2011
Enhancing alloreactivity does not restore GVHD induction but augments skin graft rejection by CD4+ effector memory T cells
Anderson BE, Tang AL, Wang Y, Froicu M, Rothstein D, McNiff JM, Jain D, Demetris AJ, Farber DL, Shlomchik WD, Shlomchik MJ. Enhancing alloreactivity does not restore GVHD induction but augments skin graft rejection by CD4+ effector memory T cells. European Journal Of Immunology 2011, 41: 2782-2792. PMID: 21660940, PMCID: PMC3517133, DOI: 10.1002/eji.201141678.Peer-Reviewed Original ResearchMeSH KeywordsAdoptive TransferAnimalsCD4-Positive T-LymphocytesDisease Models, AnimalGenes, T-Cell ReceptorGraft RejectionGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansImmunologic MemoryIsoantigensLymphocyte ActivationMicePostoperative ComplicationsSkin TransplantationT-Cell Antigen Receptor SpecificityT-Lymphocyte SubsetsConceptsEffector memory T cellsMemory T cellsSkin graft rejectionLymphopenia-induced proliferationT cellsMild GVHDAlloreactive clonesGraft rejectionAllogeneic hematopoietic stem cell transplantationHematopoietic stem cell transplantationT cell receptor repertoireGVHD effector cellsDonor T cellsStem cell transplantationDiverse T cell receptor repertoireNaive T cellsRapid skin graft rejectionAlloreactive repertoireGVHD inductionLimited GVHDHost diseaseLeukemia effectEffector cellsCell transplantationSyngeneic recipients
2009
Spectrum of histologic changes in colonic biopsies in patients treated with mycophenolate mofetil
Selbst MK, Ahrens WA, Robert ME, Friedman A, Proctor DD, Jain D. Spectrum of histologic changes in colonic biopsies in patients treated with mycophenolate mofetil. Modern Pathology 2009, 22: 737-743. PMID: 19329937, DOI: 10.1038/modpathol.2009.44.Peer-Reviewed Original ResearchMeSH KeywordsBiopsyColonGraft RejectionHumansImmunosuppressive AgentsMycophenolic AcidOrgan TransplantationConceptsSolid organ transplant patientsSelf-limited colitisMycophenolate mofetilInflammatory bowel diseaseOrgan transplant patientsColonic biopsiesHistologic changesHost diseaseGastrointestinal symptomsTransplant patientsBowel diseaseArchitectural distortionMycophenolate mofetil usePaneth cell metaplasiaSolid organ transplantationMofetil useInflammatory bowelMucin depletionCell metaplasiaImmunosuppressive agentsInflammatory infiltrateHistologic patternCase reportHistologic spectrumDiagnostic difficulties
2004
Total fibrous obliteration of main portal vein and portal foam cell venopathy in chronic hepatic allograft rejection.
Jain D, Robert ME, Navarro V, Friedman AL, Crawford JM. Total fibrous obliteration of main portal vein and portal foam cell venopathy in chronic hepatic allograft rejection. Archives Of Pathology & Laboratory Medicine 2004, 128: 64-7. PMID: 14692809, DOI: 10.5858/2004-128-64-tfoomp.Peer-Reviewed Original ResearchMeSH KeywordsAdultChildFemaleFoam CellsGraft RejectionHumansLiver TransplantationMaleMiddle AgedPortal VeinTransplantation, HomologousConceptsChronic hepatic allograft rejectionHepatic allograft rejectionBile duct lossFoam cell changeAllograft rejectionPortal veinChronic rejectionHepatic allograftsFibrous obliterationDuct lossExperienced liver pathologistMild luminal narrowingTwo-vessel diseaseCell changesHepatic artery occlusionHepatitis C cirrhosisCases of cirrhosisMain portal veinElastic van GiesonC cirrhosisGraft dysfunctionGraft lossPortal venopathyPortal hypertensionArtery occlusion