2012
Predicted Outcomes of Vaccinating Wildlife to Reduce Human Risk of Lyme Disease
Tsao K, Fish D, Galvani AP. Predicted Outcomes of Vaccinating Wildlife to Reduce Human Risk of Lyme Disease. Vector-Borne And Zoonotic Diseases 2012, 12: 544-551. PMID: 22251312, DOI: 10.1089/vbz.2011.0731.Peer-Reviewed Original ResearchConceptsMice vaccinationTick biteB. burgdorferi transmissionLyme disease preventionTick blood mealVaccination outcomesHuman riskVaccination effortsDisease preventionLyme diseaseVaccinationInfection prevalenceBorrelia burgdorferiMiceWildlife vaccinationB. burgdorferiCausative agentPredicted outcomeBlood mealVector ticksBiteOutcomesBurgdorferiRiskWildlife reservoirs
2009
Effects of Tick Control by Acaricide Self-Treatment of White-Tailed Deer on Host-Seeking Tick Infection Prevalence and Entomologic Risk for Ixodes scapularis-Borne Pathogens
Hoen A, Rollend L, Papero M, Carroll J, Daniels T, Mather T, Schulze T, Stafford K, Fish D. Effects of Tick Control by Acaricide Self-Treatment of White-Tailed Deer on Host-Seeking Tick Infection Prevalence and Entomologic Risk for Ixodes scapularis-Borne Pathogens. Vector-Borne And Zoonotic Diseases 2009, 9: 431-438. PMID: 19650738, DOI: 10.1089/vbz.2008.0155.Peer-Reviewed Original ResearchConceptsEntomologic riskInfection prevalenceB. burgdorferiPrevalence of infectionFever group spirochetesBacterial coinfectionSelf treatmentTick infection prevalenceLyme diseaseBorrelia miyamotoiB. miyamotoiBacterial agentsPrevalenceBorrelia burgdorferiAnaplasma phagocytophilumA. phagocytophilumAdultsRiskBurgdorferiInfectionDiseaseHost-seeking ticksProportion of ticksAdult ticksTick control
2001
OspA Immunization Decreases Transmission of Borrelia burgdorferi Spirochetes from Infected Peromyscus leucopus Mice to Larval Ixodes scapularis Ticks
Tsao J, Barbour A, Luke C, Fikrig E, Fish D. OspA Immunization Decreases Transmission of Borrelia burgdorferi Spirochetes from Infected Peromyscus leucopus Mice to Larval Ixodes scapularis Ticks. Vector-Borne And Zoonotic Diseases 2001, 1: 65-74. PMID: 12653137, DOI: 10.1089/153036601750137705.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, WildAntibodies, BacterialAntigens, SurfaceArachnid VectorsBacterial Outer Membrane ProteinsBacterial VaccinesBorrelia burgdorferiDisease ReservoirsDose-Response Relationship, ImmunologicEnzyme-Linked Immunosorbent AssayFluorescent Antibody Technique, DirectHost-Parasite InteractionsIxodesLarvaLipoproteinsLyme DiseasePeromyscusConceptsControl miceUninfected larval ticksInfection prevalenceLarval Ixodes scapularis ticksB. burgdorferiNumber of spirochetesEnzyme-linked immunosorbentBorrelia burgdorferi spirochetesLevel of immunizationReservoir hostsConcentration of antibodyBorrelia burgdorferi transmissionIxodes scapularis ticksSecond vaccinationImmunized miceInfected miceLarval ticksPrior infectionVaccination programSubsequent riskDecrease transmissionOspA vaccinationDirect immunofluorescenceImmune responseXenodiagnostic ticks