2009
Fanconi Anemia Complementation Group FANCD2 Protein Serine 331 Phosphorylation Is Important for Fanconi Anemia Pathway Function and BRCA2 Interaction
Zhi G, Wilson JB, Chen X, Krause DS, Xiao Y, Jones NJ, Kupfer GM. Fanconi Anemia Complementation Group FANCD2 Protein Serine 331 Phosphorylation Is Important for Fanconi Anemia Pathway Function and BRCA2 Interaction. Cancer Research 2009, 69: 8775-8783. PMID: 19861535, PMCID: PMC5912675, DOI: 10.1158/0008-5472.can-09-2312.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBRCA2 ProteinCell LineCheckpoint Kinase 1DNA DamageFanconi AnemiaFanconi Anemia Complementation Group D2 ProteinFanconi Anemia Complementation Group ProteinsHumansImmunoblottingImmunoprecipitationMass SpectrometryPhosphorylationProtein KinasesSequence Homology, Amino AcidSerineSignal TransductionConceptsS-phase checkpoint kinaseFanconi anemia DNA repair pathwayFanconi anemia pathwayRegulatory phosphorylation eventsDNA repair pathwaysFANCD1/BRCA2Phosphomimetic mutationBRCA2 interactionsPhosphorylation eventsSerine 331Checkpoint kinaseCancer susceptibility syndromeComplementation groupsRepair pathwaysPathway functionFanconi anemiaBone marrow failurePhosphorylationDownstream playersVivo interactionS331Susceptibility syndromeMarrow failurePathwayMonoubiquitylation
2007
Rbm15 Modulates Notch-Induced Transcriptional Activation and Affects Myeloid Differentiation
Ma X, Renda MJ, Wang L, Cheng EC, Niu C, Morris SW, S. AS, Krause DS. Rbm15 Modulates Notch-Induced Transcriptional Activation and Affects Myeloid Differentiation. Molecular And Cellular Biology 2007, 27: 3056-3064. PMID: 17283045, PMCID: PMC1899951, DOI: 10.1128/mcb.01339-06.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBasic Helix-Loop-Helix Transcription FactorsCell NucleusCHO CellsCricetinaeCricetulusDNA-Binding ProteinsDrosophila ProteinsGene Expression ProfilingHomeodomain ProteinsImmunoglobulin J Recombination Signal Sequence-Binding ProteinMiceMolecular Sequence DataMyeloid CellsMyelopoiesisNuclear ProteinsPromoter Regions, GeneticProtein BindingProtein Structure, TertiaryProtein TransportReceptors, NotchRNA, MessengerRNA, Small InterferingRNA-Binding ProteinsTranscription Factor HES-1Transcription, GeneticTranscriptional ActivationConceptsN-terminusPromoter activityMyeloid differentiationCell linesCell type-specific mannerMyeloid precursor cell linePrimary murine cellsType-specific mannerDominant negative effectStimulation of NotchHematopoietic cell linesHuman erythroleukemia cellsPrecursor cell lineMurine cell linesHematopoietic stem cellsTranscriptional activationHes1 transcriptionRNA interferenceErythroleukemia cellsFusion proteinHes1 promoter activityMurine cellsFusion partnerHematopoietic cellsRBM15
1996
CD34: Structure, Biology, and Clinical Utility
Krause D, Fackler M, Civin C, May W. CD34: Structure, Biology, and Clinical Utility. Blood 1996, 87: 1-13. PMID: 8547630, DOI: 10.1182/blood.v87.1.1.1.Peer-Reviewed Original ResearchAcute DiseaseAmino Acid SequenceAnimalsAntibodies, MonoclonalAntigens, CD34Antigens, NeoplasmBiomarkersCell AdhesionEndothelium, VascularFibroblastsGene Expression RegulationGenesHematopoietic Stem CellsHumansLeukemia, MyeloidMiceMolecular Sequence DataOrgan SpecificityProtein ConformationRNA Splicing