 30412325, DOI: 10.1111/jvh.13037.Peer-Reviewed Original ResearchMeSH KeywordsAmidesAntiviral AgentsBenzofuransCarbamatesCyclopropanesData Interpretation, StatisticalFemaleGenotypeHepacivirusHepatitis C, ChronicHumansImidazolesMalePredictive Value of TestsQuinoxalinesReproducibility of ResultsSensitivity and SpecificitySulfonamidesSustained Virologic ResponseViral LoadConceptsBaseline viral loadResistance-associated substitutionsNS5A resistance-associated substitutionsEBR/GZRElbasvir/grazoprevirGenotype 1a infectionViral loadNegative predictive valuePositive predictive valuePredictive valueBaseline NS5a resistance-associated substitutionsHepatitis C virus infectionPoor negative predictive valueEuropean treatment guidelinesC virus infectionSustained virologic responseHigh positive predictive valueEBR 50GT1a infectionVirologic failureVirologic responseTreatment guidelinesTreatment outcomesVirus infectionStratification factors
2017
Physician Decisions to Defer Antiretroviral Therapy in Key Populations: Implications for Reducing Human Immunodeficiency Virus Incidence and Mortality in Malaysia
Ferro EG, Culbert GJ, Wickersham JA, Marcus R, Steffen AD, Pauls HA, Westergaard RP, Lee CK, Kamarulzaman A, Altice FL. Physician Decisions to Defer Antiretroviral Therapy in Key Populations: Implications for Reducing Human Immunodeficiency Virus Incidence and Mortality in Malaysia. Open Forum Infectious Diseases 2017, 4: ofw219. PMID: 28480230, PMCID: PMC5414088, DOI: 10.1093/ofid/ofw219.Peer-Reviewed Original ResearchHuman immunodeficiency virusT-cell countsAdvanced human immunodeficiency virusAntiretroviral therapyKey risk populationsKey populationsRisk populationsEvidence-based treatment guidelinesHuman immunodeficiency virus (HIV) incidenceClinician-level interventionsHypothetical clinical scenariosProportion of physiciansHigher CD4HIV patientsPhysician adherenceControl patientsTreatment guidelinesHIV incidenceImmunodeficiency virusART accessART coverageInternet-based surveyPhysicians' attitudesPrevention strategiesClinical scenarios
2009
Hepatitis B Virus Infection in US Correctional Facilities: A Review of Diagnosis, Management, and Public Health Implications
Gupta S, Altice FL. Hepatitis B Virus Infection in US Correctional Facilities: A Review of Diagnosis, Management, and Public Health Implications. Journal Of Urban Health 2009, 86: 263-279. PMID: 19184447, PMCID: PMC2648882, DOI: 10.1007/s11524-008-9338-z.BooksConceptsChronic viral infectionsHepatitis B virus infectionB virus infectionReview of diagnosisHBV infectionViral infectionVirus infectionMedical careChronic HBV infectionChronic hepatitis BChronic medical conditionsComprehensive medical carePublic health burdenPublic health impactHigh-risk behaviorsPublic health implicationsProvision of vaccinationUS correctional facilitiesCorrectional settingsHBV vaccineHepatitis BViral hepatitisTreatment guidelinesChronic infectionChronic illness