Fundamental processes in the evolutionary ecology of Lyme borreliosis
Kurtenbach K, Hanincová K, Tsao J, Margos G, Fish D, Ogden N. Fundamental processes in the evolutionary ecology of Lyme borreliosis. Nature Reviews Microbiology 2006, 4: 660-669. PMID: 16894341, DOI: 10.1038/nrmicro1475.Peer-Reviewed Original ResearchConceptsEvolutionary ecologyGenetic changesMultiple-niche polymorphismVector-borne zoonosesB. burgdorferi s.Natural transmission cycleEvolutionary relationshipsEcological parallelsEvolutionary biologyVector-borne pathogensBurgdorferi s.Population fluctuationsProcess-based modelEcologySensu latoDifferent membersFundamental processesVector-borne diseasesPathogensTransmission cycleSpeciesBorrelia burgdorferi sensu latoSame fundamental questionsKey processesBurgdorferi sensu latoAn Ixodes scapularis protein required for survival of Anaplasma phagocytophilum in tick salivary glands
Sukumaran B, Narasimhan S, Anderson JF, DePonte K, Marcantonio N, Krishnan MN, Fish D, Telford SR, Kantor FS, Fikrig E. An Ixodes scapularis protein required for survival of Anaplasma phagocytophilum in tick salivary glands. Journal Of Experimental Medicine 2006, 203: 1507-1517. PMID: 16717118, PMCID: PMC2118316, DOI: 10.1084/jem.20060208.Peer-Reviewed Original ResearchConceptsA. phagocytophilum-infected miceRNA interference-mediated silencingA. phagocytophilumTick salivary proteinsI. scapularis salivary glandsRickettsia-like pathogensTick salivary glandsMammalian hostsGenus RickettsiaAnaplasma phagocytophilumGene expressionSalivary glandsIntracellular organismsArthropodsSalivary proteinsPathogensProteinPhagocytophilumExpressionTicksHuman anaplasmosisSilencingGenesOrganismsAnaplasma