2000
Immunocytochemical Characterization of Murine Hex, a Homeobox-Containing Protein
Ghosh B, Ganea G, Denson L, Iannucci R, Jacobs H, Bogue C. Immunocytochemical Characterization of Murine Hex, a Homeobox-Containing Protein. Pediatric Research 2000, 48: 634-638. PMID: 11044484, DOI: 10.1203/00006450-200011000-00014.Peer-Reviewed Original ResearchConceptsMouse embryosGlutathione S-transferase fusion proteinS-transferase fusion proteinDivergent homeobox genesWhole mouse embryosTerminal amino acidsHepatic specificationHex proteinHomeobox genesMouse developmentDefinitive endodermBlood islandsNuclear localizationEndodermal cellsFusion proteinHex expressionProtein presentCultured cellsAmino acidsWhole mountsConfocal microscopyHepatic diverticulumProteinEmbryosWestern blotHex expression suggests a role in the development and function of organs derived from foregut endoderm
Bogue C, Ganea G, Sturm E, Ianucci R, Jacobs H. Hex expression suggests a role in the development and function of organs derived from foregut endoderm. Developmental Dynamics 2000, 219: 84-89. PMID: 10974674, DOI: 10.1002/1097-0177(2000)9999:9999<::aid-dvdy1028>3.0.co;2-5.Peer-Reviewed Original ResearchConceptsExtrahepatic biliary ductsMature animalsMaintenance of functionThymus originatesAdult thyroidDorsal pancreatic budLung expressionBile ductBiliary ductsThymic expressionFunction of organsDuct epitheliumLungThyroidE16.5 embryosLiverEpithelial cellsThymusSeptum transversumMesenchymal cellsPotential roleHex expressionDetectable levelsPharyngeal pouchesOrgansHNF3β and GATA-4 transactivate the liver-enriched homeobox gene, Hex
Denson L, McClure M, Bogue C, Karpen S, Jacobs H. HNF3β and GATA-4 transactivate the liver-enriched homeobox gene, Hex. Gene 2000, 246: 311-320. PMID: 10767553, DOI: 10.1016/s0378-1119(00)00082-2.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell LineCOS CellsDNADNA-Binding ProteinsGATA4 Transcription FactorGenes, HomeoboxHepatocyte Nuclear Factor 3-betaHomeodomain ProteinsHumansLiverLuciferasesMaleMiceMolecular Sequence DataNuclear ProteinsPlasmidsPromoter Regions, GeneticProtein BindingRatsRats, Sprague-DawleyRecombinant Fusion ProteinsSequence Analysis, DNASp1 Transcription FactorSp3 Transcription FactorTranscription FactorsTranscriptional ActivationTransfectionTumor Cells, Cultured
1999
Genomic structure, cDNA mapping, and chromosomal localization of the mouse homeobox gene, Hex
Ghosh B, Jacobs H, Wiedemann L, Brown A, Bedford F, Nimmakayalu M, Ward D, Bogue C. Genomic structure, cDNA mapping, and chromosomal localization of the mouse homeobox gene, Hex. Mammalian Genome 1999, 10: 1023-1025. PMID: 10501975, DOI: 10.1007/s003359901152.Peer-Reviewed Original ResearchAmino Acid SequenceAnimalsBase SequenceChromosome MappingCloning, MolecularCrosses, GeneticGenes, HomeoboxGenetic LinkageGenetic MarkersHomeodomain ProteinsIn Situ Hybridization, FluorescenceLiverMiceMice, Inbred StrainsMolecular Sequence DataRestriction MappingSequence AnalysisTranscription Factors