2000
Prospective cohort study of children born to human immunodeficiency virus-infected mothers, 1985 through 1997: trends in the risk of vertical transmission, mortality and acquired immunodeficiency syndrome indicator diseases in the era before highly active antiretroviral therapy
SIMPSON J, SHAPIRO E, ANDIMAN W. Prospective cohort study of children born to human immunodeficiency virus-infected mothers, 1985 through 1997: trends in the risk of vertical transmission, mortality and acquired immunodeficiency syndrome indicator diseases in the era before highly active antiretroviral therapy. The Pediatric Infectious Disease Journal 2000, 19: 618-624. PMID: 10917219, DOI: 10.1097/00006454-200007000-00007.Peer-Reviewed Original ResearchConceptsAIDS indicator diseasesMonths of ageIndicator diseasesInfected childrenVertical transmissionCohort studyHuman immunodeficiency virus-infected mothersMycobacterium avium complex diseaseActive antiretroviral therapyHIV infection statusPerson monthsProspective cohort studyPneumocystis carinii pneumoniaLongitudinal cohort studyRate of deathIntroduction of treatmentTime of deathRates of diseaseAntiretroviral therapyHIV infectionCarinii pneumoniaPregnant womenAntiretroviral drugsHIV-1HIV
1997
Reduction in the Risk of Vertical Transmission of HIV-1 Associated with Treatment of Pregnant Women with Orally Administered Zidovudine Alone
Simpson B, Shapiro E, Andiman W. Reduction in the Risk of Vertical Transmission of HIV-1 Associated with Treatment of Pregnant Women with Orally Administered Zidovudine Alone. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1997, 14: 145-152. PMID: 9052723, DOI: 10.1097/00042560-199702010-00007.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdolescentAdultAnti-HIV AgentsCD4 Lymphocyte CountCohort StudiesDelivery, ObstetricFemaleHIV InfectionsHIV-1HumansInfantInfant, NewbornInfectious Disease Transmission, VerticalLongitudinal StudiesOdds RatioPregnancyPregnancy Complications, InfectiousProspective StudiesRetrospective StudiesRisk FactorsZidovudineConceptsRisk of transmissionT-lymphocyte countsMode of deliveryVertical transmissionHIV-1Cell countT-cell countsProspective cohort studyRisk of motherRoutine prenatal careSubgroup of womenChild transmissionUntreated womenCohort studyUntreated mothersPregnant womenPrenatal careObservational studyCD4ZidovudineSignificant associationWomenMothersRiskSignificant reduction