2014
Resting state functional connectivity predicts neurofeedback response
Scheinost D, Stoica T, Wasylink S, Gruner P, Saksa J, Pittenger C, Hampson M. Resting state functional connectivity predicts neurofeedback response. Frontiers In Behavioral Neuroscience 2014, 8: 338. PMID: 25309375, PMCID: PMC4173810, DOI: 10.3389/fnbeh.2014.00338.Peer-Reviewed Original ResearchObsessive-compulsive disorderOrbitofrontal cortexFunctional connectivityNeurofeedback trainingState functional connectivityWhole-brain connectivityBrain functional connectivityResting-state fMRITarget brain regionsBrodmann area 10Clinical symptomatologyContamination anxietyProminent symptomAnterior prefrontal cortexBrain regionsNeuropsychiatric disordersRs-fMRIBehavioral improvementPrefrontal cortexSame protocolPilot dataBA 10Neurofeedback protocolReliable predictorCortex
2013
Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity
Scheinost D, Stoica T, Saksa J, Papademetris X, Constable RT, Pittenger C, Hampson M. Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity. Translational Psychiatry 2013, 3: e250-e250. PMID: 23632454, PMCID: PMC3641411, DOI: 10.1038/tp.2013.24.Peer-Reviewed Original ResearchConceptsResting-state connectivityContamination anxietyBrain regionsNF trainingBrain connectivityResting-state functional connectivityFunctional magnetic resonance imaging (fMRI) neurofeedbackPotential of neurofeedbackRelevant brain networksResting-state fMRIDorsolateral prefrontal cortexTarget brain regionsBrain functional architectureUseful therapyLimbic circuitryMatched subjectsOrbitofrontal regionsOrbitofrontal cortexFunctional connectivityPrefrontal cortexHuman emotionsFeedback control tasksSubclinical anxietyAnxiety regulationBrain networks
2012
Real-time fMRI biofeedback targeting the orbitofrontal cortex for contamination anxiety.
Hampson M, Stoica T, Saksa J, Scheinost D, Qiu M, Bhawnani J, Pittenger C, Papademetris X, Constable T. Real-time fMRI biofeedback targeting the orbitofrontal cortex for contamination anxiety. Journal Of Visualized Experiments 2012 PMID: 22297729, PMCID: PMC3462579, DOI: 10.3791/3535.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderOrbitofrontal cortexBrain areasContamination anxietySymptom severityQuarter of patientsSpecific brain areasClinical improvementControl subjectsClinical changesMagnetic resonance imaging dataHealthy subjectsPsychiatric disordersTherapeutic interventionsFunctional magnetic resonance imaging (fMRI) dataBrain regionsObsessive-compulsive symptomsBrain functionTraining subjectsOCD symptom severityBiofeedback interventionConsistent findingCortexBiofeedback trainingBiofeedback