2002
Heterogeneity, geographic distribution, and pathogenicity of serodemes of Leishmania viannia in Colombia.
Saravia NG, Weigle K, Navas C, Segura I, Valderrama L, Valencia AZ, Escorcia B, McMahon-Pratt D. Heterogeneity, geographic distribution, and pathogenicity of serodemes of Leishmania viannia in Colombia. American Journal Of Tropical Medicine And Hygiene 2002, 66: 738-44. PMID: 12224583, DOI: 10.4269/ajtmh.2002.66.738.Peer-Reviewed Original Research
1996
Leishmania amazonensis:Cultivation and Characterization of Axenic Amastigote-like Organisms
Hodgkinson V, Soong L, Duboise S, McMahon-Pratt D. Leishmania amazonensis:Cultivation and Characterization of Axenic Amastigote-like Organisms. Experimental Parasitology 1996, 83: 94-105. PMID: 8654556, DOI: 10.1006/expr.1996.0053.Peer-Reviewed Original ResearchConceptsAmastigote-like formsNorthern blot analysisDevelopmental biologyContinual cultureAxenic cultureMolecular biologyTransformation of promastigotesOrganismsDNA probesGeneration timeCultured amastigotesAxenic cultivationBlot analysisExpression levelsSpecies of LeishmaniaSpeciesProtein reactiveBiologyDegrees CFirst reportPeriod of growthAmastigotesPromastigotesLeishmania amazonensisCultivationLeishmania amazonensis:The Asian Rhesus Macaques (Macaca mulatta) as an Experimental Model for Study of Cutaneous Leishmaniasis
Amaral V, Ransatto V, Conceição-Silva F, Molinaro E, Ferreira V, Coutinho S, McMahon-Pratt D, Grimaldi G. Leishmania amazonensis:The Asian Rhesus Macaques (Macaca mulatta) as an Experimental Model for Study of Cutaneous Leishmaniasis. Experimental Parasitology 1996, 82: 34-44. PMID: 8617329, DOI: 10.1006/expr.1996.0005.Peer-Reviewed Original ResearchConceptsCutaneous leishmaniasisRhesus macaquesActive infectionPrimate modelT cellsPeripheral T-cell subpopulationsType hypersensitivity responseLevels of IgMT cell subpopulationsNonhuman primate modelCourse of infectionAsian rhesus macaquesLeishmanial antigensHomologous infectionMononuclear infiltrateProtective immunityHypersensitivity responseIgG antibodiesPathologic analysisLeishmanial infectionPlasma cellsSkin lesionsProliferative responseLesion sizeInitial infection
1992
Loss of the GP46/M-2 surface membrane glycoprotein gene family in the Leishmania braziliensis complex
McMahon-Pratt D, Traub-Cseko Y, Lohman K, Rogers D, Beverley S. Loss of the GP46/M-2 surface membrane glycoprotein gene family in the Leishmania braziliensis complex. Molecular And Biochemical Parasitology 1992, 50: 151-160. PMID: 1542309, DOI: 10.1016/0166-6851(92)90252-f.Peer-Reviewed Original ResearchConceptsGP46/MGene familyGlycoprotein gene familyMolecular karyotype analysisBraziliensis complexLeishmania braziliensis complexSpeciation eventsTrypanosomatid speciesPhylogenetic analysisCrithidia fasciculataLeishmania tarentolaeDevelopmental cycleWestern blot analysisLeishmania mexicana complexMembrane glycoproteinsKaryotype analysisBlot analysisL. braziliensis complexProtein expressionPolyclonal antiserumMexicana complexSpeciesL. panamensisLeishmania majorL. braziliensis
1990
Production of a specific monoclonal antibody for the identification of Leishmania (Leishmania) venezuelensis.
Hanham C, Shaw J, Lainson R, McMahon-Pratt D. Production of a specific monoclonal antibody for the identification of Leishmania (Leishmania) venezuelensis. American Journal Of Tropical Medicine And Hygiene 1990, 42: 453-9. PMID: 2187366, DOI: 10.4269/ajtmh.1990.42.453.Peer-Reviewed Original Research
1989
Flagellar Membrane and Paraxial Rod Proteins of Leishmania: Characterization Employing Monoclonal Antibodies
ISMACH R, CIANCI C, CAULFIELD J, LANGER P, HEIN A, McMAHON‐PRATT D. Flagellar Membrane and Paraxial Rod Proteins of Leishmania: Characterization Employing Monoclonal Antibodies. Journal Of Eukaryotic Microbiology 1989, 36: 617-624. PMID: 2689639, DOI: 10.1111/j.1550-7408.1989.tb01105.x.Peer-Reviewed Original ResearchConceptsDoublet of proteinsImmunocytochemical electron microscopic studyIndirect immunofluorescence experimentsRod proteinsMonoclonal antibody fFlagellar membraneSingle proteinDifferent proteinsFlagellar tipImmunofluorescence experimentsFlagellaParaxial rodProteinMonoclonal antibodiesAntibody FElectron microscopic experimentsMembraneLeishmaniaElectron microscopic studyMoleculesDAMicroscopic experimentsMicroscopic studyMonoclonal antibody techniqueLocalized patchesExtracellular Amastigote‐Like Forms of Leishmania panamensis and L. braziliensis. II. Stage‐ and Species‐Specific Monoclonal Antibodies
EPERON S, McMAHON‐PRATT D. Extracellular Amastigote‐Like Forms of Leishmania panamensis and L. braziliensis. II. Stage‐ and Species‐Specific Monoclonal Antibodies. Journal Of Eukaryotic Microbiology 1989, 36: 510-518. PMID: 2478699, DOI: 10.1111/j.1550-7408.1989.tb01087.x.Peer-Reviewed Original ResearchMonoclonal Antibodies Specific for Members of the Genus Endotrypanum
LOPES A, McMAHON‐PRATT D. Monoclonal Antibodies Specific for Members of the Genus Endotrypanum. Journal Of Eukaryotic Microbiology 1989, 36: 354-361. PMID: 2504911, DOI: 10.1111/j.1550-7408.1989.tb05526.x.Peer-Reviewed Original Research
1988
Membrane glycoprotein M-2 protects against Leishmania amazonensis infection
Champsi J, McMahon-Pratt D. Membrane glycoprotein M-2 protects against Leishmania amazonensis infection. Infection And Immunity 1988, 56: 3272-3279. PMID: 3182080, PMCID: PMC259734, DOI: 10.1128/iai.56.12.3272-3279.1988.Peer-Reviewed Original ResearchConceptsMouse strainsComplete protectionBALB/c strainLeishmania amazonensis infectionT cell immunityProtective immune responseOnset of infectionC. parvumAmazonensis infectionInfecting doseProtective immunityChallenge infectionC57BL/6 miceAntibody responseCBA miceComplete adjuvantEffective adjuvantImmune responseImmunized animalsLog phase promastigotesLevel of protectionL. amazonensisInfectionC strainLeishmania amazonensis