2021
Can primary hepatocellular carcinoma histomorphology predict extrahepatic metastasis?
Kumar D, Hafez O, Jain D, Zhang X. Can primary hepatocellular carcinoma histomorphology predict extrahepatic metastasis? Human Pathology 2021, 113: 39-46. PMID: 33905775, DOI: 10.1016/j.humpath.2021.04.008.Peer-Reviewed Original ResearchConceptsMetastatic hepatocellular carcinomaHepatocellular carcinomaHistologic patternHistomorphologic featuresPrimary tumorMetastatic tumorsMacrotrabecular-massive hepatocellular carcinomaCommon histologic patternPathogenesis of metastasisSignificant intratumoral heterogeneityExtrahepatic metastasesLymph nodesMicrovascular invasionAdrenal glandCommon subtypeNoncirrhotic liverCirrhotic liverCommon siteMetastatic tissuesLarge cohortAbdominal cavityHCC subtypesPathology archivesMetastasisHCC metastasis
2005
Composite Glandular and Endocrine Tumors of the Stomach With Pancreatic Acinar Differentiation
Jain D, Eslami-Varzaneh F, Takano AM, Ayer U, Umashankar R, Muller R, Klimstra DS. Composite Glandular and Endocrine Tumors of the Stomach With Pancreatic Acinar Differentiation. The American Journal Of Surgical Pathology 2005, 29: 1524-1529. PMID: 16224221, DOI: 10.1097/01.pas.0000169498.89035.f9.Peer-Reviewed Original ResearchConceptsPancreatic acinar differentiationGlandular componentAbdominal painCytokeratin 20Endocrine tumorsCytokeratin 7Acinar differentiationEndocrine componentElevated serum lipase levelsPerigastric lymph nodesSerum lipase levelsExocrine pancreatic enzymesIntestinal goblet cellsColumnar epithelial cellsGastrointestinal hemorrhageLymph nodesAcute pancreatitisClinicopathologic findingsGastric foveolarLipase levelsPrimary tumorGastric neoplasmsComposite tumorImmunohistochemical stainsPancreatic polypeptide