2019
Proinsulin Expressing Neuroendocrine Tumors of the Pancreas
Celli R, Tang LH, Cai G, Freedman-Weiss M, Colunga M, Salem RR, Majumdar S, Jain D. Proinsulin Expressing Neuroendocrine Tumors of the Pancreas. Pancreas 2019, 48: 55-59. PMID: 30451800, DOI: 10.1097/mpa.0000000000001196.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPancreatic neuroendocrine tumorsNeuroendocrine tumorsAvailable clinicopathologic dataIHC-negative tumorsSurgical oncology centersNormal insulin levelsIHC-positive tumorsSerum proinsulinClinicopathologic featuresPNET patientsClinicopathologic dataHypoglycemic patientsInsulin levelsProspective studyOncology centersSerum glucoseSuch tumorsClinical significanceInsulin immunohistochemistryRare casePatientsImmunohistochemistryProinsulinomaTumorsInsulinoma
2008
Adult nesidioblastosis. Clinicopathologic correlation between pre-operative selective arterial calcium stimulation studies and post-operative pathologic findings.
Kenney B, Tormey CA, Qin L, Sosa JA, Jain D, Neto A. Adult nesidioblastosis. Clinicopathologic correlation between pre-operative selective arterial calcium stimulation studies and post-operative pathologic findings. JOP Journal Of The Pancreas 2008, 9: 504-11. PMID: 18648143.Peer-Reviewed Original ResearchConceptsDifferential diagnosisDiffuse islet cell hyperplasiaPost-operative pathologic findingsMarked insulin releaseSevere hyperinsulinemic hypoglycemiaIslet cell hyperplasiaCase of nesidioblastosisIslet cell proliferationPancreatic ductal epitheliumRoutine diagnostic laboratoryFactitious hypoglycemiaRadiological findingsSevere hypoglycemiaSubtotal pancreatectomyPathologic findingsAdult nesidioblastosisCell hyperplasiaClinicopathologic correlationPancreatic segmentsDuctal epitheliumHyperinsulinemic hypoglycemiaCalcium challengeHistologic examinationLaboratory examinationsPartial pancreatectomy