2022
Hepatic Adenomas in Patients 60 and Older Are Enriched for HNF1A Inactivation and Malignant Transformation
Yasir S, Chen ZE, Jain D, Kakar S, Wu TT, Yeh MM, Torbenson MS. Hepatic Adenomas in Patients 60 and Older Are Enriched for HNF1A Inactivation and Malignant Transformation. The American Journal Of Surgical Pathology 2022, 46: 786-792. PMID: 35383587, PMCID: PMC9469468, DOI: 10.1097/pas.0000000000001892.Peer-Reviewed Original ResearchConceptsPersons 60 yearsAtypical histologic featuresHepatic adenomaMalignant transformationControl groupOlder aged personInflammatory adenomasUnclassified adenomasHistologic featuresGroups of adenomasAged personsEarly malignant transformationYears of agePersons age 60Patients 60Persons 60Lipofuscin depositionMyxoid changeAge 60AdenomasBeta-catenin activationBeta-catenin pathwayAgeWomenMore years
2009
Molecular markers and death from prostate cancer.
Concato J, Jain D, Uchio E, Risch H, Li WW, Wells CK. Molecular markers and death from prostate cancer. Annals Of Internal Medicine 2009, 150: 595-603. PMID: 19414838, DOI: 10.7326/0003-4819-150-9-200905050-00005.Peer-Reviewed Original ResearchConceptsProstate-specific antigen levelProstate cancerLong-term riskAntigen levelsMicrovessel densityMedian prostate-specific antigen levelIncreased long-term riskVeterans Affairs Healthcare SystemIncident prostate cancerObservational cohort studyProportional hazards analysisTime of diagnosisHigher microvessel densityVeterans Health AdministrationBcl-2Years of ageProstate cancer biopsiesClinical care recordsClinical characteristicsCohort studyPatient ageMedian ageComorbid conditionsHistologic gradeResidual confounding