2021
A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST)
Oikonomou EK, Van Dijk D, Parise H, Suchard MA, de Lemos J, Antoniades C, Velazquez EJ, Miller EJ, Khera R. A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST). European Heart Journal 2021, 42: 2536-2548. PMID: 33881513, PMCID: PMC8488385, DOI: 10.1093/eurheartj/ehab223.Peer-Reviewed Original ResearchMeSH KeywordsChest PainComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseHumansProspective StudiesConceptsStable chest painChest painPrimary endpointMajor adverse cardiovascular eventsNon-fatal myocardial infarctionAdverse cardiovascular eventsStudy's primary endpointCoronary artery diseaseClinical trial populationsCox regression modelParticipant-level dataSCOT-HEARTCardiovascular eventsCause mortalityHazard ratioPatients 5Artery diseaseFunctional testingPROMISE trialTrial populationMyocardial infarctionLower incidenceStudy populationPainCollected variables
2019
PET-Based Imaging of Ischemic Heart Disease
Chen K, Miller EJ, Sadeghi MM. PET-Based Imaging of Ischemic Heart Disease. PET Clinics 2019, 14: 211-221. PMID: 30826019, PMCID: PMC6426655, DOI: 10.1016/j.cpet.2018.12.003.Peer-Reviewed Original ResearchMeSH KeywordsComputed Tomography AngiographyCoronary Artery DiseaseCoronary CirculationCost-Benefit AnalysisFractional Flow Reserve, MyocardialHumansMultimodal ImagingMyocardial IschemiaMyocardial Perfusion ImagingPositron-Emission TomographyPrognosisRadiopharmaceuticalsSensitivity and SpecificityTomography, Emission-Computed, Single-PhotonConceptsIschemic heart diseaseHeart diseaseCoronary artery diseaseCardiac nuclear imagingCoronary flow reserveAtherosclerotic plaque vulnerabilityMyocardial blood flowCT myocardial perfusionArtery diseaseIschemic cardiomyopathyMicrovascular diseaseVascular calcificationFlow reserveVascular remodelingMyocardial viabilityPlaque vulnerabilityBlood flowMyocardial perfusionMolecular imaging toolDiseaseNuclear imagingImaging toolPETImagingPrognosis
2016
Visual identification of coronary calcifications on attenuation correction CT improves diagnostic accuracy of SPECT/CT myocardial perfusion imaging
Patchett ND, Pawar S, Miller EJ. Visual identification of coronary calcifications on attenuation correction CT improves diagnostic accuracy of SPECT/CT myocardial perfusion imaging. Journal Of Nuclear Cardiology 2016, 24: 711-720. PMID: 26850031, DOI: 10.1007/s12350-016-0395-5.Peer-Reviewed Original ResearchMeSH KeywordsArtifactsComputed Tomography AngiographyCoronary Artery DiseaseFemaleHumansImage EnhancementMaleMiddle AgedMyocardial Perfusion ImagingObserver VariationReproducibility of ResultsSensitivity and SpecificitySingle Photon Emission Computed Tomography Computed TomographyUser-Computer InterfaceVascular CalcificationConceptsCoronary artery calciumMyocardial perfusion imagingCT myocardial perfusion imagingSPECT/CT myocardial perfusion imagingInvasive coronary angiographyAttenuation correction CTCause mortalityLate revascularizationAbsence of CACAccuracy of MPIRetrospective chart reviewFalse-positive studiesCT myocardial perfusionArtery calciumChart reviewHazard ratioConsecutive patientsCoronary angiographyCoronary calcificationRisk stratificationRisk markersMore MIsCT scanMyocardial perfusionPatients