2023
Research Priorities in Critical Care Cardiology JACC Expert Panel
Miller P, Huber K, Bohula E, Krychtiuk K, Pöss J, Roswell R, Tavazzi G, Solomon M, Kristensen S, Morrow D, Care A. Research Priorities in Critical Care Cardiology JACC Expert Panel. Journal Of The American College Of Cardiology 2023, 82: 2329-2337. PMID: 38057075, PMCID: PMC10752230, DOI: 10.1016/j.jacc.2023.09.828.Peer-Reviewed Original ResearchMeSH KeywordsCardiologyCoronary Care UnitsCritical CareCritical IllnessHospital MortalityHumansIntensive Care UnitsResearchConceptsCardiac intensive care unitCritical care cardiologyHigh-quality evidencePatient populationIntensive care unitCritical care researchCare unitIll patientsSociety guidelinesClinical trialsPractice patternsCare researchExpert panelDiagnosisResearch prioritiesComorbiditiesPatientsPopulationLimited guidanceCliniciansCardiologyTrialsCare
2022
Patients With Acute Coronary Syndromes Admitted to Contemporary Cardiac Intensive Care Units: Insights From the CCCTN Registry
Fagundes A, Berg DD, Park JG, Baird-Zars VM, Newby LK, Barsness GW, Miller PE, van Diepen S, Katz JN, Phreaner N, Roswell RO, Menon V, Daniels LB, Morrow DA, Bohula EA, Investigators F. Patients With Acute Coronary Syndromes Admitted to Contemporary Cardiac Intensive Care Units: Insights From the CCCTN Registry. Circulation Cardiovascular Quality And Outcomes 2022, 15: e008652. PMID: 35862019, DOI: 10.1161/circoutcomes.121.008652.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeCoronary Care UnitsHospital MortalityHumansIntensive Care UnitsProspective StudiesRegistriesRetrospective StudiesConceptsCardiac intensive care unitAcute coronary syndromeContemporary cardiac intensive care unitsIntensive care unitCICU admissionAdmission indicationsCICU mortalityCoronary syndromeCare unitPrimary diagnosisIntensive care unit therapyEpidemiology of patientsNon-ACS diagnosisLow-risk patientsTime of admissionCICU lengthAcute severityVasoactive therapyPatient characteristicsRespiratory insufficiencyRisk patientsCommon indicationRoutine admissionACS admissionsProspective study
2021
The association between cardiac intensive care unit mechanical ventilation volumes and in-hospital mortality
Nandiwada S, Islam S, Jentzer JC, Miller PE, Fordyce CB, Lawler P, Alviar CL, Sun LY, Dover DC, Lopes RD, Kaul P, van Diepen S. The association between cardiac intensive care unit mechanical ventilation volumes and in-hospital mortality. European Heart Journal Acute Cardiovascular Care 2021, 10: 797-805. PMID: 34318875, PMCID: PMC9067446, DOI: 10.1093/ehjacc/zuab055.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitMechanical ventilationHospital mortalityRespiratory failureCICU LOSNon-invasive mechanical ventilationNational population-based dataInvasive mechanical ventilationVolume-mortality relationshipProlonged mechanical ventilationProportion of patientsHigh-volume hospitalsPercutaneous coronary interventionLow-volume centersHigh-volume centersIntensive care unitPopulation-based dataOutcomes of interestCICU lengthCICU admissionCoronary interventionSurgical ICUCare unitVolume centersLower incidenceTransition From an Open to Closed Staffing Model in the Cardiac Intensive Care Unit Improves Clinical Outcomes
Miller PE, Chouairi F, Thomas A, Kunitomo Y, Aslam F, Canavan ME, Murphy C, Daggula K, Metkus T, Vallabhajosyula S, Carnicelli A, Katz JN, Desai NR, Ahmad T, Velazquez EJ, Brennan J. Transition From an Open to Closed Staffing Model in the Cardiac Intensive Care Unit Improves Clinical Outcomes. Journal Of The American Heart Association 2021, 10: e018182. PMID: 33412899, PMCID: PMC7955420, DOI: 10.1161/jaha.120.018182.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitIntensive care unitHospital mortalityCare unitCICU mortalityClinical outcomesModern cardiac intensive care unitSurgical intensive care unitTotal hospital chargesSeverity of illnessMultivariable logistic regressionCICU lengthMultivariable adjustmentRespiratory insufficiencyPrimary outcomeUnique admissionsHospital chargesCardiac arrestSubgroup analysisImproved outcomesMortalityLogistic regressionAdmissionClosed unitStaffing models
2020
Prevalence of Noncardiac Multimorbidity in Patients Admitted to Two Cardiac Intensive Care Units and Their Association with Mortality
Miller PE, Thomas A, Breen TJ, Chouairi F, Kunitomo Y, Aslam F, Damluji AA, Anavekar NS, Murphy JG, van Diepen S, Barsness GW, Brennan J, Jentzer J. Prevalence of Noncardiac Multimorbidity in Patients Admitted to Two Cardiac Intensive Care Units and Their Association with Mortality. The American Journal Of Medicine 2020, 134: 653-661.e5. PMID: 33129785, PMCID: PMC8079541, DOI: 10.1016/j.amjmed.2020.09.035.Peer-Reviewed Original ResearchConceptsCritical care therapiesNoncardiac comorbiditiesCICU populationCare therapyLong-term adverse clinical outcomesCardiac intensive care unitIntensive care unit practiceBetter care pathwaysIncreased hospital mortalityNoncardiac organ failureUnique patient admissionsAdverse clinical outcomesIntensive care unitMultivariable logistic regressionLength of stayAcute cardiac illnessCICU patientsHospital mortalityNoncardiac indicationsICU admissionMultivariable adjustmentOrgan failureCare unitClinical outcomesCardiac illness
2019
Clinical Practice Patterns in Temporary Mechanical Circulatory Support for Shock in the Critical Care Cardiology Trials Network (CCCTN) Registry
Berg DD, Barnett CF, Kenigsberg BB, Papolos A, Alviar CL, Baird-Zars VM, Barsness GW, Bohula EA, Brennan J, Burke JA, Carnicelli AP, Chaudhry SP, Cremer PC, Daniels LB, DeFilippis AP, Gerber DA, Granger CB, Hollenberg S, Horowitz JM, Gladden JD, Katz JN, Keeley EC, Keller N, Kontos MC, Lawler PR, Menon V, Metkus TS, Miller PE, Nativi-Nicolau J, Newby LK, Park JG, Phreaner N, Roswell RO, Schulman SP, Sinha SS, Snell RJ, Solomon MA, Teuteberg JJ, Tymchak W, van Diepen S, Morrow DA. Clinical Practice Patterns in Temporary Mechanical Circulatory Support for Shock in the Critical Care Cardiology Trials Network (CCCTN) Registry. Circulation Heart Failure 2019, 12: e006635. PMID: 31707801, PMCID: PMC7008928, DOI: 10.1161/circheartfailure.119.006635.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiologistsCoronary Care UnitsExtracorporeal Membrane OxygenationFemaleHealthcare DisparitiesHeart-Assist DevicesHemodynamicsHumansIntra-Aortic Balloon PumpingMaleMiddle AgedNorth AmericaPatient AdmissionPractice Patterns, Physicians'Recovery of FunctionRisk FactorsSeverity of Illness IndexShock, CardiogenicTime FactorsTreatment OutcomeConceptsIntraaortic balloon pumpTemporary MCSCardiogenic shockIllness severityBalloon pumpPractice patternsAcute myocardial infarction-related cardiogenic shockCritical Care Cardiology Trials Network RegistryLower Sequential Organ Failure Assessment scoresSequential Organ Failure Assessment scoreTemporary mechanical circulatory support devicesVeno-arterial extracorporeal membrane oxygenationIntraaortic balloon pump useOrgan Failure Assessment scoreTemporary mechanical circulatory supportCardiac intensive care unitInfarction-related cardiogenic shockMechanical circulatory support devicesOverall practice patternsTemporary MCS devicesExtracorporeal membrane oxygenationSevere metabolic derangementHospital-level variationIntensive care unitMechanical circulatory support
2018
Positive Pressure Ventilation in the Cardiac Intensive Care Unit
Alviar CL, Miller PE, McAreavey D, Katz JN, Lee B, Moriyama B, Soble J, van Diepen S, Solomon MA, Morrow DA, Group A. Positive Pressure Ventilation in the Cardiac Intensive Care Unit. Journal Of The American College Of Cardiology 2018, 72: 1532-1553. PMID: 30236315, PMCID: PMC11032173, DOI: 10.1016/j.jacc.2018.06.074.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsContemporary cardiac intensive care unitsPositive pressure ventilationInvasive positive pressure ventilationCardiac intensive care unitIntensive care unitCare unitPressure ventilationNoninvasive positive pressure ventilationMechanical positive pressure ventilationCardiogenic pulmonary edemaProportion of patientsManagement of patientsRisk of complicationsMechanical circulatory supportComplex patient populationRight ventricular physiologyCICU mortalityCardiogenic shockRespiratory failurePulmonary edemaCirculatory supportCardiac arrestPatient populationVentricular physiologyMedical complexity