2020
Prior history of acute pancreatitis predicts poor survival in patients with resectable pancreatic ductal adenocarcinoma
Gong Y, Fan Z, Luo G, Huang Q, Qian Y, Cheng H, Jin K, Ni Q, Yu X, Liu C. Prior history of acute pancreatitis predicts poor survival in patients with resectable pancreatic ductal adenocarcinoma. Pancreatology 2020, 20: 716-721. PMID: 32249060, DOI: 10.1016/j.pan.2020.02.016.Peer-Reviewed Original ResearchConceptsHistory of APPancreatic ductal adenocarcinomaResectable pancreatic ductal adenocarcinomaPancreatic ductal adenocarcinoma patientsLog-rank testAcute pancreatitisSurgical resectionDuctal adenocarcinomaPoor survivalHazard ratioHistory of acute pancreatitisDiagnosis of pancreatic ductal adenocarcinomaAssociated with poor survivalIndependent survival predictorMultivariable-adjusted hazard ratiosKaplan-Meier methodRetrospective cohort studyCox proportional hazards modelsProportional hazards modelOverall survivalRemote historyClinical characteristicsCohort studyMultivariate analysisRisk factors
2016
Which patients with para-aortic lymph node (LN16) metastasis will truly benefit from curative pancreaticoduodenectomy for pancreatic head cancer?
Liu C, Lu Y, Luo G, Cheng H, Guo M, Liu Z, Xu J, Long J, Liu L, Fu D, Ni Q, Li M, Yu X. Which patients with para-aortic lymph node (LN16) metastasis will truly benefit from curative pancreaticoduodenectomy for pancreatic head cancer? Oncotarget 2016, 7: 29177-29186. PMID: 27081079, PMCID: PMC5045387, DOI: 10.18632/oncotarget.8690.Peer-Reviewed Original ResearchConceptsPancreatic head cancerResectable pancreatic head cancerLymph node ratioHead cancerLymph nodesTumor locationPara-aortic lymph node dissectionPara-aortic lymph node metastasisPara-aortic lymph nodesCurative surgical resectionLymph node dissectionIndependent prognostic factorLymph node metastasisPoor surgical outcomesDuctal adenocarcinoma patientsPoor prognostic markerPreoperative serum CA125Curative pancreaticoduodenectomyNode dissectionPancreatic headRadical surgerySurgical resectionNode metastasisPrognostic factorsSuch patients
2010
Clonal Expansion of Normal-Appearing Human Hepatocytes during Chronic Hepatitis B Virus Infection
Mason W, Liu C, Aldrich C, Litwin S, Yeh M. Clonal Expansion of Normal-Appearing Human Hepatocytes during Chronic Hepatitis B Virus Infection. Journal Of Virology 2010, 84: 8308-8315. PMID: 20519397, PMCID: PMC2916518, DOI: 10.1128/jvi.00833-10.Peer-Reviewed Original ResearchConceptsChronic hepatitis B virus infectionHepatitis B virus infectionB virus infectionExtensive clonal expansionClonal expansionHBV DNAInfected hepatocytesNoncirrhotic liverVirus infectionHepatocellular carcinomaImmune killingHuman HBV carriersNormal-appearing hepatocytesHuman hepatocytesWoodchuck hepatitis virusIntegrated HBV DNAHBV carriersSurgical resectionChronic infectionHepatitis virusNoncancerous liverInfectionLiverTissue sectionsHepatocytes
2008
Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells
Shangguan D, Meng L, Cao Z, Xiao Z, Fang X, Li Y, Cardona D, Witek R, Liu C, Tan W. Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells. Analytical Chemistry 2008, 80: 721-728. PMID: 18177018, DOI: 10.1021/ac701962v.Peer-Reviewed Original ResearchConceptsLiver cancerLiver cancer cellsEarly diagnosisCell linesBALB/cJ miceCancer cellsSurgical resectionClinical outcomesLiver cell lineEffective treatmentMouse modelWhole live cellsDeadly cancerCurrent studyCancer-specific aptamersTumor selectionBasic mechanism studiesCancerMost cancersBNL CLCancer early diagnosisCell-SELEX methodNoncancer cell linesDiagnosisCancer recognition
2006
Combined hepatic resection and radiofrequency ablation for multiple hepatic adenomas
Fujita S, Kushihata F, Herrmann G, Mergo P, Liu C, Nelson D, Fujikawa T, Hemming A. Combined hepatic resection and radiofrequency ablation for multiple hepatic adenomas. Journal Of Gastroenterology And Hepatology 2006, 21: 1351-1354. PMID: 16872326, DOI: 10.1111/j.1440-1746.2006.03184.x.Peer-Reviewed Original Research