2022
Angiographic Pulse Wave Coherence in the Human Brain
Koch MJ, Duy PQ, Grannan BL, Patel AB, Raymond SB, Agarwalla PK, Kahle KT, Butler WE. Angiographic Pulse Wave Coherence in the Human Brain. Frontiers In Bioengineering And Biotechnology 2022, 10: 873530. PMID: 35592552, PMCID: PMC9110661, DOI: 10.3389/fbioe.2022.873530.Peer-Reviewed Original ResearchCerebral angiogramDiagnostic cerebral angiogramIntact human brainHuman brainRigid craniumPathophysiologic disturbancesArterial anatomyVenous bloodStroke volumeArterial bloodCardiac ratePhysiologic mechanismsHuman patientsNeurological pathologiesEquivalent volumePulse waveBrainAngiogramsCardiac cycleBloodFluoroscopic imagesVolume displacementFirst direct evidencePatientsArtery
2021
Inflammatory hydrocephalus
Robert SM, Reeves BC, Marlier A, Duy PQ, DeSpenza T, Kundishora A, Kiziltug E, Singh A, Allington G, Alper SL, Kahle KT. Inflammatory hydrocephalus. Child's Nervous System 2021, 37: 3341-3353. PMID: 34164718, DOI: 10.1007/s00381-021-05255-z.Peer-Reviewed Original ResearchConceptsPost-infectious hydrocephalusImmune cell profilesCerebrospinal fluid diversion techniquesPotential therapeutic vulnerabilitiesImportant protective responseCSF cytokinesProlong diseaseSustained inflammationHigher complicationsPreventable conditionClinical studiesNeurosurgical disordersReparative inflammationDistinct etiologiesHuman patientsHydrocephalusCell profilesProtective responseTherapeutic vulnerabilitiesPhysical irritantsCommon formInflammationDiversion techniquesDisordersFailure rate