2024
Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the US
Kerekes D, Frey A, Prsic E, Tran T, Clune J, Sznol M, Kluger H, Forman H, Becher R, Olino K, Khan S. Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the US. JAMA Oncology 2024, 10: 342-351. PMID: 38175659, PMCID: PMC10767643, DOI: 10.1001/jamaoncol.2023.6025.Peer-Reviewed Original ResearchNon-small cell lung cancerEnd of lifeMonth of deathImmunotherapy initiationCohort studyMAIN OUTCOMEStage IV non-small cell lung cancerCharlson-Deyo comorbidity indexHigh metastatic burdenInitiation of immunotherapyNational prescribing patternsRisk-adjusted patientsImmune checkpoint inhibitorsRetrospective cohort studyStage IV melanomaPercentage of patientsHigh-volume centersLocation of metastasesLow-volume centersOdds of deathCell lung cancerNational Clinical DatabaseLow-volume facilitiesDrug Administration approvalCheckpoint inhibitors
2022
Association Between Postdischarge Medical Oncology Follow-Up Appointments and Downstream Health Care Use: A Single-Institution Experience
Xiang J, Chow R, Reynoso A, Carafeno T, Deshpande H, Strait M, Prsic E. Association Between Postdischarge Medical Oncology Follow-Up Appointments and Downstream Health Care Use: A Single-Institution Experience. JCO Oncology Practice 2022, 18: e1466-e1474. PMID: 35696632, DOI: 10.1200/op.21.00868.Peer-Reviewed Original ResearchConceptsHealth care useED visitsCare useOncology appointmentsAppointment timingPropensity score-matched analysisMultivariable logistic regression modelYale-New Haven HospitalRetrospective cohort studySingle institution experienceEmergency department visitsTertiary academic centerNew Haven HospitalLower ratesLogistic regression modelsOncology admissionsOncology followCause readmissionMost admissionsCohort studyDepartment visitsMedical oncologySubgroup analysisReadmissionAcademic centers
2015
Site of death, place of care, and burdensome transitions among patients with advanced solid tumor malignancies or leukemia between 2000 and 2010.
Prsic E, Teno J, Gozalo P. Site of death, place of care, and burdensome transitions among patients with advanced solid tumor malignancies or leukemia between 2000 and 2010. Journal Of Clinical Oncology 2015, 33: 144-144. DOI: 10.1200/jco.2015.33.29_suppl.144.Peer-Reviewed Original ResearchAcute hospital deathsDays of lifePlace of careHospital deathLeukemia patientsSite of deathBurdensome transitionsMultiple admissionsAdvanced solid tumor malignanciesIntensive care unit admissionMedicare beneficiaries 66 yearsEarly palliative careRate of ICUCare unit admissionRetrospective cohort studyMultiple hospital admissionsSolid tumor malignanciesMedicare billing dataUnit admissionMalignancy patientsAdvanced lungCohort studyUnit careHematology patientsHospital admission